1-Butanol 正丁醇

规格: 99%
CAS: 71-36-3
产品编号: H22122
MDL: MFCD00002964
品牌: INFI
Chemical Name1-Butanol
Synonym 1-丁醇 丁醇 正丁醇 1-丁醇,丁醇,丙原醇,第一丁醇,酪醇 Alcool butylique Butan-1-ol Butanol-(1) Butylalkohol Butylowy alkohol Hemostyp Propylcarbinol n-Butanol n-Butanol, Butyl alcohol n-Butanol, Butyl alcohol prim.-n-Butylalkohol 丁醇 正丁醇
CAS Number71-36-3
PubChem Substance ID87563705
EC Number200-751-6
Beilstein Registry Number969148
MDL NumberMFCD00002964
Reaxys-RN969148
Merck Number1540
Chemical Name Translation正丁醇
Wiswesser Line NotationQ4
LabNetwork Molecule IDLN00164428
InChIInChI=1S/C4H10O/c1-2-3-4-5/h5H,2-4H2,1H3
GHS Symbol
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Human
DOSE/DURATION           : 25 ppm
TOXIC EFFECTS :
   Sense Organs and Special Senses (Olfaction) - effect, not otherwise
   specified
   Sense Organs and Special Senses (Eye) - conjunctive irritation
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher information, see AEHLAU.
   Volume(issue)/page/year: 25,282,1943

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Gastrointestinal - other changes
   Blood - hemorrhage
REFERENCE :
   COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences.
   (Paris, France)  V.1-261, 1835-1965.  For publisher information, see CRASEV.
    Volume(issue)/page/year: 81,192,1875

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 310 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EVHPAZ EHP, Environmental Health Perspectives.  (U.S. Government Printing
   Office, Supt of Documents, Washington, DC 20402)  No.1-    1972-
   Volume(issue)/page/year: 61,321,1985

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 3484 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - corneal damage
   Cardiac - pulse rate
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   IMSUAI Industrial Medicine and Surgery.  (Northbrook, IL)  V.18-42, 1949-73.
    For publ

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Mold - Aspergillus nidulans
DOSE/DURATION           : 7000 ppm
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 215,187,1989

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 100 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 182,135,1987

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 35295 mg/kg
SEX/DURATION            : female 1-15 day(s) after conception
TOXIC EFFECTS :

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 35295 mg/kg
SEX/DURATION            : female 1-15 day(s) after conception
TOXIC EFFE

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 6000 ppm/7H
SEX/DURATION            : female 1-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   12,469,1989

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 35295 mg/kg
SEX/DURATION            : female 1-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Effects on Newborn - biochemical and metabolic
REFERENCE :
   ONGZAC Ontogenez (Moscow).  For English translation, see SJDBA9.  (V/O
   Mezhdunarodnaya Kniga, 113095, Moscow, USSR)  V.1-  1970-
   Volume(issue)/page/year: 22(1),71,1991

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 8000 ppm/7H
SEX/DURATION            : female 1-19 day(s) after conception
TOXI

TYPE

WGK Germany1
Hazard Codes 3
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H315 Causes skin irritation 会刺激皮肤
  • H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
  • H302 Harmful if swallowed 吞食有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H318 Causes serious eye damage 严重伤害眼睛
    Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
    RTECSEO1400000
    Precautionary statements
    • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
    • P233 Keep container tightly closed. ?保持容器密闭。
    • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
    • P241+P242+P243
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
    • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
    • P301+P310+P331+P330
    • P301+P312
    • P302+P352
    • P302+P352+P332+P313+P362+P364
    • P303+P361+P353
    • P304+P340
    • P304+P340+P312
    • P305+P351+P338
    • P305+P351+P338+P310
    • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
    • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
    • P313 Get medical advice/attention. 获取医疗咨询/就医
    • P332+P313
    • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
    • P370+P378
    • P403+P233
    • P405 Store locked up. 上锁保管。
    • P420 Store away from other materials. 远离其他材料。
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Danger
      Safety Statements
      • S13 Keep away from food, drink and animal foodstuffs 远离食品、饮料和动物饲料保存;
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
      • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
      • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
      • S46 If swallowed, seek medical advice immediately and show this container or label 食入时,立即求医并出示容器/标签;
      • S7/9 Keep container tightly closed and in a well-ventilated place 保持容器严格密闭,置于通风良好的场所;
        Risk Statements
        • R10 Flammable 易燃
        • R22 Harmful if swallowed 吞咽有害
        • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
        • R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
        • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
        • R67 Vapours may cause drowsiness and dizziness 蒸汽可能导致嗜睡和昏厥
          UN Number 1120
          Storage condition 密封阴凉干燥保存。 Hygroscopic
          Packing GroupIII
          Hazard Class3
          Warnings 危化品目录(2015)
          Restrict 危险品
        • 作为溶剂用以分离高氯酸钾及高氯酸钠,也可分离氯化钠及氯化锂。用以洗涤乙酸铀酰锌钠沉淀。比色测定中钼酸盐法测定砷酸时用。测定牛乳中的脂肪,皂化酯类的介质。显微分析时制备石蜡包埋物质。用作脂肪、蜡、树脂、虫胶、树胶等的溶剂。
        • 分子生物学级正丁醇用在经CsCl梯度离心纯化的DNA中去除溴化乙锭。
        • {uni_hamburg} Short: II/27B
        • {uni_hamburg} Short: II/5
        • {ALD} Merck: 14,1540
        • {ALD} Merck: 14,1540
        • Beilstein: 1,IV,1506
        • 71-36-3 H22122 1-Butanol
正丁醇

          化学属性

          Refractive index1.3980 to 1.4000
          Boiling Point116-118
          Melting Point-89
          Flash Point37°C(lit.)
          TSCAYes
          Autoignition Point649 °F
          Vapor Density2.55 (vs air)
          Vapor Pressure5 (4 mmHg) at 20 °C hPa
          Solubility80 G/L (20 ºC)
          Stability对湿度敏感
          Mol. FormulaCH3(CH2)3OH
          Mol. Weight74
          Density0.81

          *以上化合物性质及应用等信息仅供参考