Chemical Name | tert-Butyllithium |
Synonym |
叔丁基锂, NOMINALLY 1.5M IN N-PENTANE
叔丁基锂1.6M戊烷溶液
ButyllithiuminpentaneMslightlycloudyliq
TERT-BUTYLLITHIUM
2-甲基-2-丙基锂
LITHIUM TERT-BUTYL
tert-butyl-lithium
3-丁基锂
tert-Butyllithium
叔丁基锂
叔丁基锂 溶液
tert.-Butyl-lithium
(1,1-dimethylethyl)-lithiu
tert.-Butyllithium
T-BUTYLLITHIUM
Lithium,(1,1-dimethylethyl)-
tert-Butyl lithium
tert-Butyllithium,nominally1.5Minn-pentane
t-Butyllithium 16% in pentane (1-2M)
TERT-BUTYLLITHIUM, 1.7M SOLUTION IN PENT
Lithium-2-methyl-2-propanide, t-BuLi
tert-Butyllithium solution
TERT-BUTYLLITHIUM SOLUTION IN HEPTANE
TERT-BUTYLLITHIUM SOLUTION, ~1.5 M IN PE NTANE
叔丁基锂 NOMINALLY 1.5M IN N-PENTANE, PACKAGED UNDER ARGON
t-butyl-lithium
T-BULI
Lithium, (1,1-dimethylethyl)-
t-Butyllithium
packagedunderArgoninresealableChemSealbottles
TERT-BUTYLLITHIUM 1.7 M IN PENTANE
Lithium, tert-butyl-
Lithium-tert-butyl
(1,1-Dimethylethyl)lithium
LITHIUM-2-METHYL-2-PROPANIDE
第三丁基鋰 (須冷藏)
1,1-Dimethyl-ethane-lithium |
CAS Number | 594-19-4 |
EC Number | 209-831-5 |
Beilstein Registry Number | 4(3)2035 |
MDL Number | MFCD00008795 |
PubChem Substance ID | 638178 |
Reaxys-RN | 3587204 |
Chemical Name Translation | 叔丁基锂 |
InChIKey | BKDLGMUIXWPYGD-UHFFFAOYSA-N |
LabNetwork Molecule ID | LN00224230 |
InChI | InChI=1S/C4H9.Li/c1-4(2)3;/h1-3H3;/q-1;+1 |
Signal word |
|
GHS Symbol
WGK Germany | 1 |
Safety Statements | |
- S9 Keep container in a well-ventilated place 保持容器在通风良好的场所;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
- S33 Take precautionary measures against static discharges 对静电采取预防措施;
- S43 In case of fire use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add -?Never use water) 着火时使用(指明具体的消防器材种类,如果用水增加危险,注明“禁止用水”
- S62 If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label where possible 吞食后不要催吐:立即求医并出示该容器或标签;
- S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
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Risk Statements | |
- R11 Highly flammable 非常易燃
- R17 Spontaneously flammable in air 在空气中能够自燃
- R14/15 Reacts violently with water, liberating extremely flammable gases 遇水剧烈反应,释放出高度可燃气体
- R34 Causes burns 会导致灼伤
- R65 Harmful: may cause lung damage if swallowed 若吞咽可能伤害肺部器官
- R66 Repeated exposure may cause skin dryness or cracking 反复接触可能导致皮肤干燥或皴裂
- R67 Vapours may cause drowsiness and dizziness 蒸汽可能导致嗜睡和昏厥
- R51/53
- R15 Contact with water liberates extremely flammable gases 遇水会释放出极端易燃的气体
- R38 Irritating to skin 刺激皮肤
- R50/53
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Precautionary statements | |
- P222 Do not allow contact with air. 不要与空气接触。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P223 Keep away from any possible contact with water, because of violent reaction and possible flash fire. 远离任何与水接触的可能,因为会剧烈反应可能产生闪火。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
- P370+P378
- P422 Store contents under… 存储目录在…之下。
- P231+P232
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P403+P233
- P305+P351+P338+P310
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
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Hazard statements | |
- H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
- H304 May be fatal if swallowed and enters airways 吞食和进入呼吸道可能致命
- H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
- H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
- H260 In contact with water releases flammable gases which may ignite spontaneously 与水接触时释放可燃气体,可自燃。
- H250 Catches fire spontaneously if exposed to air 暴露于空气自发着火
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Personal Protective Equipment |
Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
Packing Group | I |
UN Number |
|
Storage condition |
Air & Moisture Sensitive
0-10°C
0-10
2-8°C储存,隔绝空气和水份
储存温度2-8℃; 充氩保存
2-8°C |
Hazard Codes |
F,C,N |
Hazard Class | 4.2/4.3 |
Warnings |
危化品目录(2015) |
Restrict |
危险品 |
⑴. 叔丁基锂溶液暴露于空气或湿气时易起火。
⑵.主要用于羰基化合物的烷基化、脱溴剂及有机合成。
⑶. 用于重要的锂试剂。通过卤素一金属交换反应而可用于制备其它有机铿化合物,如芳基铿、三烷基氢化硼锉、乙烯基锉、a一铿烷基苯硫醚、β一铿代烯胺等。在温和条件下还原拨基成怒基也是聚合反应的引发剂。
⑷.叔丁基锂相比正丁基锂和异丁基锂而言,具有更强的碱性和金属化活性以及更弱的亲核性,因此能够用于质子酸性更弱的烃类底物的脱质子锂化反应。通常,简单烷烃对于叔丁基锂仍然能保持惰性,但是对于含杂原子的溶剂如THF则会与叔
有机催化反应
{uni_hamburg} Short: III/35C4
{uni_hamburg} Short: EINECS
{uni_hamburg} Short: III/5a
{ALD} Beilstein:4(3)2035