| Chemical Name | Diisobutylaluminium hydride |
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| CAS Number | 1191-15-7 |
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| EC Number | 214-729-9 |
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| Beilstein Registry Number | 4123663 |
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| MDL Number | MFCD00008928 |
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| Synonym |
氫化二異丁基鋁
DIBAL-H
Al-Alchili
二异丁基氢化铝, 25%甲苯溶液
Aluminum, diisobutylhydro-
DIISOBUTYLALUMINUM HYDRIDE
Bis(isobutyl)hydroaluminum
二异丁基氢化铝, 20% (CA 1M) SOLN. IN TOLUENE
氢化二异丁基铝
hydrobis(2-methylpropyl)-aluminu
hydrobis(2-methylpropyl)-Aluminum
DIBAL-H;DIBAL
Aluminum, hydrodiisobutyl-
DIISOBUTYLALUMINIUM HYDRIDE
Aluminum, hydrobis(2-methylpropyl)-
DIBAH
二异丁基氢化铝 溶液
Diisobutylhydroaluminum
DIBAL-H DIBAL
hydrobis(2-methylpropyl)aluminum
二异丁基氢化铝
DI-I-BUTYLALUMINUM HYDRIDE
Diisobutylaluminum
二异丁基氢化铝, 1M SOLUTION IN HEXANE |
| PubChem Substance ID | 24852856 |
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| Chemical Name Translation | 二异丁基氢化铝 |
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| Wiswesser Line Notation | 1Y1&1-AL-H1Y1&1 |
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| Signal word |
Danger |
GHS Symbol
| WGK Germany | 2 |
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| Safety Statements | |
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- S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S27 Take off immediately all contaminated clothing 立即脱掉全部污染的衣服；
- S29 Do not empty into drains 不要排入下水道；
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- S43 In case of fire use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add -?Never use water) 着火时使用（指明具体的消防器材种类，如果用水增加危险，注明“禁止用水”
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- S46 If swallowed, seek medical advice immediately and show this container or label 食入时，立即求医并出示容器/标签；
- S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
- S62 If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label where possible 吞食后不要催吐：立即求医并出示该容器或标签；
- S7/8 Keep container tightly closed and dry 保存在严格密闭容器中，保持干燥；
- S9 Keep container in a well-ventilated place 保持容器在通风良好的场所；
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| Risk Statements | |
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- R11 Highly flammable 非常易燃
- R14 Reacts violently with water 遇水会猛烈反应
- R14/15 Reacts violently with water, liberating extremely flammable gases 遇水剧烈反应，释放出高度可燃气体
- R17 Spontaneously flammable in air 在空气中能够自燃
- R19 May form explosive peroxides 可能生成易爆的过氧化物质
- R34 Causes burns 会导致灼伤
- R35 Causes severe burns 会导致严重灼伤
- R37 Irritating to respiratory system 刺激呼吸道
- R48/20
- R51/53
- R62 Possible risk of impaired fertility 有削弱生殖能力的危险
- R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
- R65 Harmful: may cause lung damage if swallowed 若吞咽可能伤害肺部器官
- R67 Vapours may cause drowsiness and dizziness 蒸汽可能导致嗜睡和昏厥
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| Precautionary statements | |
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- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P231+P232
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P273 Avoid release to the environment. 避免释放到环境中。
- P422 Store contents under… 存储目录在…之下。
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| Hazard statements | |
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- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
- H304 May be fatal if swallowed and enters airways 吞食和进入呼吸道可能致命
- H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
- H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
- H261 In contact with water releases flammable gas 与水接触时释放可燃气体。
- H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
- H250 Catches fire spontaneously if exposed to air 暴露于空气自发着火
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H351 Suspected of causing cancer 怀疑致癌
- H260 In contact with water releases flammable gases which may ignite spontaneously 与水接触时释放可燃气体，可自燃。
- H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
- H361d Suspected of damaging the unborn child 怀疑对未出生婴儿造成伤害
- H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
- H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
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| Personal Protective Equipment |
Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US)
Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
| Packing Group | I |
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| UN Number |
3399 |
| Storage condition |
Moisture Sensitive
易吸潮，密封充氩保存
Air & Moisture Sensitive
充氩保存
2-8°C |
| RTECS | BD0710000 |
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| Hazard Codes |
4.3
F,C |
| Hazard Class | 4.3 |
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TYPE OF TEST : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 70 gm/m3/1H
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes
REFERENCE :
MELAAD Medicina del Lavoro. Industrial Medicine. (Via S. Barnaba, 8, 20122
Milan, Italy) V.16- 1925- Volume(issue)/page/year: 57,188,1966
| Warnings |
危化品目录(2015) |
| Restrict |
危险品 |
⑴.无色液体，高度易燃。引起严重灼伤。吞食可能造成肺部损伤。蒸汽可能引起困倦和眩晕。
⑵.主要用作精细化学品的还原剂和氢铝化剂。
⑶.具有强烈的吸湿性，对空气和湿气敏感，遇水会发生激烈反应放出氢气。
⑷.四氢呋喃不适宜作溶剂，因为两者反应生成配位化合物。二异丁基氢化铝是一种新型金属有机化合物，可使酮、羧酸、酯选择性还原成相应的醛或者醇。
Used in Pd-catalyzed reductive debromination of secondary alkyl bromides. O-Debenzylation and ring opening of perbenzylated furanosides. Convenient in situ generation of HZrCp2Cl from ZrCp2Cl2 and DIBAL-H.
{ALD} Merck: 14,10425
{ALF} Reduces chiral ɑ-silyloxy esters to the corresponding enantiomerically-pure hydroxy aldehydes: J. Chem. Soc., Chem. Commun., 2475 (1995).
{ALD} Merck: 14,10425
Beilstein:4(4)4400
