Diphenyl Chlorophosphate 氯磷酸二苯酯

规格: 98%
CAS: 2524-64-3
产品编号: H77116
MDL: MFCD00003030
品牌: INFI
Chemical NameDiphenyl Phosphorochloridate
MDL NumberMFCD00003030
CAS Number2524-64-3
EC Number219-759-6
Beilstein Registry Number654130
Synonym Diphenyl chlorophosphate {LY} Diphenyl chlorophosphate {} {LY} Diphenyl chlorophosphate {} {} {LY} Diphenyl chlorophosphate {} {} {} {LY} Diphenyl chlorophosphate {} {} {} {} {LY} Diphenyl chlorophosphate {} {} {} {} {} {LY} Diphenyl chlorophosphate {} {} {} {} {} {} {LY} Diphenyl chlorophosphate {} {} {} {} {} {} {} {LY} Diphenyl chlorophosphate {} {} {} {} {} {} {} {} {LY} Diphenyl chlorophosphate {} {} {} {} {} {} {} {} {} {LY} Diphenyl chlorophosphate {} {} {} {} {} {} {} {} {} {} {LY} Diphenyl chlorophosphate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Diphenyl chlorophosphate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Diphenyl chlorophosphate {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Diphenyl chlorophosphate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Diphenyl chlorophosphate {} {} {} {} {} {} {} {} {} {} {
PubChem Substance ID87567629
Chemical Name Translation氯磷酸二苯酯
Reaxys-RN654130
LabNetwork Molecule IDLN00191619
InChIInChI=1S/C12H10ClO3P/c13-17(14,15-11-7-3-1-4-8-11)16-12-9-5-2-6-10-12/h1-10H
Canonical SMILESO=P(Cl)(OC1=CC=CC=C1)OC2=CC=CC=C2
GHS Symbol
Signal word Danger
WGK Germany2
Safety Statements
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾；
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S7 Keep container tightly closed 保存在严格密闭容器中；
    Risk Statements
    • R34 Causes burns 会导致灼伤
    • R37 Irritating to respiratory system 刺激呼吸道
      Precautionary statements
      • P234 Keep only in original container. 只保留在原来的容器中。
      • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P301+P330+P331
      • P301+P330+P331+P310
      • P303+P361+P353+P310+P363
      • P304+P340
      • P304+P340+P310
      • P305+P351+P338
      • P305+P351+P338+P310
      • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
      • P390 Absorb spillage to prevent material damage. 吸收溢出物，防止重大损害。
      • P405 Store locked up. 上锁保管。
      • P406 Store in corrosive resistant/… container with a resistant inner liner. 存放在耐腐蚀/具有耐性的内衬容器。
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
        Hazard statements
        • H290 May be corrosive to metals 可能腐蚀金属。
        • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
          Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
          Packing GroupII
          UN Number 3265 UN 3265 8/PG 2 UN3265
          Storage condition 2-8°C {LY} 2-8°C Moisture Sensitive {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
          Hazard Codes 8 C
          Hazard Class8
        • 磷酸化试剂，用于被保护的丝氨酸和吡喃糖。
        • {ALF} Diphenylphosphate has also been exploited as a good leaving group in the high yield conversion (equivalent to dehydration) of secondary alcohols to olefins by thermal elimination: Synthesis, 1300 (1995). For further information, see Triphenyl­ phosphate, L08130. Other conversions, generally in the presence of a base such as triethylamine, in which the equivalent of a dehydration step occurs are:
        • {ALF}
        • {ALF} Hydrogenolysis of the phenyl groups yields the monophosphate ester of the alcohol. Glycosyl monophosphates have been prepared in this way. Alternatively, treatment of the glycosyl diphenyl phosphate with sodium azide in DMF provides a high yield route to glycosyl azides: Carbohydr. Res., 223, 169 (1992).
        • {ALF} Aldoximes to nitriles at room temperature: J. Org. Chem., 34, 2805 (1969). Peptide coupling (see Appendix 6), via the mixed carboxyl phosphate anhydride: Chem. Ber., 94, 2644 (1961). Carboxylic acids to anhydrides: Synthesis, 219 (1981). ω-Hydroxy acids to macrolides, promoted by DMAP: J. Org. Chem., 47, 1612 (1982).
        • {ALF} Diphenylphosphate esters, formed with or without catalysis by DMAP, undergo a variety of transformations:
        • {ALF} See also Diphenyl­phosphonic azide, A12124.
        • {ALF} Lithium enolates give enol diphenylphosphates in which the phosphate moiety acts as a leaving group; e.g., ketone enol phosphates have been converted to the corresponding alkene by reaction with organocuprates: Tetrahedron Lett., 4405 (1976). With amides, internal displacement occurs; subsequent reaction with NaN3 gives azirines: Helv. Chim. Acta, 76, 2830 (1993):
          • 2524-64-3 H77116 Diphenyl Chlorophosphate 氯磷酸二苯酯

          化学属性

          Mol. FormulaC12H10ClO3P
          Mol. Weight268.63
          Density1.296
          Refractive index1.5480 to 1.5520
          Boiling Point363.5°C at 760 mmHg
          Vapor Pressure10 mmHg ( 190 °C)
          Flash Point>113°C
          TSCAYes
          SolubilityMAY DECOMPOSE
          Appearance 无色透明液体，沸点:314-316℃
          Stability对湿度敏感

          *以上化合物性质及应用等信息仅供参考