Potassium bis(trimethylsilyl)amide 双(三甲基硅基)氨基钾

规格: 1.0 M solution in THF, SpcSeal
CAS: 40949-94-8
产品编号: H12012
MDL: MFCD00010330
品牌: INFI
Chemical NamePotassium bis(trimethylsilyl)amide
Synonym 六甲基二硅氮烷 钾盐 溶液 双(三甲基硅基)氨基钾, 20% W/W, 0.91M IN THF 双(三甲基硅烷基)氨基钾 溶液 Potassium hexamethyldisilazide 六甲基二硅基胺基钾 溶液 六甲基二硅基胺基钾 溶液 六甲基二硅氮烷 钾盐 溶液
MDL NumberMFCD00010330
PubChem Substance ID3251421
Beilstein Registry Number4006754
EC Number424-100-2
CAS Number40949-94-8
Alfabeta NamePOTASSIUMBISTRIMETHYLSILYLAMIDE ()
Chemical Name Translation双(三甲基硅烷基)氨基钾
Reaxys-RN4006754
LabNetwork Molecule IDLN00163929
InChIInChI=1S/C6H18NSi2.K/c1-8(2,3)7-9(4,5)6;/h1-6H3;/q-1;+1
InChIKeyIUBQJLUDMLPAGT-UHFFFAOYSA-N
  • ⑴.常温常压条件下为液体。
  • ⑵.非亲核性强碱。
  • ⑶.医药中间体，主要用于合成头孢抗生素的生产。
  • 非亲核性强碱。
  • {ALF} Also used in the Wittig reaction, to give Li salt-free product distribution for selective (Z)-alkene formation: J. Org. Chem., 45, 4260 (1980). Has also been used with 18-crown-6 for selective formation of (Z)-ɑß-unsaturated esters from phosphonates: Tetrahedron Lett., 24, 4405 (1983).
  • {ALF} Sterically hindered strong base, compare Sodium bis(trimethyl­silyl)­amide, L13352 and Lithium bis(trimethyl­silyl)­amide, L15012. Used in the generation of K enolates, preferred to their Li or Na counterparts in some reactions, see e.g.: Tetrahedron Lett., 32, 1779 (1991); J. Am. Chem. Soc., 109, 6881 (1987); 111, 1063 (1989).
    • 40949-94-8 H12012 Potassium bis(trimethylsilyl)amide 双(三甲基硅基)氨基钾

    化学属性

    Mol. FormulaC6H18KNSi2
    Mol. Weight199.48
    Density0.9
    Refractive index1.4920
    Flash Point-14°(6°F)
    TSCANo
    Boiling Point66°
    Vapor Density3.2 (vs air)
    Vapor Pressure54 mmHg ( 25 °C)
    Stability对湿度敏感
    Danger-Level甲类
    pH-:A
    Redox-

    *以上化合物性质及应用等信息仅供参考