n-Butyllithium 正丁基锂

规格: 1.6 M solution in Hexanes, SpcSeal
CAS: 109-72-8
产品编号: H12002
MDL: MFCD00009414
品牌: INFI
Chemical Namen-Butyllithium
CAS Number109-72-8
EC Number203-698-7
Beilstein Registry Number1209227
MDL NumberMFCD00009414
Synonym BUTYLLITHIUM SOLUTION, ~2.7 M IN HEPTANE 丁基锂 正丁基锂1.6M正己烷溶液 n-Butyllithium solution N-BULI 正丁基锂, 1.6M IN HEXANE BUTYLLITHIUM, 10.0M SOLUTION IN HEXANES 正丁基锂,1.6M在正己烷溶液 正丁基锂 butyl-lithiu 正丁基锂,2.5M正己烷溶液 BUTYLLITHIUM SOLUTION, ~1.6 M IN HEXANE n-utyllithium LITHIUM-1-BUTANIDE BUTYLLITHIUM, 1.6M SOLUTION IN HEXANES BUTYLLITHIUM, 2.0M SOLUTION IN PENTANE 正丁基锂, 2.2M IN HEXANE 正丁基锂2.6M甲苯溶液 Lithium-1-butanide Lithiumn-butyl 正丁基锂, 2.5M IN HEXANE (NOT IN SEPTUM CAP BOTTLE) Butyllithium solution BUTYLLITHIUM SOLUTION, ~2.5 M IN TOLUENE ButyllithiuminhexaneM 正丁基鋰 正丁基锂,2.2M溶于环己烷
PubChem Substance ID61028
Reaxys-RN1209227
Chemical Name Translation正丁基锂
LabNetwork Molecule IDLN00223799
InChIInChI=1S/C4H9.Li/c1-3-4-2;/h1,3-4H2,2H3;/q-1;+1
GHS Symbol
Signal word
WGK Germany2
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S20 When using do not eat or drink 使用时，不得进食，饮水；
  • S7/8 Keep container tightly closed and dry 保存在严格密闭容器中，保持干燥；
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾；
  • S33 Take precautionary measures against static discharges 对静电采取预防措施；
  • S57 Use appropriate containment to avoid environmental contamination 使用适当容器避免环境污染；
  • S30 Never add water to this product 切勿将水加入该产品中；
  • S43 In case of fire use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add -?Never use water) 着火时使用（指明具体的消防器材种类，如果用水增加危险，注明“禁止用水”
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
  • S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S9 Keep container in a well-ventilated place 保持容器在通风良好的场所；
  • S6 Keep under ... (inert gas to be specified by the manufacturer) 将该物质保存在生产厂家指定的惰性气体中；
  • S46 If swallowed, seek medical advice immediately and show this container or label 食入时，立即求医并出示容器/标签；
  • S62 If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label where possible 吞食后不要催吐：立即求医并出示该容器或标签；
    Risk Statements
    • R17 Spontaneously flammable in air 在空气中能够自燃
    • R11 Highly flammable 非常易燃
    • R14/15 Reacts violently with water, liberating extremely flammable gases 遇水剧烈反应，释放出高度可燃气体
    • R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
    • R48/20
    • R67 Vapours may cause drowsiness and dizziness 蒸汽可能导致嗜睡和昏厥
    • R65 Harmful: may cause lung damage if swallowed 若吞咽可能伤害肺部器官
    • R35 Causes severe burns 会导致严重灼伤
    • R34 Causes burns 会导致灼伤
    • R62 Possible risk of impaired fertility 有削弱生殖能力的危险
    • R51/53
    • R50/53
    • R15 Contact with water liberates extremely flammable gases 遇水会释放出极端易燃的气体
    • R66 Repeated exposure may cause skin dryness or cracking 反复接触可能导致皮肤干燥或皴裂
    • R12 Extremely flammable 极端易燃
    • R14 Reacts violently with water 遇水会猛烈反应
    • R52/53
      Precautionary statements
      • P222 Do not allow contact with air. 不要与空气接触。
      • P335+P334
      • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
      • P223 Keep away from any possible contact with water, because of violent reaction and possible flash fire. 远离任何与水接触的可能，因为会剧烈反应可能产生闪火。
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P301+P330+P331+P310
      • P370+P378
      • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
      • P273 Avoid release to the environment. 避免释放到环境中。
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P422 Store contents under… 存储目录在…之下。
      • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
      • P231 Handle under inert gas. 在惰性气体中操作。
      • P308+P313
      • P403+P233
      • P305+P351+P338+P310
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
        Hazard statements
        • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
        • H304 May be fatal if swallowed and enters airways 吞食和进入呼吸道可能致命
        • H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
        • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
        • H261 In contact with water releases flammable gas 与水接触时释放可燃气体。
        • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
        • H250 Catches fire spontaneously if exposed to air 暴露于空气自发着火
        • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
        • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
        • H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
        • H260 In contact with water releases flammable gases which may ignite spontaneously 与水接触时释放可燃气体，可自燃。
          Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
          Packing GroupI
          UN Number 2445
          Storage condition Air & Moisture Sensitive 储存温度 2-8°C 储存温度 2-8°C,充氩保存 0-10°C 0-10 2-8°C
          Hazard Codes F,C,N
          Hazard Class4.2/4.3
          Warnings 危化品目录(2015)
          Restrict 危险品
        • ⑴.无色至黄色透明液体，溶液暴露于空气或湿气时易起火。
        • ⑵.用于制备各种烷基、芳基衍生物的有机金属化合物，是生产太阳能电池的原料。
        • ⑶.是重要的锂试剂。与卤代烷和有机化合物中的活性氢交换而将铿原子引入其中，继而可进行许多反应。也用作聚合反应引发剂。
        • ⑷.作为强碱，用于锂-卤交换反应或锂-金属转移金属化反应。
        • ①.作为异丁基锂和叔丁基锂的同类物质，正丁基锂的碱性和反应活性都较差一些，但对于含活泼氢的底物，却是一个有效的脱质子试剂，特别是当形成的是杂原子阴离子或形成的碳阴离子能够被共轭效应稳定（如阴离子在sp
        • 本品（n-C4H9Li）为主要用于有机反应催化剂广泛用于药物中间体，液晶单体，农药及橡胶业的有机催化反应。
        • {ALF} See also N,N,N',N'-Tetramethyl­ethyl­enediamine, A12536.
        • {ALF} Numerous examples of the use of n-BuLi are to be found in Org. Synth. Coll., 7 (1990), 8, (1993), 9 (1998) and in subsequent annual volumes.
        • {ALD} Beilstein: 4,IV,4419
        • {ALF} There are also many examples throughout this catalog. For a useful monograph with many practical procedures, see: B. J. Wakefield, Organolithium Methods, Academic Press, N.Y. (1988).
        • {ALF} Supplied in septum cap bottle.
          • 109-72-8 H12002 n-Butyllithium 正丁基锂

          化学属性

          Flash Point-12°C(lit.)
          TSCAYes
          Boiling Point80 °C
          Solubility剧烈反应
          Melting Point-95 °C
          Stability对空气和湿度敏感
          Appearance liquid
          Density0.67
          Mol. FormulaC4H9Li
          Mol. Weight64.00
          pH-:A
          Danger-Level-
          Redox-

          *以上化合物性质及应用等信息仅供参考