cis-4-Hydroxy-L-proline 羟脯氨酸

规格: 97%
CAS: 618-27-9
产品编号: H62992
MDL: MFCD00064319
品牌: INFI
Chemical NameCis-4-Hydroxy-L-Proline
CAS Number618-27-9
Synonym cis-4-Hydroxy-L-proline {LY} cis-4-Hydroxy-L-proline {} {LY} cis-4-Hydroxy-L-proline {} {} {LY} cis-4-Hydroxy-L-proline {} {} {} {LY} cis-4-Hydroxy-L-proline {} {} {} {} {LY} cis-4-Hydroxy-L-proline {} {} {} {} {} {LY} cis-4-Hydroxy-L-proline {} {} {} {} {} {} {LY} cis-4-Hydroxy-L-proline {} {} {} {} {} {} {} {LY} cis-4-Hydroxy-L-proline {} {} {} {} {} {} {} {} {LY} cis-4-Hydroxy-L-proline {} {} {} {} {} {} {} {} {} {LY} cis-4-Hydroxy-L-proline {} {} {} {} {} {} {} {} {} {} {LY} cis-4-Hydroxy-L-proline {} {} {} {} {} {} {} {} {} {} {} {LY} cis-4-Hydroxy-L-proline {} {} {} {} {} {} {} {} {} {} {} {} {LY} cis-4-Hydroxy-L-proline {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} cis-4-Hydroxy-L-proline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} cis-4-Hydroxy-L-proline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} cis-4-Hydroxy-L-proline {} {} {} {} {} {} {} {} {} {} {} {} {} {
EC Number210-542-1
Beilstein Registry Number81440
MDL NumberMFCD00064319
PubChem Substance ID440015
Chemical Name Translation顺式-4-羟基-L-脯氨酸
Reaxys-RN81440
Merck Number4840
LabNetwork Molecule IDLN00335236
InChIInChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4-/m0/s1
Canonical SMILESO=C(O)[C@H](C1)NC[C@H]1O
GHS Symbol
Signal word Danger
WGK Germany3
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
    Risk Statements
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      Precautionary statements
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
      • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P301+P312
      • P302+P352
      • P304+P312
      • P304+P340
      • P305+P351+P338
      • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
      • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
      • P322 Specific measures (see …on this label). 具体治疗（见本标签上的）。
      • P330 Rinse mouth. 漱口
      • P332+P313
      • P337+P313
      • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
      • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
      • P403+P233
      • P405 Store locked up. 上锁保管。
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
        Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
        Storage condition 2-8°C {LY} 2-8°C Store at RT. {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C
        Hazard statements
        • H302 Harmful if swallowed 吞食有害
        • H312 Harmful in contact with skin 皮肤接触有害
        • H315 Causes skin irritation 会刺激皮肤
        • H319 Causes serious eye irritation 严重刺激眼睛
        • H332 Harmful if inhaled 吸入有害
        • H335 May cause respiratory irritation 可能导致呼吸道刺激
        • Amanita sp.多肽毒素的组成部分，但不像胶原蛋白那样，它不属于动物蛋白
        • {MCE} [2]. Kao WW, et, al. Proline analogue removes fibroblasts from cultured mixed cell populations. Nature. 1977 Mar 3;266(5597):63-4.
        • {MCE} [3]. Tan EM, et, al. Proline analogues inhibit human skin fibroblast growth and collagen production in culture. J Invest Dermatol. 1983 Apr;80(4):261-7.
        • {MCE} [4]. Riley DJ, et, al. Prevention of bleomycin-induced pulmonary fibrosis in the hamster by cis-4-hydroxy-l-proline. Am Rev Respir Dis. 1981 Apr;123(4 Pt 1):388-93.
        • {TRC} Lawrence, C., et al.: Biochem. J., 313, 185 (1996),
        • {ALD} Merck: 14,4840
        • {ALD} Merck: 14,4840
        • Beilstein:22(5)5,7
        • {MCE} [1]. Lewko WM, et, al. Sensitivity of N-nitrosomethylurea-induced rat mammary tumors to cis-hydroxyproline, an inhibitor of collagen production. Cancer Res. 1981 Jul;41(7):2855-62.
        • {MCE} [1]. Lewko WM, et, al. Sensitivity of N-nitrosomethylurea-induced rat mammary tumors to cis-hydroxyproline, an inhibitor of collagen production. Cancer Res. 1981 Jul;41(7):2855-62.
        • {MCE} [2]. Kao WW, e
          • 618-27-9 H62992 cis-4-Hydroxy-L-proline 羟脯氨酸

          化学属性

          Mol. FormulaC5H9NO3
          Mol. Weight131.13
          Density1.422
          Melting Point257°C
          TSCAYes
          Solubility可溶
          Refractive index-59 ° (C=2, H2O)
          Boiling Point355.2°C at 760 mmHg

          *以上化合物性质及应用等信息仅供参考