1,4,8,11-Tetraazacyclotetradecane 1,4,8,11-四氮杂环十四烷

规格: 98%
CAS: 295-37-4
产品编号: H46070
MDL: MFCD00005105
品牌: INFI
Chemical Name1,4,8,11-Tetraazacyclotetradecane
CAS Number295-37-4
Synonym 1,1',1''-(1,4,8,11-Tetraazacyclotetradecane-1,4,8-triyl)tris[2,2,2-trifluoro-ethanone 1,4,8,11-TETRAAZACYCLOTETRADECANE(CYCLAM) 1,4,8,11-TETRAAZACYCLOTETRADECANE, 98+% 1,4,8,11-Tetraazacyclotetradecane 98% 1,4,8,11-四叠氮环十四烷 1,4,8,11-四氮杂环十四烷 1,4,8,11-四氮环十四烷 1,4,8,11-四氮环十四烷, 98+% 1,4,8-Tris(trifluoroacetyl)-1,4,8,11-tetraazacyclo 1,4,8-Tris(trifluoroacetyl)-1,4,8,11-tetraazacyclotetradecane CYCLAM Cyclam Cyclam, 98+% Cyclam=1,4,8,11-Tetraazacyclotetradecane JM 1498 jm1498
EC Number206-039-1
Beilstein Registry Number111811
MDL NumberMFCD00005105
PubChem Substance ID64964
Alfabeta NameTETRAAZACYCLOTETRADECANE 14811-,,,
Reaxys-RN111811
Chemical Name Translation1,4,8,11-四氮杂环十四烷
InChIKeyMDAXKAUIABOHTD-UHFFFAOYSA-N
LabNetwork Molecule IDLN00184756
InChIInChI=1S/C10H24N4/c1-3-11-7-9-13-5-2-6-14-10-8-12-4-1/h11-14H,1-10H2
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 371 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Skin and Appendages - primary irritation (after topical exposure)
REFERENCE :
   CMSHAF Chemosphere.  (Pergamon Press Inc., Maxwell House, Fairview Park,
   Elmsford, NY 10523) V.1-    1972-  Volume(issue)/page/year: 17,839,1988

Signal word Warning
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S37 Wear suitable gloves 戴适当手套；
    Risk Statements
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      Precautionary statements
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P302+P352+P332+P313+P362+P364
      • P305+P351+P338
      • P305+P351+P338+P337+P313
      • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
        Hazard statements
        • H315 Causes skin irritation 会刺激皮肤
        • H319 Causes serious eye irritation 严重刺激眼睛
        • H335 May cause respiratory irritation 可能导致呼吸道刺激
          RTECSXA5254800
          Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
          Storage condition Air Sensitive
          Hazard Codes Xi
          Warnings IRRITANT
        • Reagent used in the preparation of Plerixafor derivatives.
        • {ALF} The Ni(II) complex catalyzes the novel electrochemical reaction of epoxides with carbon dioxide to give good yields of cyclic carbonates: J. Chem. Soc., Chem. Commun., 43 (1995). A similar system catalyzes the electrochemical intramolecular reductive cyclization of a series of o-halogenated aryl alkenes: Tetrahedron Lett., 36, 4429 (1995):
        • {ALF} For use in synthesis of molecules with electroactive cavities, see (Ferrocenyl­methyl)­trimethyl­ammonium iodide, 39399.
        • {ALF}
        • {ALF} Nitrogen analogue of the crown ethers (see Appendix 2), forming stable complexes with metal ions: Inorg. Chem., 4,1102, 1109 (1965); Can. J. Chem., 48, 1481 (1970). For examples
        • {uni_hamburg} Short: III/35B
        • {uni_hamburg} Short: IV/20C
        • {ALF} Complex with iron(II) triflate is an effective epoxidation catalyst: J. Am. Chem. Soc., 113, 7052 (1991).
        • {uni_hamburg} Short: EINECS
        • {ALF} Nitrogen analogue of the crown ethers (see Appendix 2), forming stable complexes with metal ions: Inorg. Chem., 4,1102, 1109 (1965); Can. J. Chem., 48, 1481 (1970). For examples of use as a versatile ligand in coordination chemistry, see: Acc. Chem. Res., 11, 392 (1978); J. Chem. Soc., Chem. Commun., 1322 (1986); 1075 (1987); 156 (1988); Inorg. Chem., 26, 908 (1987); J. Am. Chem. Soc., 110, 3679 (1988).
        • {TRC} Jacobson, O., et al.: Bioorg. Med. Chem., 17, 1486 (2009),
          • 295-37-4 H46070 1,4,8,11-Tetraazacyclotetradecane 1,4,8,11-四氮杂环十四烷

          化学属性

          Mol. FormulaC10H24N4
          Mol. Weight200
          Density1.422
          Melting Point185-188
          TSCANo
          Stability对湿度敏感

          *以上化合物性质及应用等信息仅供参考