Methyl isobutyl ketone, reagent grade, ACS 甲基异丁基甲酮

规格: reagent grade, ACS
CAS: 108-10-1
产品编号: ME04932500
MDL: MFCD00008938
品牌: Scharlab
Chemical Name4-Methyl-2-pentanone
Synonym 4-Methylpentan-2-one {LY} 4-Methylpentan-2-one Isobutylmethylketon Ketone, isobutyl methyl MIBK Methyl 2-methylpropyl ketone Methyl isobutyl ketone {} {LY} 4-Methylpentan-2-one {} {} {LY} 4-Methylpentan-2-one {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {} {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Methylpentan-2-one {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Methylpen
CAS Number108-10-1
PubChem Substance ID7909
EC Number203-550-1
Beilstein Registry Number605399
MDL NumberMFCD00008938
Reaxys-RN605399
Merck Number5207
Chemical Name Translation甲基异丁基甲酮
Wiswesser Line Notation1Y1&1V1
LabNetwork Molecule IDLN00001729
InChIInChI=1S/C6H12O/c1-5(2)4-6(3)7/h5H,4H2,1-3H3
Canonical SMILESCC(CC(C)C)=O
GHS Symbol
TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4000 ppm/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine.
   (Chicago, IL)  V.2-10, 1950-54. For publisher information

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 1396 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 51(5),61,1986

TYPE OF TEST            : LC50 - Lethal conc

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton,
   G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82.
   Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985.
   Volume(issue)/page/year: 2C,4748,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >20 mL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   UCDS** Union Carbide Data Sheet.  (Union Carbide Corp., 39 Old Ridgebury
   Rd., Danbury, CT 06817)  Volume(issue)/page/year: 4/25/1958

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 3000 ppm/6H
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - Central Nervous System
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
   Reproductive - Specific Developmental Abnormalities - cardiovascular
   (circulatory) system
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   8,310,1987

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 300 ppm/6H
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   8,310,1987

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 3000 ppm/6H
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   8,310,1987

WGK Germany1
Hazard Codes 3 F,Xn,T
Hazard statements
  • H332 Harmful if inhaled 吸入有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H319 Causes serious eye irritation 严重刺激眼睛
    Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
    RTECSSA9275000
    Precautionary statements
    • P201 Obtain special instructions before use. 使用前获取专门指示。
    • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
    • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
    • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P303+P361+P353
    • P304+P340
    • P305+P351+P338
    • P308+P313
    • P337+P313
    • P370+P378
    • P403+P233
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Danger
      UN Number 1245 UN1245
      Risk Statements
      • R11 Highly flammable 非常易燃
      • R20 Harmful by inhalation 吸入有害
      • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒
      • R36/37 Irritating to eyes and respiratory system 对眼睛和呼吸系统有刺激性
      • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      • R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性：吸入，皮肤接触和吞食都会产生十分严重的不可逆危险
      • R66 Repeated exposure may cause skin dryness or cracking 反复接触可能导致皮肤干燥或皴裂
        Safety Statements
        • S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
        • S29 Do not empty into drains 不要排入下水道；
        • S9 Keep container in a well-ventilated place 保持容器在通风良好的场所；
          Packing GroupII
          Storage condition 2-8°C {LY} 2-8°C 4°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C
          Hazard Class3
          Warnings 危化品目录(2015)
          Restrict 危险品
        • 是优良的中沸点溶剂。用作选矿剂；油品脱蜡用溶剂；彩色影片的成色剂，也用作四环素和除虫菊酯类和DDT的溶剂；粘合剂；橡胶胶水；飞机和模型的蒙布漆。对一些无机盐也是有效的分离剂，可从铀中分出钚，从钽分出铌，从铪分出锆。它的过氧化物是聚酯类树脂聚合反应中非常重要的引发剂。也用于有机合成工业。还可用作乙烯型树脂的抗凝剂和稀释剂。
        • {ALD} Merck:14,5207
        • {uni_hamburg} Short: II/27B
        • {ALD} Merck:14,5207
        • Beilstein:1,691
        • {uni_hamburg} Short: III/35E
          • 108-10-1 ME04932500 Methyl isobutyl ketone, reagent grade, ACS 甲基异丁基甲酮

          化学属性

          Mol. FormulaC6H12O
          Mol. Weight100.16
          Refractive index1.3940 to 1.3970
          Boiling Point117-118
          Density0.8
          Melting Point-84
          Flash Point17°C(lit.)
          TSCAYes
          Autoignition Point840 °F
          Vapor Density3.5 (vs air)
          Vapor Pressure15 mmHg ( 20 °C)
          Solubility微溶于水，易溶于多数有机溶剂。
          Stability对湿度敏感

          *以上化合物性质及应用等信息仅供参考