Chemical Name | Cis-4-Hydroxy-L-Proline |
CAS Number | 618-27-9 |
Synonym |
cis-4-Hydroxy-L-proline
{LY} cis-4-Hydroxy-L-proline
{} {LY} cis-4-Hydroxy-L-proline
{} {} {LY} cis-4-Hydroxy-L-proline
{} {} {} {LY} cis-4-Hydroxy-L-proline
{} {} {} {} {LY} cis-4-Hydroxy-L-proline
{} {} {} {} {} {LY} cis-4-Hydroxy-L-proline
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{} {} {} {} {} {} {} {} {} {LY} cis-4-Hydroxy-L-proline
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EC Number | 210-542-1 |
Beilstein Registry Number | 81440 |
MDL Number | MFCD00064319 |
PubChem Substance ID | 440015 |
Chemical Name Translation | 顺式-4-羟基-L-脯氨酸 |
Reaxys-RN | 81440 |
Merck Number | 4840 |
LabNetwork Molecule ID | LN00335236 |
InChI | InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4-/m0/s1 |
Canonical SMILES | O=C(O)[C@H](C1)NC[C@H]1O |
Signal word |
Danger |
GHS Symbol
WGK Germany | 3 |
Safety Statements | |
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
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Risk Statements | |
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
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Precautionary statements | |
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P312
- P302+P352
- P304+P312
- P304+P340
- P305+P351+P338
- P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
- P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
- P322 Specific measures (see …on this label). 具体治疗(见本标签上的)。
- P330 Rinse mouth. 漱口
- P332+P313
- P337+P313
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
- P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
- P403+P233
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
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Personal Protective Equipment |
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
Storage condition |
2-8°C
{LY} 2-8°C
Store at RT.
{} {LY} 2-8°C
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{} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C |
Hazard statements | |
- H302 Harmful if swallowed 吞食有害
- H312 Harmful in contact with skin 皮肤接触有害
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H332 Harmful if inhaled 吸入有害
- H335 May cause respiratory irritation 可能导致呼吸道刺激
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Amanita sp.多肽毒素的组成部分,但不像胶原蛋白那样,它不属于动物蛋白
{MCE} [2]. Kao WW, et, al. Proline analogue removes fibroblasts from cultured mixed cell populations. Nature. 1977 Mar 3;266(5597):63-4.
{MCE} [3]. Tan EM, et, al. Proline analogues inhibit human skin fibroblast growth and collagen production in culture. J Invest Dermatol. 1983 Apr;80(4):261-7.
{MCE} [4]. Riley DJ, et, al. Prevention of bleomycin-induced pulmonary fibrosis in the hamster by cis-4-hydroxy-l-proline. Am Rev Respir Dis. 1981 Apr;123(4 Pt 1):388-93.
{TRC} Lawrence, C., et al.: Biochem. J., 313, 185 (1996),
{ALD} Merck: 14,4840
{ALD} Merck: 14,4840
Beilstein:22(5)5,7
{MCE} [1]. Lewko WM, et, al. Sensitivity of N-nitrosomethylurea-induced rat mammary tumors to cis-hydroxyproline, an inhibitor of collagen production. Cancer Res. 1981 Jul;41(7):2855-62.
{MCE} [1]. Lewko WM, et, al. Sensitivity of N-nitrosomethylurea-induced rat mammary tumors to cis-hydroxyproline, an inhibitor of collagen production. Cancer Res. 1981 Jul;41(7):2855-62.
{MCE} [2]. Kao WW, e