1,3-Butanediol 1,3-丁二醇

规格: 99%
CAS: 107-88-0
产品编号: H57283
MDL: MFCD00004554
品牌: INFI
Chemical Name1,3-Butanediol 1,3-丁二醇
Synonym 1,3-Butanediol {LY} 1,3-Butanediol 1,3-butanediol 1,3-butylene glycol 1,3-butylene glycol, (14)C-labeled 1,3-butylene glycol, (DL)-isomer 1,3-butylene glycol, (R)-isomer 1,3-butylene glycol, (S)-isomer butylene glycol {} {LY} 1,3-Butanediol {} {} {LY} 1,3-Butanediol {} {} {} {LY} 1,3-Butanediol {} {} {} {} {LY} 1,3-Butanediol {} {} {} {} {} {LY} 1,3-Butanediol {} {} {} {} {} {} {LY} 1,3-Butanediol {} {} {} {} {} {} {} {LY} 1,3-Butanediol {} {} {} {} {} {} {} {} {LY} 1,3-Butanediol {} {} {} {} {} {} {} {} {} {LY} 1,3-Butanediol {} {} {} {} {} {} {} {} {} {} {LY} 1,3-Butanediol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,3-Butanediol {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,3-Butanediol {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,3-Butanediol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
CAS Number107-88-0
EC Number203-529-7
Beilstein Registry Number1718945
MDL NumberMFCD00004554
Reaxys-RN1718945
Merck Number1567
PubChem Substance ID7896
Chemical Name Translation1,3-丁二醇
Wiswesser Line NotationQY1&2Q
LabNetwork Molecule IDLN00163083
InChIInChI=1S/C4H10O2/c1-4(6)2-3-5/h4-6H,2-3H2,1H3
Canonical SMILESCC(O)CCO
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 18610 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher information, see AEHLAU.
   Volume(issue)/page/year: 23,259,1941

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 12980 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 45,669,1956

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 20 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National
   Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair
   Memorial Laboratory, Lehig

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 11 gm/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Gastrointestinal - other changes
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher information, see AEHLAU.
   Volume(issue)/page/year: 23,259,1941

TYPE OF TEST

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 42360 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 5(4),189,1986

WGK Germany1
Personal Protective Equipment Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US) Eyeshields, Gloves
RTECSEK0440000
Signal word Warning
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
  • P242 Use only non-sparking tools. 只能使用无火花工具。
  • P243 Take precautionary measures against static discharge. 采取预防措施，防止静电放电。
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P303+P361+P353
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P337+P313
  • P370+P378
  • P403+P235
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
    Hazard statements
    • H226 Flammable liquid and vapour 易燃液体和蒸气
    • H319 Causes serious eye irritation 严重刺激眼睛
      Storage condition 2-8°C {LY} 2-8°C Hygroscopic Store at room temperature {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
      Safety Statements
      • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
      • S36 Wear suitable protective clothing 穿戴适当的防护服；
        Risk Statements
        • R36 Irritating to eyes 刺激眼睛
        • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
        • 1,3-丁二醇具有二元醇的反应性、无臭、低毒、水溶性好等特点，主要用于有机合成，是聚酯树酯、醇酸树脂的原料，增塑剂的原料，聚氨酯涂料的原料，湿润剂和柔软剂，医药、染料的中间体。
        • {MCE} [2]. R B Tobin,et al. Nutritional and metabolic studies in humans with 1,3-butanediol. Fed Proc. 1975 Nov;34(12):2171-6.
        • {ALD} Merck:14,1567
        • {ALD} Merck:14,1567
        • Beilstein: 1,IV,2508
        • {uni_hamburg} Short: II/19b
        • {uni_hamburg} Short: II/27B
        • {MCE} [1]. C Marie, et al. Protective action of 1,3-butanediol in cerebral ischemia. A neurologic, histologic, and metabolic study. J Cereb Blood Flow Metab. 1987 Dec;7(6):794-800.
        • {MCE} [1]. C Marie, et al. Protective action of 1,3-butanediol in cerebral ischemia. A neurologic, histologic, and metabolic study. J Cereb Blood Flow Metab. 1987 Dec;7(6):794-800.
        • {MCE} [2]. R B Tobin,et al. Nutritional and metabolic studies in humans with 1,3-butanediol. Fed Proc. 1975 Nov;34(12):2171-6.
          • 107-88-0 H57283 1,3-Butanediol 1,3-丁二醇

          化学属性

          Mol. FormulaC4H10O2
          Mol. Weight90.12
          Density1.005
          Refractive index1.4390 to 1.4410
          Boiling Point203-204 °C at 760 mmHg
          Flash Point122°C(lit.)
          TSCAYes
          Melting Point-54 °C
          Solubility微溶于乙醚，易溶于水，易溶于乙醇。
          Vapor Density3.1 (20 °C, vs air)
          Vapor Pressure0.06 mmHg ( 20 °C)
          Autoignition Point741 °F
          Stability易吸潮

          *以上化合物性质及应用等信息仅供参考