Trimethyl phosphite 三甲氧基磷

规格:
CAS: 121-45-9
产品编号: Bellen10003692
MDL: MFCD00008350
品牌: Bellen
Chemical NameTrimethyl phosphite
Synonym phosphorous acid trimethyl ester P(OMe)3 PHOSPHOROUS ACID TRIMETHYL ESTER 亚磷酸三甲酯 溶液 Trimethylfosfit Phosphorigsuretrimethylester Trimethylphosphite,97% 三甲基亞磷 三甲羥基亞磷酸 Trimethyl phosphite TRIMETHYL PHOSPHITE Trimethoxyphosphine Phosphonousacidtrimethylester Phosphorous acid trimethyl ester Fosforyn trojmetylowy TrimethyPhosphite Phosphorous acid, trimethyl ester Phosphorigsäuretrimethylester AURORA KA-1230 亚磷酸三甲酯 fosforyntrojmetylowy Trimethoxyfosfin P(OCH3)3 TRIMETHYL PHOSPHITE, 99+%, NMR GRADE TRIMETHYL PHOSPHITE, 99+% TRIMETHYL PHOSPHONATE Trimethyl phosphit
PubChem Substance ID8472
EC Number204-471-5
Beilstein Registry Number956570
Chemical Name Translation三甲氧基磷
Wiswesser Line Notation1OPO1&O1
InChIInChI=1S/C3H9O3P/c1-4-7(5-2)6-3/h1-3H3
MDL NumberMFCD00008350
CAS Number121-45-9
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ALBRW* Albright & Wilson Inc.  (P.O. Box 26229, Richmond, VA 23260-6229)
   Volume(issue)/page/year: #OPB-3,1984

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >10000 ppm/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   34,286,1973

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIHAAP American Industrial Hygiene Association Journal.  (AIHA, 475 Wolf
   Ledges Pkwy., Akron, OH 44311)  V.19-    1958-  Volume(issue)/page/year:
   34,286,1973

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4180 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ENVRAL Environmental Research.  (Academic Press, Inc., 1 E. First St.,
   Duluth, MN 55802) V.1-    1967-  Volume(issue)/page/year: 9,1,1975

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1640 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - urogenital system
   Reproductive - Specific Developmental Abnormalities - homeostasis
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   72,119,1984

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1640 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - Central Nervous System
   Reproductive - Specific Developmental Abnormalities - craniofacial
   (including nose and tongue)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   72,119,1984

