L-Pyroglutamic acid L-焦谷氨酸

规格: 99%
CAS: 98-79-3
产品编号: H15518
MDL: MFCD00005272
品牌: INFI
Chemical NameL-Pyroglutamic Acid
CAS Number98-79-3
Alfabeta NamePYROH -
MDL NumberMFCD00005272
EC Number202-700-3
Beilstein Registry Number22,284
Synonym L-Pyroglutamic acid {LY} L-Pyroglutamic acid {} {LY} L-Pyroglutamic acid {} {} {LY} L-Pyroglutamic acid {} {} {} {LY} L-Pyroglutamic acid {} {} {} {} {LY} L-Pyroglutamic acid {} {} {} {} {} {LY} L-Pyroglutamic acid {} {} {} {} {} {} {LY} L-Pyroglutamic acid {} {} {} {} {} {} {} {LY} L-Pyroglutamic acid {} {} {} {} {} {} {} {} {LY} L-Pyroglutamic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Pyroglutamic acid {} {} {} {} {} {} {} {} {} {} {LY} L-Pyroglutamic acid {} {} {} {} {} {} {} {} {} {} {} {LY} L-Pyroglutamic acid {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Pyroglutamic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Pyroglutamic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Pyroglutamic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Pyroglutamic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
PubChem Substance ID7405
Merck Number8001
Chemical Name TranslationL-焦谷氨酸
Reaxys-RN82132
LabNetwork Molecule IDLN00196118
InChIInChI=1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m0/s1
Canonical SMILESO=C(O)[C@H](CC1)NC1=O
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4882359

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4882359

Warnings IRRITANT
Signal word Warning
WGK Germany3
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
  • S37 Wear suitable gloves 戴适当手套；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
    Risk Statements
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      Precautionary statements
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P305+P351+P338
      • P332+P313
      • P305+P351+P338+P337+P313
      • P302+P350
      • P337+P313
      • P302+P352+P332+P313+P362+P364
        Hazard statements
        • H315 Causes skin irritation 会刺激皮肤
        • H319 Causes serious eye irritation 严重刺激眼睛
        • H335 May cause respiratory irritation 可能导致呼吸道刺激
          Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
          RTECSTW3710000
          Hazard Codes Xi
          Storage condition 2-8°C {LY} 2-8°C Store at RT. {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C
        • 非对称合成砌块。
        • {ALF} Resolving agent for chiral bases: Helv. Chim. Acta, 41, 181 (1958). Versatile chiral starting material:
        • {ALF} Reduction to the alcohol followed by reaction with benzaldehyde gives a bicyclic lactam which is a useful chiral synthon: J. Org. Chem., 51, 3140 (1986); Tetrahedron Lett., 32, 1379 (1991):
        • {uni_hamburg} Short: EINECS
        • {ALF} For use in an efficient synthesis of quinolizidine and indolizidine alkaloids, see: J. Org. Chem., 60, 717 (1995).
        • {ALD} Merck: 14,8001
        • {ALD} Merck: 14,8001
        • Beilstein:22,284
        • {uni_hamburg} Short: III/5a
          • 98-79-3 H15518 L-Pyroglutamic acid L-焦谷氨酸

          化学属性

          Mol. FormulaC5H7NO3
          Mol. Weight129.11
          Density1.38
          Melting Point155-162°C
          TSCAYes
          Solubility10-15 G/100 ML (20 ºC)
          Appearance 无色结晶。熔点162-163℃，溶于水、醇、丙酮和冰醋酸，微溶于乙酸乙酯，不溶于醚。
          Refractive index-10 ° (C=5, H2O)
          Boiling Point239.15 °C at 760 mmHg

          *以上化合物性质及应用等信息仅供参考