(R)-(+)-2-Methyl-CBS-oxazaborolidine (R)-(+)-2-甲基-CBS-噁唑硼烷

规格: 1.0 M solution in THF, SpcSeal
CAS: 112022-83-0
产品编号: H66380
MDL: MFCD00078440
品牌: INFI
Chemical Name(R)-1-methyl-3,3-diphenylhexahydropyrrolo[1,2-c][1,3,2]oxazaborole
Synonym (R)-(+)-2-甲基-CBS-噁唑硼烷 溶液 (R)-2-METHYL-CBS-OXAZABOROLIDINE MONOHYDRATE ?-2-甲基-CBS-恶唑硼烷 (R)-2-METHYL-CBS-OXAZABOROLIDINE (R)-methyloxazaborolidine,(R)-mecbs,intoluene (R)-2-甲基-CBS-氧杂硼啶单水合物 ALPHA,ALPHA-DIPHENYL-D-PROLINOL METHYLBORONIC ACID CYCL-AMIDE-ESTER (R)-四氢-1-甲基-3,3-二苯基-1H,3H-吡咯并[1,2-c][1,3,2]噁唑硼烷 (R)-(+)-甲基-CBS-恶唑硼烷 (R)-四氢-1-甲基-3,3-二苯基-1H,3H-吡咯并[1,2-c][1,3,2]噁唑硼烷 (R)-1-甲基,3,3-二苯基-四氢-吡咯并(1,2-c)(1,3,2)噁唑硼烷 (R)-3-甲基-CBS-氧杂硼啶 (R)-2-甲基-CBS-恶唑硼烷 (R)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborlidine (R)-(+)-2-甲基-CBS-噁唑硼烷 (R)-1-甲基,3,3-二苯基-四氢-吡咯并(1,2-c)(1,3,2)噁唑硼烷 (R)-Methyl oxazaborolidine, in toluene, 1M solution (R)-TETRAHYDRO-1-METHYL-3,3-DIPHENYL-1H,3H-PYRROLO[1,2-C][1,3,2] OXAZABOROLE (R)-3,3-DIPHENYL-1-METHYLTETRAHYDRO-1H,3H-PYRROLO[1,2-C][1,3,2]OXAZABOROLE (R)-3-甲基-CBS-氧杂硼啶, 1M SOLN. IN TOLUENE (R)-2-甲基-CBS-噁唑硼烷 (R)-2-METHYL-CBS-OXAZABOROLIDINE, 1M IN& (R)-TETRAHYDRO-1-METHYL-3,3-DIPHENYL-1H,3H-PYRROLO[1,2-C][1,3,2]OXAZOBOROLE (R)-3,3-DIPHENYL-1-METHYLTETRAHYDRO-3H-PYRROLO-[1,2-C][1,3,2]OXAZABOROLE (R)-3-甲基-CBS-氧杂硼啶 (R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole (R)-3-甲基-CBS-氧杂硼啶 (R)-methyloxazaborolidine,(R)-mecbs,in ( R )-2-Methyl-CBS-Oxazaborolidine.H20 (R)-5,5-DIPHENYL-2-METHYL-3,4-PROPANO-1,3,2-OXAZABOROLIDINE (R)-ME (R)-Methyloxazaborolidine,1-1.5Mintoluene[(R)-MeCBS]
PubChem Substance ID9838490
Beilstein Registry Number9059874
EC Number250-023-7
Chemical Name Translation(R)-5,5-联苯-2-甲基-3,4-丙醇-1,3,2-恶唑硼烷
Reaxys-RN9059874
LabNetwork Molecule IDLN00009249
InChIInChI=1S/C18H20BNO/c1-19-20-14-8-13-17(20)18(21-19,15-9-4-2-5-10-15)16-11-6-3-7-12-16/h2-7,9-12,17H,8,13-14H2,1H3/t17-/m1/s1
MDL NumberMFCD00078440
CAS Number112022-83-0
GHS Symbol
WGK Germany3
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
    Packing GroupII
    UN Number UN 1294 3/PG 2
    Risk Statements
    • R11 Highly flammable 非常易燃
    • R19 May form explosive peroxides 可能生成易爆的过氧化物质
    • R36/37 Irritating to eyes and respiratory system 对眼睛和呼吸系统有刺激性
    • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
      Storage condition 0-10 Air & Moisture Sensitive 0-10°C 2-8°C 贮存温度:2-8°C
      Hazard statements
      • H319 Causes serious eye irritation 严重刺激眼睛
      • H335 May cause respiratory irritation 可能导致呼吸道刺激
      • H351 Suspected of causing cancer 怀疑致癌
      • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
      • H302 Harmful if swallowed 吞食有害
      • H315 Causes skin irritation 会刺激皮肤
      • H304 May be fatal if swallowed and enters airways 吞食和进入呼吸道可能致命
      • H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
      • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
      • H361d Suspected of damaging the unborn child 怀疑对未出生婴儿造成伤害
        Precautionary statements
        • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
        • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
        • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
        • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
        • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
        • P301+P310
        • P301+P312+P330
        • P305+P351+P338
        • P331 Do NOT induce vomiting.. 不要催吐。
        • P370+P378
        • P403+P235
          Signal word
          Hazard Codes
          Hazard Class3
        • CBS (Corey-Bakshi-Shibata) 噁唑硼烷催化剂已被用于前手性酮的非对称性还原。其他应用包括 α-羟基酸、α-氨基酸、C2 对称二茂铁二醇以及炔丙醇的对映选择性合成。
        • {ALF} Chiral auxiliary for the highly enantioselective reduction of prochiral ketones, see (S)-2-Methyl-CBS-oxazaborolidine monohydrate, L09219.
        • {ALF} Air-stable solid prepared by a modification of Corey's procedure, on which his literature results were based. For anhydrous reagent, see (R)-2-Methyl-CBS-oxazaborolidine, L14582.
        • {ALF} Anhydrous catalyst for CBS reduction reaction. For further information, see (S)-2-Methyl-CBS-oxazaborolidine monohydrate, L09219.
          • 112022-83-0 H66380 (R)-(+)-2-Methyl-CBS-oxazaborolidine (R)-(+)-2-甲基-CBS-噁唑硼烷

          化学属性

          Melting Point85-95
          TSCANo
          Refractive indexn20/D 1.4602
          Boiling Point111 °C
          Mol. FormulaC18H20BNO
          Mol. Weight277.17
          Density0.925
          Flash Point40°F (toluene)
          Appearance liq.
          Stabilitymoisture sensitive

          *以上化合物性质及应用等信息仅供参考