4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo{8.8.8}-hexacosane 4,7,13,16,21,24-六氧-1,10-二氮双环[8.8.8]二十六烷

规格:
CAS: 23978-09-8
产品编号: HXYJ0000010943
MDL: MFCD00005111
品牌: Bellen
Chemical Name4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane
MDL NumberMFCD00005111
PubChem Substance ID87571288
Beilstein Registry Number620282
EC Number245-962-4
CAS Number23978-09-8
Synonym 13,16,21,24-Hexaoxa-1,10-diazabicyclo-(8,8,8)-hexacosane 4,7,13,16,21,24-六氧-1,10-二氮双环[8.8.8]二十六烷 Cryptand 222 Kryptofix® 222 Kryptofix 222 Kryptofix® 222 Ligand 222
Chemical Name Translation4,7,13,16,21,24-六氧-1,10-二氮双环[8.8.8]二十六烷
Reaxys-RN620282
Wiswesser Line NotationT-18--18- A B C D E F G H CO FO IN LO OO RN UO A&OTJ
LabNetwork Molecule IDLN00188901
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 35 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   41,113,1977

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 110 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   41,113,1977

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 32 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   41,113,1977

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 153 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   41,113,1977

WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
    Hazard statements
    • H315 Causes skin irritation 会刺激皮肤
    • H319 Causes serious eye irritation 严重刺激眼睛
    • H335 May cause respiratory irritation 可能导致呼吸道刺激
      RTECSMP4750000
      Signal word Warning
      Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
      Safety Statements
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
      • S36 Wear suitable protective clothing 穿戴适当的防护服；
      • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
        Risk Statements
        • R22 Harmful if swallowed 吞咽有害
        • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
          Hazard Codes Xn Xi Xi,Xn
          23978-09-8 HXYJ0000010943 4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo{8.8.8}-hexacosane 4,7,13,16,21,24-六氧-1,10-二氮双环[8.8.8]二十六烷

          化学属性

          Mol. FormulaC18H36N2O6
          Mol. Weight376
          Melting Point68-72
          Density1.422
          Solubility可溶

          *以上化合物性质及应用等信息仅供参考