GHS Symbol
| WGK Germany | 1 |
|---|
| Hazard Codes |
T |
| Hazard statements | |
|---|
- H351 Suspected of causing cancer 怀疑致癌
- H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
- H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
- H320 Causes eye irritation 刺激眼睛
- H316 Causes mild skin irritation 会轻微的刺激皮肤
- H340 May cause genetic defects 可能导致遗传性缺陷
- H331 Toxic if inhaled 吸入中毒
- H318 Causes serious eye damage 严重伤害眼睛
|
| Personal Protective Equipment |
Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
| RTECS | LQ0525000 |
|---|
| Precautionary statements | |
|---|
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- P305+P351+P338+P337+P313
- P308+P313
- P332+P313
- P501 Dispose of contents/container to..… 处理内容物/容器.....
|
| Signal word |
Danger |
| Safety Statements | |
|---|
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- S53 Avoid exposure - obtain special instructions before use 避免接触，使用前获得特别指示说明；
|
| Risk Statements | |
|---|
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
- R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
- R61 May cause harm to the unborn child 可能对未出生的婴儿导致伤害
|
| Storage condition |
密封保存
密封保存。测序级2-8°C保存
充氩保存
Hygroscopic
2-8°C |
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 5700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
26,596,1973
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 1250 mg/kg
TOXIC EFFECTS :
Autonomic Nervous System - other (direct) parasympathomimetic
Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv.
Toxicology of New Industrial Chemical Substances. For English translation,
see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961-
Volume(issue)/page/year: 9,163,1967
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APEPA2 Naunyn-Schmiedebergs Archiv fuer Pharmakologie und Experimentelle
Pathologie. (Berlin, Ger.) V.254-263, 1966-69. For publisher information,
see NSAPCC. Volume(issue)/page/year: 257,296,1967
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >13500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PJPPAA Polish Journal of Pharmacology and Pharmacy.
TYPE OF TEST : Cytogenetic analysis
TEST SYSTEM : Non-mammalian species Cells - not otherwise specified
DOSE/DURATION : 500 mmol/L
REFERENCE :
CAANAT Comptes Rendus de l'Association des Anatomistes. (Nancy, France)
V.1-56, 1899-1972. For publisher information, see ANOBAU.
Volume(issue)/page/year: 56,712,1972
TYPE OF TEST : Mutation test systems - not otherwise specified
TEST SYSTEM : Non-mammalian species Cells - not otherwise specified
DOSE/DURATION : 500 mmol/L
REFERENCE :
CAANAT Comptes Rendus de l'Association des Anatomistes. (Nancy, France)
V.1-56, 1899-1972. For publisher information, see ANOBAU.
Volume(issue)/page/year: 56,712,1972
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 7980 mg/kg
SEX/DURATION : female 7-12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - craniofacial
(including nose and tongue)
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
85DJA5 "Malformations Congenitales des Mammiferes," Tuchmann-Duplessis, H.,
Paris, Masson et Cie, 1971 Volume(issue)/page/year: -,95,1971
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE : 910 mg/kg
SEX/DURATION : female 6-18 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 30,1557,1980
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 2 gm/kg
SEX/DURATION : female 7 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
REFERENCE :
85DJA5 "Malformations Congenitales des Mammiferes," Tuchmann-Duplessis, H.,
Paris, Masson et Cie, 1971 Vol
