o-Chlorophenol 邻氯苯酚

规格: 99%
CAS: 95-57-8
产品编号: H67829
MDL: MFCD00002159
品牌: INFI
Chemical Name2-Chlorophenol
CAS Number95-57-8
PubChem Substance ID7245
EC Number202-433-2
Beilstein Registry Number1905114
MDL NumberMFCD00002159
Reaxys-RN1905114
Merck Number2154
Synonym 2-Chlorphenol 2-Chlorophenol Rcra waste number U048 2-chloro-pheno phenol, 2-chloro- 2-Chlor-1-hydroxybenzol RCRA waste number U048 2-氯苯酚,98+% 2-氯苯酚;邻氯苯酚;邻氯苯酚溶液;2-氯-1-羟基苯;2-羟基氯苯;邻羟基氯苯 2-chloro-1-hydroxybenzene CHLOROPHENOL(O-) 邻基(苯)酚 o-Chlorphenol 2-chloro-phenol Phenol, o-chloro- Phenol, o-chloro- 2-氯酚 2-氯-1-羟基苯 2-羟基氯苯 2-CHLOROPHENOL o-chlorophenicacid 2-chlorophenol(o-chlorophenol) o-Chlorophenic acid o-chloro-pheno 邻氯酚 pine-odisinfectant o-Chlorophenol rcrawastenumberu048 {Chemica
Chemical Name Translation2-氯苯酚
Wiswesser Line NotationQR BG
LabNetwork Molecule IDLN00200298
InChIInChI=1S/C6H5ClO/c7-5-3-1-2-4-6(5)8/h1-4,8H
GHS Symbol
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4800 mg/kg/12W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   19,413,1959

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 230 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 13,20,1958

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 950 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FEPRA7 Federation Proceedings, Federation of American Societies for
   Experimental Biology. (Bethesda, MD)  V.1-46, 1942-87.
   Volume(issue)/page/year: 2,76,1943

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 235 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 18,868,1975

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1580 mg/kg
TOXIC EFFECTS :
   Behavioral - food intake (animal)
   Lungs, Thorax, or Respiration - pulmonary emboli
   Liver - other changes
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Sci

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 800 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 182,135,1987

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 4550 mg/kg
SEX/DURATION            : female 70 day(s) pre-mating
                          female 1-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
   Reproductive - Effects on Newborn - stillbirth
REFERENCE :
   EVHPAZ EHP, Environmental Health Perspectives.  (U.S. Government Printing
   Office, Supt of Documents, Washington, DC 20402)  No.1-    1972-
   Volume(issue)/page/year: 46,137,1982

WGK Germany2
Hazard statements
  • H332 Harmful if inhaled 吸入有害
  • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
  • H302+H312+H332
  • H227 Combustible liquid 可燃液体
    Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
    Hazard Codes 6.1 Xn;N
    RTECSSK2625000
    Precautionary statements
    • P201 Obtain special instructions before use. 使用前获取专门指示。
    • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
    • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
    • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
    • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
    • P273 Avoid release to the environment. 避免释放到环境中。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P301+P330+P331+P310
    • P303+P361+P353
    • P303+P361+P353+P310+P363
    • P304+P340+P310
    • P305+P351+P338+P310
    • P308+P311
    • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
    • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
    • P403+P235
    • P405 Store locked up. 上锁保管。
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Warning
      UN Number 2021 2021/2905 UN 2021 6.1/PG 3 UN2021
      Risk Statements
      • R11 Highly flammable 非常易燃
      • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
      • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
      • R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性:吸入,皮肤接触和吞食都会产生十分严重的不可逆危险
      • R51/53
        Safety Statements
        • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
        • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
        • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
        • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
        • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
        • S7 Keep container tightly closed 保存在严格密闭容器中;
          Packing GroupIII
          Storage condition 密封避光保存。 0-6°C 储存温度2-8℃
          Hazard Class6.1
          Warnings 危化品目录(2015)
        • 有机合成,染料制造,杀菌剂。
        • {uni_hamburg} Short: II/25D
        • {ALD} Merck: 14,2154
        • Beilstein:6,183
        • {ALD} Merck: 14,2154
        • {uni_hamburg} Short: II/14a
        • {ALF} Has been used as a reagent for the protection of OH-groups in oligonucleotide synthesis. A study of various cleavage methods showed that the tetramethylguanidine salts of either 4-nitrobenzaldoxime or pyridine-2-carboxaldoxime gave the best results: Tetrahedron Lett., 2727 (1978).
        • 95-57-8 H67829 o-Chlorophenol
邻氯苯酚

          化学属性

          Mol. FormulaClC6H4OH
          Mol. Weight129
          Refractive index1.5570 to 1.5610
          Boiling Point175-176
          Density1.241
          Melting Point8
          Flash Point70°C(lit.)
          TSCAYes
          Solubility28.5 G/L (20 ºC)
          Stability对光敏感