2-(Trimethylsilyl)ethanol 2-(三甲硅基)乙醇

规格:
CAS: 2916-68-9
产品编号: HXYJ0000000305
MDL: MFCD00002825
品牌: Bellen
Chemical Name(2-Hydroxyethyl)Trimethylsilane
CAS Number2916-68-9
Alfabeta NameTRIMETHYLSILYLETHANOL 2-
MDL NumberMFCD00002825
Synonym (2-Hydroxyethyl)trimethylsilane {LY} (2-Hydroxyethyl)trimethylsilane {} {LY} (2-Hydroxyethyl)trimethylsilane {} {} {LY} (2-Hydroxyethyl)trimethylsilane {} {} {} {LY} (2-Hydroxyethyl)trimethylsilane {} {} {} {} {LY} (2-Hydroxyethyl)trimethylsilane {} {} {} {} {} { {} {} {} {} {} {LY} (2-Hydroxyethyl)trimethylsilane {} {} {} {} {} {} {LY} (2-Hydroxyethyl)trimethylsilane {} {} {} {} {} {} {} {LY} (2-Hydroxyethyl)trimethylsilane {} {} {} {} {} {} {} {} {LY} (2-Hydroxyethyl)trimethylsilane {} {} {} {} {} {} {} {} {} {LY} (2-Hydroxyethyl)trimethylsilane {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} (2-Hydroxyethyl)trimethylsilane {} {} {} {} {} {} {} {} {} {} {} {LY} (2-Hydroxyethyl)trimethylsilane {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} (2-Hydroxyethyl)trimethylsilane {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} (2-Hydroxyethyl)trimethylsilane
EC Number220-844-5
Beilstein Registry Number1732034
PubChem Substance ID87577204
Reaxys-RN1732034
Chemical Name Translation2-三甲基硅基乙醇
InChIKeyZNGINKJHQQQORD-UHFFFAOYSA-N
Wiswesser Line NotationQ2-SI-1&1&1
LabNetwork Molecule IDLN00009690
InChIInChI=1S/C5H14OSi/c1-7(2,3)5-4-6/h6H,4-5H2,1-3H3
Canonical SMILESC[Si](CCO)(C)C
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1122 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DANKAS Doklady Akademii Nauk SSSR.  Proceedings of the Academy of Sciences
   of the USSR.  For English translation, see DBIOAM and DKBSAS.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-    1933-
   Volume(issue)/page/year: 229,1011,1976

Warnings FLAMMABLE
Signal word Warning
WGK Germany3
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
    Risk Statements
    • R10 Flammable 易燃
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      Precautionary statements
      • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
      • P233 Keep container tightly closed. ?保持容器密闭。
      • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
      • P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
      • P241+P242+P243
      • P242 Use only non-sparking tools. 只能使用无火花工具。
      • P243 Take precautionary measures against static discharge. 采取预防措施，防止静电放电。
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P302+P352
      • P302+P352+P332+P313+P362+P364
      • P303+P361+P353
      • P305+P351+P338
      • P305+P351+P338+P337+P313
      • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
      • P332+P313
      • P337+P313
      • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
      • P370+P378
      • P403+P235
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
        RTECSKM5480000
        Packing GroupIII
        UN Number 1987 1993
        Hazard statements
        • H226 Flammable liquid and vapour 易燃液体和蒸气
        • H315 Causes skin irritation 会刺激皮肤
        • H319 Causes serious eye irritation 严重刺激眼睛
          Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
          Hazard Codes 3
          Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {}
          Hazard Class3
        • 经由相关异氰酸酯的醇解，合成Teoc-protected 胺。也是羧基和磷酸根基团的保护试剂。
        • {ALD} Beilstein:4(4)3951
        • {uni_hamburg} Short: III/35F
        • {ALF} Carboxyl groups can be protected as 2-(trimethylsilyl)ethyl (TMSE) esters by carbodiimide coupling: Helv. Chim. Acta, 60, 2711 (1977); J. Org. Chem., 62, 93 (1997), from the acid chloride in pyridine: Helv. Chim. Acta, 60, 3039 (1977), or refluxing the acid in THF in the presence of TMS chloride: J. Am. Chem. Soc., 106, 3030 (1984). The TMSE protecting group is useful in peptide synthesis. Cleavage is readily effected with TBAF in DMF or DMSO: Helv. Chim. Acta, 60, 2711 (1977); Bioorg. Med. Chem. Lett., 3, 437 (1993).
        • {uni_hamburg} Short: EINECS
          • 2916-68-9 HXYJ0000000305 2-(Trimethylsilyl)ethanol 2-(三甲硅基)乙醇

          化学属性

          Mol. FormulaC5H14OSi
          Mol. Weight118.25
          Boiling Point145°C at 760 mmHg
          Density0.825
          Refractive index1.4230 to 1.4250
          Flash Point56°C
          TSCANo
          Solubility可溶

          *以上化合物性质及应用等信息仅供参考