Cyclen 轮环藤宁

规格: 98%
CAS: 294-90-6
产品编号: H65975
MDL: MFCD00066281
品牌: INFI
Chemical Name1,4,7,10-Tetraazacyclododecane
CAS Number294-90-6
Synonym Cyclen {LY} Cyclen {} {LY} Cyclen {} {} {LY} Cyclen {} {} {} {LY} Cyclen {} {} {} {} {LY} Cyclen {} {} {} {} {} {LY} Cyclen {} {} {} {} {} {} {LY} Cyclen {} {} {} {} {} {} {} {LY} Cyclen {} {} {} {} {} {} {} {} {LY} Cyclen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Cyclen {} {} {} {} {} {} {} {} {} {} {LY} Cyclen {} {} {} {} {} {} {} {} {} {} {} {LY} Cyclen {} {} {} {} {} {} {} {} {} {} {} {} {LY} Cyclen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Cyclen {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Cyclen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Cyclen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Cyclen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Cyclen {} {} {} {} {} {} {} {} {} {} {}
EC Number425-450-9
Beilstein Registry Number606114
MDL NumberMFCD00066281
PubChem Substance ID64963
Reaxys-RN606114
Alfabeta NameTETRAAZACYCLODODECANE 14710-,,,
Chemical Name Translation轮环藤宁
LabNetwork Molecule IDLN00185654
InChIInChI=1S/C8H20N4/c1-2-10-5-6-12-8-7-11-4-3-9-1/h9-12H,1-8H2
Canonical SMILESC1CNCCNCCNCCN1
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 388 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NATWAY Naturwissenschaften.  (Springer-Verlag, Heidelberger Platz 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.1-    1913-  Volume(issue)/page/year:
   70,201,1983

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 435 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 19,425,1984

Signal word Danger
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
    Risk Statements
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
    • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
      Precautionary statements
      • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P264+P265
      • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
      • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
      • P273 Avoid release to the environment. 避免释放到环境中。
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P301+P312
      • P301+P317
      • P301+P330+P331
      • P302+P350
      • P302+P352
      • P302+P361+P354
      • P303+P361+P353
      • P304+P340
      • P305+P351+P338
      • P305+P354+P338
      • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
      • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
      • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
      • P316
      • P317
      • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
      • P322 Specific measures (see …on this label). 具体治疗（见本标签上的）。
      • P330 Rinse mouth. 漱口
      • P332+P313
      • P337+P313
      • P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
      • P361+P364
      • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
      • P362+P364
      • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
      • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
      • P403+P233
      • P405 Store locked up. 上锁保管。
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
        Hazard statements
        • H302 Harmful if swallowed 吞食有害
        • H302+H312
        • H311 Toxic in contact with skin 皮肤接触中毒
        • H312 Harmful in contact with skin 皮肤接触有害
        • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
        • H315 Causes skin irritation 会刺激皮肤
        • H318 Causes serious eye damage 严重伤害眼睛
        • H319 Causes serious eye irritation 严重刺激眼睛
        • H331 Toxic if inhaled 吸入中毒
        • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
        • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
          Hazard Codes 8 Xi
          RTECSXA5253000
          Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
          Storage condition 2-8°C, protect from light, stored under nitrogen {LY} 2-8°C, protect from light, stored under nitrogen Refrigerator {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under ni
          Warnings IRRITANT
          UN Number 1759 3259
          Packing GroupIII
          Hazard Class8
        • Macrocyclic aza analogue of the crown ether 12-crown-4. Cyclen compounds are capable of selectively binding cations and are used as a ligand with chemicals used in MRI contrast (as well ass other imag
        • {ALD} Merck: 14,10413
        • {ALD} Merck: 14,10413
        • Beilstein:26(5)11,23
        • {TRC} Jeon, J.W. et al.: Bioorg. Med. Chem., 11, 2901 (2003);
          • 294-90-6 H65975 Cyclen 轮环藤宁

          化学属性

          Mol. FormulaC8H20N4
          Mol. Weight172.27
          Density0.874
          Melting Point108-113°C
          Boiling Point283.8°C at 760 mmHg

          *以上化合物性质及应用等信息仅供参考