Benzene 苯

规格: 99%, SpcDry, Water≤50 ppm (by K.F.), SpcSeal
CAS: 71-43-2
产品编号: H33936
MDL: MFCD00003009
品牌: INFI
Chemical NameBenzene
CAS Number71-43-2
PubChem Substance ID87563234
EC Number200-753-7
Beilstein Registry Number969212
MDL NumberMFCD00003009
Reaxys-RN969212
Merck Number1066
Synonym Fenzen C6H6 (benzene) Bicarburet of hydrogen Phenyl hydride (6)Annulene [6]Annulene {uni_hamburg} 苯 溶液 NCI-C55276 Nitration benzene Benzolene Phene benzene Benzene II RCRA waste number U019 苯, 99% Cyclohexatriene Coal naphtha Benzene Motor benzol 安息油,净苯,动力苯,纯苯,溶液苯,困净苯 Benzolo Benzene I Benzene anhydrous Benzine 苯标准溶液 Mineral naphtha 苯 1,3,5-Cyclohexatriene Benzol Benzeen 苯纯度分析标准物质 Benzen Pyrobenzol Benzole Benzin 苯,安息油,净苯,动力苯,纯苯,溶液苯,困净苯 Carbon oil Benzin (Obs.) Pyrobenzole 苯标准溶液;安息油;净苯;动力苯;纯苯;溶液苯;困净苯 Benzine (Obs.) 气相色谱仪检定用标准物质,苯-甲苯溶液
Chemical Name Translation苯(易涉毒)
Wiswesser Line NotationRH
LabNetwork Molecule IDLN00164622
InChIInChI=1S/C6H6/c1-2-4-6-5-3-1/h1-6H
GHS Symbol
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Human
DOSE/DURATION           : 10 ppm/8H/10Y-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Blood - leukemia
REFERENCE :
   TRBMAV Texas Reports on Biology and Medicine.  (Galveston, TX)  V.1-41(2),
   1943-81/82.

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 670 mg/kg/19W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Blood - leukemia
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   KLWOAZ Klinische Wochenscrift.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.1-    1922-  Volume(issue)/page/year:

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1200 mg/kg/8W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   82,19,1986

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2400 mg/kg/8W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   82,19,1986

{

TYPE O

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Human
DOSE/DURATION           : 2 pph/5M
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TABIA2 Tabulae Biologicae.  (The Hague, Netherlands)  V.1-22, 1925-63.
   Discontinued.  Volume(issue)/page/year: 3,231,1933

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 20000 ppm/5M
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 138,65,1928

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 930 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   7,767,1965

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 150 ppm/1Y-I
TOXIC EFFECTS :
   Blood - other changes
   Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
   BLUTA9 Blut.  (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way,
   Secaucus, NJ 07094) V.1-    1955-  Volume(issue)/page

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECI

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 62500 ug/L
REFERENCE :
   PMRSDJ Progress in Mutation Research.  (Elsevier Science Pub. Co., Inc., 52
   Vanderbilt Ave., New York, NY 10017)  V.1-    1981- Volume(issue)/page/year:
   5,587,1985

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 39060 ug/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 298,81,1992

TYPE OF TEST            : DNA inhibiti

{haz

TYPE OF TEST            : Mutation in microorganisms
TES

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 1 mg/L
REFERENCE :
   BZARAZ Biologicheskii Zhurnal Armenii.  Biological Journal of Armenia. (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.19-    1966-
   Volume(issue)/page/year: 26(12),38,1973

TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 275 mg/L
REFERENCE :
   PMRSDJ Progress in Mutation Research.  (Elsevier Science Pub. Co., Inc., 52
   Vanderbilt Ave., New York, NY 10017)  V.1-    1981- Volume(issue)/page/year:
   5,271,1985

TYPE OF TEST            :

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Inhalation
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 1 ppm/6H
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 8,29,1986

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Unreported

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 12 gm/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 19,41A,1979

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 50 ppm/24H
SEX/DURATION            : female 7-14 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - extra-embryonic structures
   (e.g., placenta, umbilical cord)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   JHEMA2 Journal of Hygiene, Epidemiology, Microbiology, and Immunology.
   (Avicenum, Malostranske namesti 28, 11802 Prague 1, Czechoslovakia)  V.1-
   1957-  Volume(issue)/page/year: 24,363,1980

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 219 mg/kg
SEX/DURATION            : female 14 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - blood and lymphatic
   systems (including spleen and marrow)
   Reproductive - Specific Developmental Abnormalities - hepatobiliary system
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   18,1,1991

TYPE OF TEST            :

WGK Germany3
Hazard Codes 3 F,T F;T
Hazard statements
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H315 Causes skin irritation 会刺激皮肤
  • H304 May be fatal if swallowed and enters airways 吞食和进入呼吸道可能致命
  • H350 May cause cancer 可能致癌
  • H340 May cause genetic defects 可能导致遗传性缺陷
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H372 Causes damage to organs through prolonged or repeated exposure 长期或频繁接触会损伤器官
  • H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
    Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
    RTECSCY1400000
    Precautionary statements
    • P201 Obtain special instructions before use. 使用前获取专门指示。
    • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
    • P233 Keep container tightly closed. ?保持容器密闭。
    • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
    • P241+P242+P243
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
    • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
    • P273 Avoid release to the environment. 避免释放到环境中。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P301+P310
    • P301+P310+P331+P330
    • P302+P352+P332+P313+P362+P364
    • P303+P361+P353
    • P304+P340+P312
    • P305+P351+P338
    • P305+P351+P338+P337+P313
    • P308+P311
    • P308+P313
    • P331 Do NOT induce vomiting.. 不要催吐。
    • P332+P313
    • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
    • P370+P378
    • P403+P233
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Danger
      Storage condition 易吸潮,密封充氩保存 0-6°C 储存温度2-8℃ <;0 <0°C 避光贮存
      UN Number 1114 UN1114
      Risk Statements
      • R11 Highly flammable 非常易燃
      • R14/15 Reacts violently with water, liberating extremely flammable gases 遇水剧烈反应,释放出高度可燃气体
      • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
      • R45 May cause cancer 可能致癌
      • R46 May cause inheritable genetic damage 可能引起遗传基因损害
      • R48/23/24/25
      • R65 Harmful: may cause lung damage if swallowed 若吞咽可能伤害肺部器官
        Safety Statements
        • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
        • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
          Packing GroupII
          Hazard Class3
          Warnings 危化品目录(2015)
          Restrict -
        • 脂肪、树脂和碘等的溶剂。测定矿物折射指数,有机合成,光学纯溶剂。
        • {SA} Merck 14 ,1066
        • {ALD} Merck: 14,1066
        • {ALD} Merck: 14,1066
        • Beilstein: 5,IV,583
        • {uni_hamburg} Short: II/19a
        • {uni_hamburg} Short: II/19b
        • 71-43-2 H33936 Benzene
苯

          化学属性

          Mol. FormulaC6H6
          Mol. Weight78
          Refractive index1.4990 to 1.5020
          Boiling Point80
          Density0.874
          Melting Point5.5
          Flash Point-10°C(lit.)
          TSCAYes
          Autoignition Point1043 °F
          Vapor Density2.77 (vs air)
          Vapor Pressure166 mmHg ( 37.7 °C)
          Solubility0.18 G/100 ML
          Stability易吸潮
          Danger-Level-
          pH-:-
          Redox-

          *以上化合物性质及应用等信息仅供参考