Chemical Name | Ethyl Bromodifluoroacetate |
CAS Number | 667-27-6 |
Alfabeta Name | ETHYLBROMODIFLUOROACETATE |
MDL Number | MFCD00042069 |
PubChem Substance ID | 87564380 |
EC Number | 211-567-0 |
Beilstein Registry Number | 1906095 |
Reaxys-RN | 1906095 |
Synonym |
difluorobromo ethyl acetate
Acetic acid, bromodifluoro-, ethyl ester
Acetic acid, 2-bromo-2,2-difluoro-, ethyl ester
Ethyl bromodifluoroacetate 98%
溴二氟乙酸乙酯
1-溴一二氟乙酸乙酯;溴二氟乙酸乙酯
二氟溴乙酸乙酯
BROMODIFLUOROACETIC ACID ETHYL ESTER
ETHYL BROMODIFLUOROACETATE
Ethyl 2,2-difluoro-2-bromoacetate
Difluorobromoacetic acid ethyl ester |
Chemical Name Translation | 溴二氟乙酸乙酯 |
InChIKey | IRSJDVYTJUCXRV-UHFFFAOYSA-N |
LabNetwork Molecule ID | LN00116599 |
InChI | InChI=1S/C4H5BrF2O2/c1-2-9-3(8)4(5,6)7/h2H2,1H3 |
Warnings |
IRRITANT, FLAMMABLE |
GHS Symbol
WGK Germany | 3 |
Hazard statements | |
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
- H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
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Personal Protective Equipment |
Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
Hazard Codes |
C |
Precautionary statements | |
- P303+P361+P353+P310+P363
- P304+P340+P310
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- P305+P351+
- P301+P330+P331
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
- P304+P340
- P405 Store locked up. 上锁保管。
- P233 Keep container tightly closed. ?保持容器密闭。
- P241+P242+P243
- P301+P330+P331+P310
- P403+P235
- P305+P351+P338+P310
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
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Signal word |
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UN Number |
UN2924
2924 |
Risk Statements | |
- R10 Flammable 易燃
- R34 Causes burns 会导致灼伤
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Safety Statements | |
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
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Packing Group | II |
Hazard Class | 3/8 |
Storage condition |
Flammables area |
Usually used in the preparation of substituted ethyl 2′-pyridyldifluoroacetates,4-alkoxymethyl- and 4-aryloxymethyl-3,3-difluoropiperidines,α,α-difluoro-β-lactams,mono- and difluoromethylated phenanthridine derivatives.
{ALF} Valuable building block for the introduction of the CF2 group by Reformatsky reaction with aldehydes. A further development of this chemistry involves the generation of an ɑɑ-difluoro-ß-lactone, followed by thermal decarboxylation as a high-yield route to 1,1-difluoroalkenes: J. Org. Chem., 60, 5378 (1995):
{ALF}