Benzoic acid 苯甲酸

规格: 99%
CAS: 65-85-0
产品编号: H14645
MDL: MFCD00002398
品牌: INFI
Chemical NameBenzoic acid
CAS Number65-85-0
EC Number200-618-2
Beilstein Registry Number636131
MDL NumberMFCD00002398
PubChem Substance ID243
Synonym Benzoic acid {LY} Benzoic acid {} {LY} Benzoic acid {} {} {LY} Benzoic acid {} {} {} {LY} Benzoic acid {} {} {} {} {LY} Benzoic acid {} {} {} {} {} {LY} Benzoic acid {} {} {} {} {} {} {LY} Benzoic acid {} {} {} {} {} {} {} {LY} Benzoic acid {} {} {} {} {} {} {} {} {LY} Benzoic acid {} {} {} {} {} {} {} {} {} {LY} Benzoic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Benzoic acid {} {} {} {} {} {} {} {} {} {} {} {LY} Benzoic acid {} {} {} {} {} {} {} {} {} {} {} {} {LY} Benzoic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Benzoic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Benzoic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Benzoic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Benzoic acid {} {} {} {} {} {} {} {} {} {} {} {}
Reaxys-RN636131
Merck Number1091
Chemical Name Translation苯甲酸
Wiswesser Line NotationQVR
LabNetwork Molecule IDLN00195619
InChIInChI=1S/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9)
Canonical SMILESO=C(O)C1=CC=CC=C1
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1460 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses
   Filiales.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.1-    1849-
   Volume(issue)/page/year: 160,1097,1966

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APYPAY Acta Physiologica Polonica.  (Karger-Libri, POB CH-4009, Warszawa,
   Switzerland) V.1-41, 1950-90.  Volume(issue)/page/year: 12,173,1961

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 17,715,1979

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MMWOAU Muenchener Medicinische Wochenschrift.  (Munich, Fed. Rep. Ger.)
   V.33-115, 1886-1973.  Volume(issue)/page/year: 77,13,1930

TYPE OF TEST

{hazard_

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 10 mmol/L
REFERENCE :
   ZBPIA9 Zentralblatt fuer Bakteriologie, Parasitenkunde,
   Infektionskrankheiten und Hygiene, Abteilung II. Naturwissenschaftliche:
   Allgemeine, Landwirtschaftliche und Technische Mikrobiologie. (Jena, Ger.
   Dem. Rep.)  V.107-132, 1952-77.  Volume(issue)/page/year: 112,226,1959

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 5 mmol/L
REFERENCE :
   PNASA6 Proceedings of the National Academy of Sciences of the United States
   of America.  (National Academy of Sciences, Printing & Pub. Office, 2101
   Constitution Ave., Washington, DC 20418) V.1-    1915-
   Volume(issue)/page/year: 79,1171,1982

WGK Germany1
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H315 Causes skin irritation 会刺激皮肤
  • H318 Causes serious eye damage 严重伤害眼睛
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H372 Causes damage to organs through prolonged or repeated exposure 长期或频繁接触会损伤器官
    RTECSDG0875000
    Precautionary statements
    • P201 Obtain special instructions before use. 使用前获取专门指示。
    • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
    • P203
    • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P264+P265
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
    • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
    • P273 Avoid release to the environment. 避免释放到环境中。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
    • P301+P312
    • P301+P312+P330
    • P301+P317
    • P302+P350
    • P302+P352
    • P302+P352+P332+P313+P362+P364
    • P304+P340
    • P305+P351+P338
    • P305+P351+P338+P310
    • P305+P354+P338
    • P308+P313
    • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
    • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
    • P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医，如果你觉得不舒服
    • P317
    • P318
    • P319
    • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
    • P330 Rinse mouth. 漱口
    • P332+P313
    • P332+P317
    • P337+P313
    • P337+P317
    • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
    • P362+P364
    • P403+P233
    • P405 Store locked up. 上锁保管。
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Danger
      Hazard Codes T,Xi Xn Xi Xn,T
      Safety Statements
      • S22 Do not breathe dust 不要吸入粉尘；
      • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾；
      • S24 Avoid contact with skin 避免皮肤接触；
      • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
      • S36 Wear suitable protective clothing 穿戴适当的防护服；
      • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
      • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
      • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
      • S39 Wear eye/face protection 戴眼睛/面孔保护装置；
      • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
      • S53 Avoid exposure - obtain special instructions before use 避免接触，使用前获得特别指示说明；
      • S63
        Risk Statements
        • R22 Harmful if swallowed 吞咽有害
        • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒
        • R36 Irritating to eyes 刺激眼睛
        • R36/37 Irritating to eyes and respiratory system 对眼睛和呼吸系统有刺激性
        • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
        • R37 Irritating to respiratory system 刺激呼吸道
        • R38 Irritating to skin 刺激皮肤
        • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
        • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
        • R42/43
        • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
        • R45 May cause cancer 可能致癌
        • R48/23
        • R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
          Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
          UN Number UN 3077 9/PG 3 9094
          Storage condition 2-8°C {LY} 2-8°C Store at RT. {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C
        • 碱定量标准。碘定量标准。热值标准。检定铝、硼、铈、铜、铁、铅、锰、汞、镍、硝酸盐、亚硝酸盐、银、钛、钨和钒。测定铝、铜、铁、钛和铀。有机微量分析测定碳、氢、氧和相对分子质量的标准。有机分析中还用于苯甲酰化。用作防腐剂。
        • {ALD} Merck: 14,1091
        • {ALD} Merck: 14,1091
        • Beilstein: 9,92
        • {uni_hamburg} Short: II/2
        • {uni_hamburg} Short: II/27B
        • {MCE} [1]. Nair B, et al. Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate. Int J Toxicol. 2001;20 Suppl 3:23-50.
          • 65-85-0 H14645 Benzoic acid 苯甲酸

          化学属性

          Mol. FormulaC7H6O2
          Mol. Weight122.12
          Boiling Point2479°C at 760 mmHg
          Melting Point121-125 °C
          Density1.08
          Flash Point121°C
          TSCAYes
          Autoignition Point1061 °F
          Vapor Density4.21 (vs air)
          Vapor Pressure10 mmHg ( 132 °C)
          Solubility略溶于水. 0.34 G/100 ML
          Refractive index1.504
          Stability对湿度敏感

          *以上化合物性质及应用等信息仅供参考