2-Methoxyethanol 2-甲氧基乙醇

规格: 99%, SpcDry, with molecular sieves, Water≤50 ppm (by K.F.), SpcSeal
CAS: 109-86-4
产品编号: H63857
MDL: MFCD00002867
品牌: INFI
Chemical NameEthylene glycol monomethyl ether
Synonym 2-Methoxy-aethanol 2-Methoxyethanol 2-Metossietanolo Aethylenglykol-monomethylaether Dowanol 7 Dowanol EM Ethylene glycol methyl ether Ethylene glycol monomethyl ether Ethylene glycol monomethyl ether; Methyl cellosolve; Methyl glycol Glycol ether EM Glycol monomethyl ether Glycolmethyl ether Methoxyhydroxyethane Methyl cellosolve Methyl ethoxol Methyl glycol Methyl oxitol Methylglykol Metil cellosolve Metoksyetylowy alkohol Monomethyl ether of ethylene glycol Poly-Solv EM Prist 乙二醇单甲醚 甲基乙二醇 甲基溶纤剂®
CAS Number109-86-4
PubChem Substance ID8019
EC Number203-713-7
Beilstein Registry Number1731074
MDL NumberMFCD00002867
Chemical Name Translation乙二醇单甲醚
InChIKeyXNWFRZJHXBZDAG-UHFFFAOYSA-N
Wiswesser Line NotationQ2O1
LabNetwork Molecule IDLN00163735
Reaxys-RN1731074
Merck Number6038
InChIInChI=1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National
   Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair
   Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015)
   Volume(issue)/page/year: 1,57,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1280 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National
   Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair
   Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015)
   Volume(issue)/page/year: 1,57,1974

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 3380 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - gastritis
   Liver - other changes
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher information, see AEHLAU.
   Volume(is

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 3380 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - gastritis
   Liver - other changes
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 150 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 320,125,1994

TYPE OF TEST            : Sperm Morphology
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 500 mg/kg
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 6,390,1984

TYPE OF TEST            : Dominant lethal test
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 500 mg/kg
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 6,390,1984

TYPE OF TEST            : Sperm Morphology
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 6,390,1984

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 175 mg/kg
SEX/DURATION            : female 7-13 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - parturition
   Reproductive - Effects on Newborn - biochemical and metabolic
REFERENCE :
   DCTODJ Drug and Chemical Toxicology.  (Marcel Dekker, 270 Madison Ave., New
   York, NY 10016) V.1-    1977/78-  Volume(issue)/page/year: 9,1,1986

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 100 ppm/6H
SEX/DURATION            : female 6-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4
   per # born alive)
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   69,43,1983

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 175 mg/kg
SEX/DURATION            : female 7-13 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - cardiovascular
   (circulatory) system
REFERENCE :
   TJADAB Teratology, The Internation

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 100 ppm/6H
SEX/DURATION            : female 6-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - parturition
   Reproductive - Fertility - female fertility index (e.g. #

GHS Symbol
WGK Germany2
Hazard Codes 3 T
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
  • H370 Causes damage to organs 导致器官损伤
  • H302+H312+H332
  • H332 Harmful if inhaled 吸入有害
  • H312 Harmful in contact with skin 皮肤接触有害
  • H302 Harmful if swallowed 吞食有害
    Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
    Precautionary statements
    • P201 Obtain special instructions before use. 使用前获取专门指示。
    • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
    • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
    • P233 Keep container tightly closed. ?保持容器密闭。
    • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
    • P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
    • P241+P242+P243
    • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
    • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P302+P352+P312+P362+P364
    • P303+P361+P353
    • P304+P340+P311
    • P305+P351+P338
    • P305+P351+P338+P337+P313
    • P308+P311
    • P308+P313
    • P332+P313
    • P337+P313
    • P403+P233
    • P405 Store locked up. 上锁保管。
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Risk Statements
      • R10 Flammable 易燃
      • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
      • R48/22
      • R60 May impair fertility 可能降低生殖能力
      • R61 May cause harm to the unborn child 可能对未出生的婴儿导致伤害
        Safety Statements
        • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
        • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
          Packing GroupIII
          Storage condition 密封保存。
          Warnings 危化品目录(2015)
          Hazard Class3
          RTECSKL5775000
          UN Number 1188
          Signal word Danger
          Restrict 危险品
        • 测定铁;硫酸盐和二硫化碳的试剂,用作各种油脂类;木质素;硝基纤维素;乙酸纤维素;醇溶性染料和合成树脂的溶剂
        • {ALD} Merck:14,6038
        • Beilstein:1,467
        • {ALD} Merck:14,6038
        • 109-86-4 H63857 2-Methoxyethanol
2-甲氧基乙醇

          化学属性

          Mol. FormulaC3H8O2
          Density0.96
          Melting Point-85
          Flash Point41°C(lit.)
          Solubility与水混溶,可混溶于醇、酮、烃类。
          TSCAYes
          Autoignition Point548 °F
          Vapor Density2.62 (vs air)
          Vapor Pressure6.17 mmHg ( 20 °C)
          Stability对湿度敏感
          Boiling Point124
          Mol. Weight76
          Refractive index1.4010 to 1.4040

          *以上化合物性质及应用等信息仅供参考