WGK Germany3
Hazard Codes F,T F,Xi Xn
Hazard statements
  • H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H315 Causes skin irritation 会刺激皮肤
  • H304 May be fatal if swallowed and enters airways 吞食和进入呼吸道可能致命
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H350 May cause cancer 可能致癌
  • H340 May cause genetic defects 可能导致遗传性缺陷
  • H318 Causes serious eye damage 严重伤害眼睛
  • H372 Causes damage to organs through prolonged or repeated exposure 长期或频繁接触会损伤器官
  • H302 Harmful if swallowed 吞食有害
  • H226 Flammable liquid and vapour 易燃液体和蒸气
    Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
    RTECSTH1400000
    Precautionary statements
    • P308+P313
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
    • P370+P378
    • P201 Obtain special instructions before use. 使用前获取专门指示。
    • P403+P235
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P305+P351+P338
      Signal word Danger
      UN Number 2329 UN 2329 3/PG 3 UN2329
      Risk Statements
      • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      • R22 Harmful if swallowed 吞咽有害
      • R10 Flammable 易燃
      • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
      • R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
      • R11 Highly flammable 非常易燃
      • R48/23/24/25
      • R46 May cause inheritable genetic damage 可能引起遗传基因损害
      • R45 May cause cancer 可能致癌
      • R65 Harmful: may cause lung damage if swallowed 若吞咽可能伤害肺部器官
      • R36 Irritating to eyes 刺激眼睛
      • R66 Repeated exposure may cause skin dryness or cracking 反复接触可能导致皮肤干燥或皴裂
      • R67 Vapours may cause drowsiness and dizziness 蒸汽可能导致嗜睡和昏厥
      • R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
        Safety Statements
        • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
        • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
        • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
        • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
        • S39 Wear eye/face protection 戴眼睛/面孔保护装置;
        • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
        • S62 If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label where possible 吞食后不要催吐:立即求医并出示该容器或标签;
        • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
        • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
          Storage condition Air & Moisture Sensitive 2-8°C
          Packing GroupIII
          Hazard Class3
          Warnings 危化品目录(2015)
          Restrict 危险品
        • {SA} Aldrich MSDS 1 , 1795:C / Corp MSDS 1 (2), 3494:A / FT-IR 1 (1), 910:A / FT-IR 2 (1), 1544:D / FT-NMR 1 (1), 1465:C / IR-Spectra (2), 486:A / IR-Spectra (3), 548:B / NMR-Reference 2 (2), 862:B / RegBook 1 (1), 1093:A / Sax 6 , 2674 / Sigma FT-IR 1 (2), 958:B / Structure Index 1 , 168:C:9 / Vapor Phase 3 , 838:B
        • {SA} Beil. 1 ,IV,1256
        • {SA} Fieser 1 ,1233 / Fieser 2 ,439 / Fieser 3 ,315 / Fieser 4 ,541 / Fieser 5 ,717 / Fieser 7 ,393 / Fieser 9 ,490 / Fieser 11 ,570 / Fieser 12 ,536
        • {uni_hamburg} Short: II/2
        • Title: Magnetic Properties of Coordination and Organometallic Transition Metal Compounds
        • Author: König, E.
        • Editor: Hellwege, K.-H.; Hellwege, A.M.
        • Source: Landolt-Börnstein, New Series
        • Volume: II/2
        • Year: 1966
        • ISBN: 3-540-03593-1
        • ISBN: 978-3-540-03593-0
        • Internet Resource: DOI:10.1007/b19948
        • RefComment: 170 figs., XII, 578 pages. Hardcover
        • Abstract: The data compiled refer to susceptibility measurements (susceptibility, Curie-constants, magnetic moments, transition temperatures) and ESR-measurements (g-factors and other parameters of the applied spin Hamiltonian). In volume II/2 the literature from 1899 up to 1964 has been considered. Volume II/8 supplements volume II/2, taking into account the data on magnetic susceptibilities and ESR parameters published in the p eriod 1964 to 1968. The following subvolumes II/10,II/11, II/12 supplement data up to 1974.
        • {uni_hamburg} Short: II/25C
        • Title: Structure Data Of Free Polyatomic Molecules: Molecules containing Three or Four Carbon Atoms
        • Author: Graner, G.; Hirota, E.; Iijima, T.; Kuchitsu, K.; Ramsay, D.A.; Vogt, J.; Vogt, N.
        • Editor: Kuchitsu, K.
        • Source: Landolt-Börnstein, New Series
        • Volume: II/25C
        • Year: 2001
        • Keyword: Free Polyatomic Molecules; Carbon Atoms; Molecules
        • ISBN: 3-540-66774-1
        • ISBN: 978-3-540-66774-2
        • Internet Resource: DOI:10.1007/b71431
        • RefComment: VIII, 481 pages. Hardcover
        • Abstract: This volume c
        • 121-45-9 Bellen10003692 Trimethyl phosphite
三甲氧基磷

          化学属性

          Refractive indexn20/D 1.408(lit.)
          Melting Point-78 °C (lit.)
          TSCAYes
          Vapor Density4.3 (vs air)
          Vapor Pressure17 mmHg ( 20 °C)
          Solubility不溶于水,溶于多数有机溶剂。
          Mol. FormulaC3H9O3P
          Mol. Weight124.08
          Density1.052
          Flash Point82°F
          Appearance colorless liq.
          Stabilityair sensitive
          Boiling Point110-112°C

          *以上化合物性质及应用等信息仅供参考