研峰科技 Infinity Scientific

Dicyclohexano-18-crown-6 二环己烷并-18-冠醚-6

规格:

CAS: 16069-36-6

产品编号: HXYJ0000015189

MDL: MFCD00005099

品牌: Bellen

Chemical Name	Dicyclohexano-18-Crown-6
CAS Number	16069-36-6
Alfabeta Name	ICOSAHYDRODIBENZOHEXAOXACYCLOOCTADECINE BK147101316[[]]-,,,,,,
MDL Number	MFCD00005099
Synonym	Perhydrodibenzo-18-crown-6; 2,3,11,12-Dicyclohexano-1,4,7,10,13,16- hexaoxacyclooctadecane D2-06 二环己烷并-18-冠醚-6 全氢-二苯并-18-冠-6 2,5,8,15,18,21-Hexaoxatricyclo(20.4.0.0(sup 9,14))hexacosane 2,3,11,12-双环己基-1,4,7,10,13,16-六氧环十八烷 Dicyclohexano-18-crown-6 二环己基并-18-冠醚-6 2,5,8,15,18,21-六氧杂三环[20.4.0.09.14]二十六烷 Dicyclohexyl-18-crown-6 2,3,11,12-双环己基-1,4,7,10,13,16-六氧环十八烷 2,5,8,15,18,21-六氧杂三环[20.4.0.09.14]二十六烷二环己基并-18-冠醚-6 全氢-二苯并-18-冠-6
PubChem Substance ID	87568145
EC Number	240-216-4
Beilstein Registry Number	1130529
Merck Number	14,2602
Reaxys-RN	1130529
Chemical Name Translation	二环己烷并-18-冠醚-6

GHS Symbol

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 130 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0571202

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 192 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle contraction or spasticity
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 52(11),72,1987

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 130 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals",
   11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year:

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 53 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   DCTODJ Drug and Chemical Toxicology.  (Marcel Dekker, 270 Madison Ave., New
   York, NY 10016) V.1-    1977/78-  Volume(issue)/page/year: 8,451,1

TYPE OF TEST

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 105 mg/kg
SEX/DURATION            : female 1-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - other effects to embryo
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 52(11),72,1987

Warnings	IRRITANT
WGK Germany	1
Hazard statements
H301 Toxic if swallowed 吞食有毒 H315 Causes skin irritation 会刺激皮肤 H331 Toxic if inhaled 吸入中毒 H311 Toxic in contact with skin 皮肤接触中毒 H335 May cause respiratory irritation 可能导致呼吸道刺激 H319 Causes serious eye irritation 严重刺激眼睛
Personal Protective Equipment	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
RTECS	HP5385000
Precautionary statements
P301+P310 P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。 P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。 P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。 P305+P351+P338 P301+P310+P330 P501 Dispose of contents/container to..… 处理内容物/容器..... P332+P313 P405 Store locked up. 上锁保管。 P305+P351+P338+P337+P313 P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。 P337+P313 P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。 P304+P340+P312 P302+P352+P312 P403+P233
Signal word	Danger
Safety Statements
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护； S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗； S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见； S38 In case of insufficient ventilation wear suitable respiratory equipment 通风不良时，佩带适当的呼吸器； S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）； S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Packing Group	III
UN Number	2811 UN2811
Risk Statements
R24/25 Toxic in contact with skin and if swallowed 皮肤接触及吞食都有毒 R36 Irritating to eyes 刺激眼睛 R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性 R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒 R25 Toxic if swallowed 吞咽有毒
Storage condition	Hygroscopic
Hazard Codes	T
Hazard Class	6.1

{ALF} Crown ether (see Appendix 2). Increases the rate of acetolysis of benzyl chloride in acetonitrile by a factor of >;400: Synthesis, 117 (1981).

{ALF} In combination with potassium permanganate, effects the stereoselective cis-hydroxylation of a double bond from the less-hindered side: Chem. Lett., 173 (1983).

16069-36-6 HXYJ0000015189 Dicyclohexano-18-crown-6 二环己烷并-18-冠醚-6

化学属性

Mol. Formula	C20H36O6
Mol. Weight	373
Melting Point	47-50 °C
Flash Point	>110°(230°F)
TSCA	Yes
Boiling Point	344°C(lit.)
Solubility	略溶于水

*以上化合物性质及应用等信息仅供参考