| Chemical Name | Titanium(IV) Chloride |
|---|
| Synonym |
(t-4)-titaniumchloride(ticl4
TITANIUM ATOMIC SPECTROSCOPY STANDARD (TICL4)
TITANIUM CHLORIDE
TITANIUM(IV) CHLORIDE
TITANIUM(IV) TETRACHLORIDE
Tetrachlorotitanium
Tetrachlorotitanium; Titanic chloride
Tetrachlorure de titane
Titane
Titanic chloride
Titanium chloride (TiCl4) (t-4)-
Titanium tetrachl
Titanium tetrachloride
Titanium tetrachloride, Titanic chloride
Titanium tetrachloride; Titanic chloride
Titantetrachlorid
tetrachloruredetitane
titane(tetrachlorurede)(french)
四氯化钛
四氯化钛(IV)
四氯化钛(IV) 溶液 四氯化钛
四氯化钛(IV), 99.0% MIN, TYPICALLY 99.6%
四氯化钛(禁运)
四氯化钛, 99.99% (METALS BASIS)
氯化钛
氯化钛;TTC |
| EC Number | 231-441-9 |
|---|
| Merck Number | 9478 |
|---|
| PubChem Substance ID | 87558543 |
|---|
| Beilstein Registry Number | 2384789 |
|---|
| Chemical Name Translation | 四氯化钛 |
|---|
| InChIKey | XJDNKRIXUMDJCW-UHFFFAOYSA-J |
|---|
| Wiswesser Line Notation | TI G4 |
|---|
| LabNetwork Molecule ID | LN00220931 |
|---|
| MDL Number | MFCD00011267 |
|---|
| CAS Number | 7550-45-0 |
|---|
GHS Symbol
| WGK Germany | 2 |
|---|
| Hazard Codes |
6.1
C |
| Hazard statements | |
|---|
- H301 Toxic if swallowed 吞食有毒
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
- H335 May cause respiratory irritation 可能导致呼吸道刺激
|
| Personal Protective Equipment |
Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
| RTECS | XR1925000 |
|---|
| Precautionary statements | |
|---|
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P310
- P303+P361+P353
- P305+P351+P338
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
|
| Signal word |
Danger |
| UN Number |
1838
3289
UN2924 |
| Risk Statements | |
|---|
- R14 Reacts violently with water 遇水会猛烈反应
- R34 Causes burns 会导致灼伤
- R37 Irritating to respiratory system 刺激呼吸道
- R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
- R67 Vapours may cause drowsiness and dizziness 蒸汽可能导致嗜睡和昏厥
|
| Safety Statements | |
|---|
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
|
| Storage condition |
Moisture Sensitive
储存温度2-8℃,充氩保存
Flammables area
密封干燥保存。
0-10°C
0-10 |
| Packing Group | II |
|---|
| Hazard Class | 6.1/8 |
|---|
| Warnings |
危化品目录(2015) |
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 100 mg/m3/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
GKNT, 1982 Volume(issue)/page/year: -,111,1982
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 400 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
GKNT, 1982 Volume(issue)/page/year: -,111,1982
| Restrict |
危险品 |
活化四氢吡咯以提高通过修正的波沃反应转化成相应的 α,α-二甲胺的转化率。促进 (S)-2-苄氧-3-戊酮在 THF 或 DME 中的高选择性羟醛缩合反应。
{ALF} In combination with NaI, for reduction of amine oxides and nitrones to amines: Chem. Ber., 123, 647 (1990); and sulfoxides to sulfides: Synthesis, 155 (1991). With Mg, for deoxygenation of aromatic N-oxides: Synthesis, 732 (1987). With LAH for the otherwise difficult reduction of sulfones to sulfides: J. Chem. Soc., Chem. Commun., 761 (1994). Reviews of low-valent titanium reagents in organic synthesis: Synthesis, 883 (1989); J. Organomet. Chem., 405, 1 (1991); J. Prakt. Chem./ Chem. Ztg., 337, 250 (1995).
{ALFA} Moderately strong Lewis acid with extremely wide application. Review of use in organic synthesis: Angew. Chem. Int. Ed., 16, 817 (1977). Brief feature: Synlett, 364 (2002).
{ALFA} Conversion of ketones to N-alkylimines: Org. Synth. Coll., 6, 818 (1988); Acta Chem. Scand., 46, 1211 (1992). Aldol condensation of aryl ketones with aryl aldehydes: Tetrahedron Lett., 28, 4135 (1987). Crossed aldol condensation of silyl enol ethers with carbonyl compounds: J. Am. Chem. Soc., 96, 7503 (1974); Org. Synth. Coll., 8, 323 (1993). ɑ-Tert-alkylation of ketones by reaction of the silyl enol ether with a tertiary halide: Org. Synth. Coll., 7, 424 (1990); review: Angew. Chem. Int. Ed., 21, 96 (1982); see also Zinc chloride, A16281. Michael addition of silyl enol ethers to ɑß-enones: Org. Synth. Coll., 8, 210 (1993). For conjugate allylation of ɑß-enones, see Allyl­trimethyl­silane, A14662. Regiospecific [3+2] annulation of enones with silylated allenes: J. Am. Chem. Soc., 103, 1604 (1981); Tetrahedron, 39, 935 (1983); Org. Synth. Coll., 8, 347 (1993):
{ALD} Merck: 14,9478
{ALFA} Examples of reactions mediated by TiCl4:
{ALFA} For use in a diastereoselective Mannich reaction, see: Helv. Chim. Acta, 67, 1593 (1984). Also used in combination with reducing agents for the generation of low-valent Ti species, which effect the reduction of various functional groups:
{ALFA} In combination with NaI, for reduction o
