Hexadecy ltrimethyl ammonium bromide 十六烷基三甲基溴化铵

规格: 99%
CAS: 57-09-0
产品编号: H42775
MDL: MFCD00011772
品牌: INFI
Chemical NameHexadecyltrimethylammonium bromide, 99%, reagent grade
CAS Number57-09-0
Synonym ######## 1-hexadecyltrimethylammonium bromide BCTA CETRIMIDE CETRIMIDE PER USP CTMB Cetrimonium bromide Cetrimoniumbromid Cetyl trimethyl ammoniu Cetyltrimethyl ammonium bromide Cirrasol OD Cycloton V HEXADECYLTRIMETHYLAMMONIUM BROMIDE HTAB Hexadecyltri Lissolamine Micol Pollacid Trimethylcety Trimethylhexadecylammonium bromide acetoquatctab cetrimonium bromide (INN) cetyltrimethylamonium bromide hex hexadecyltrimethylammonium bromide palmityltrimethylammonium bromide {} {Chemicalbook {} {} {} {} {} {} { {} {} {} {} {} {} {Che {} {} {} {} {} {} {uni_hambu 三甲基十六烷基溴化 溴化三甲氨基十六脂 {Chemica
PubChem Substance ID5974
EC Number200-311-3
Beilstein Registry Number3598189
MDL NumberMFCD00011772
Reaxys-RN3598189
Merck Number2025
Chemical Name Translation十六烷基三甲基溴化铵
Wiswesser Line Notation16K1&1&1 &Q &E
LabNetwork Molecule IDLN00194021
InChIInChI=1S/C19H42N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(2,3)4;/h5-19H2,1-4H3;1H/q+1;/p-1
MDL NumberMFCD00011772
CAS Number57-09-0
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 410 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKYUA6 Yakkyoku.  Pharmacy.  (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo,
   Japan)  V.1-    1950-  Volume(issue)/page/year: 31,471,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCOC** Pesticide Chemicals Official Compendium, Association of the American
   Pesticide Control Officials, Inc., 1966.  (Topeka, KS)
   Volume(issue)/page/year: -,210,1966

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   28ZEAL "Pesticide Index," Frear, E.H., ed., State College, PA, College
   Science Pub., 1969  Volume(issue)/page/year: 5,40,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rode

TYPE OF TEST

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCOC** Pesticide Chemicals Official Compendium, Association of the American
   Pesticide Control Officials, Inc., 1966.  (Topeka, KS)
   Volume(issue)/page/year: -,210,1966

{hazard

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 35 mg/kg
SEX/DURATION            : female 8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 13,331,1975

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 35 mg/kg
SEX/DURATION            : female 12 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 13,331,1975

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 10500 ug/kg
SEX/DURATION            : female 8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - mus

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 10500 ug/kg
SEX/DURATION            : female 10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - craniofacial
   (including nose and tongue)
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 13,331,1975

WGK Germany3
Hazard Codes 9
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H302 Harmful if swallowed 吞食有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H318 Causes serious eye damage 严重伤害眼睛
  • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
    Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
    RTECSBQ7875000
    Precautionary statements
    • P201 Obtain special instructions before use. 使用前获取专门指示。
    • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
    • P273 Avoid release to the environment. 避免释放到环境中。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P301+P312+P330
    • P302+P350
    • P302+P352+P332+P313+P362+P364
    • P305+P351+P338
    • P332+P313
    • P337+P313
    • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Danger
      UN Number 3077 UN 3077 9/PG 3 UN3077
      Safety Statements
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
      • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
      • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
      • S39 Wear eye/face protection 戴眼睛/面孔保护装置;
      • S57 Use appropriate containment to avoid environmental contamination 使用适当容器避免环境污染;
      • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
      • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
        Risk Statements
        • R22 Harmful if swallowed 吞咽有害
        • R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
        • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
        • R48/22
        • R50 Very toxic to aquatic organisms 对水生生物极毒
          Storage condition Hygroscopic Store at RT. 密封保存。 易吸潮、密封保存。 充氩保存
          Packing GroupIII
          Hazard Class9
        • A cationic detergent used in the isolation of high molecular weight DNA.
        • {ALD} Merck:14,2025
        • Beilstein: 4,IV,819
        • {ALD} Merck:14,2025
        • {ALF} O-Alkylation of alcohols and phenols; see 2,6-Dimethyl­phenol, A11947. Surfactant-assisted permanganate oxidations: Can. J. Chem., 67, 1381 (1989). Reduction of alkyl halides to alkanes using zinc powder in micelles: Synth. Commun., 19, 1649 (1989). Control of ortho-para ratio in the bromination of anilines: Tetrahedron Lett., 30, 6209 (1989). Also facilitates ligand-free palladium salt-catalyzed Heck and Suzuki cross-coupling reactions in water: Tetrahedron Lett., 46, 3357 (2005).
        • {uni_hamburg} Short: III/31a
        • {TRC} Yu, H.-h., et al.: Gongneng Cailiao, 42,?2005 (2011),
        • {ALF} Surfactant-type catalyst (see Appendix 2) with many applications:
        • 57-09-0 H42775 Hexadecy ltrimethyl ammonium bromide	十六烷基三甲基溴化铵

          化学属性

          Mol. FormulaC19H42BrN
          Mol. Weight364.46
          Melting Point248-251
          TSCAYes
          Density1.013
          SolubilitySoluble in water (36.4 g/l) at 20 °C, methanol (>200 g/l) at 20 °C, alcohol (Very soluble), acetone (Slightly soluble), and chloroform. Insoluble in ether, benzene, and diethyl ether.
          Flash Point244°(471°F)
          Stability易吸潮
          Appearance powder 外观呈白色或浅黄色结晶体至粉末状,易溶于异丙醇,可溶于水,震荡时产生大量泡沫,能与阳离子、非离子、两性表面活性剂有良好的配伍性。
          Mol. FormulaC19H42BrN
          Mol. Weight364
          Appearance white solid
          Melting Point248-251