Chemical Name | (Diacetoxyiodo)Benzene |
MDL Number | MFCD00008692 |
CAS Number | 3240-34-4 |
EC Number | 221-808-1 |
Beilstein Registry Number | 1879369 |
Synonym |
(Diacetoxyiodo)benzene
{LY} (Diacetoxyiodo)benzene
{} {LY} (Diacetoxyiodo)benzene
{} {} {LY} (Diacetoxyiodo)benzene
{} {} {} {LY} (Diacetoxyiodo)benzene
{} {} {} {} {LY} (Diacetoxyiodo)benzene
{} {} {} {} {} {LY} (Diacetoxyiodo)benzene
{} {} {} {} {} {} {LY} (Diacetoxyiodo)benzene
{} {} {} {} {} {} {} {LY} (Diacetoxyiodo)benzene
{} {} {} {} {} {} {} {} {LY} (Diacetoxyiodo)benzene
{} {} {} {} {} {} {} {} {} {LY} (Diacetoxyiodo)benzene
{} {} {} {} {} {} {} {} {} {}
{} {} {} {} {} {} {} {} {} {} {LY} (Diacetoxyiodo)benzene
{} {} {} {} {} {} {} {} {} {} {} {LY} (Diacetoxyiodo)benzene
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{} {} {} {} {} {} {} {} {} {} {} {} {LY} (Diacetoxyiodo)benzene
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{} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} (Diacetoxyiodo)benzene
{} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
{} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} (Diacetoxy |
PubChem Substance ID | 87571686 |
Chemical Name Translation | 碘苯二乙酸 |
Reaxys-RN | 1879369 |
Wiswesser Line Notation | 1VO-I-R &OV1 &5/10 |
InChIKey | ZBIKORITPGTTGI-UHFFFAOYSA-N |
LabNetwork Molecule ID | LN00190037 |
Canonical SMILES | O=C(OI(C1=CC=CC=C1)OC(C)=O)C |
Signal word |
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GHS Symbol
WGK Germany | 3 |
Safety Statements | |
- S22 Do not breathe dust 不要吸入粉尘;
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S37 Wear suitable gloves 戴适当手套;
- S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
- S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
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Risk Statements | |
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
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Precautionary statements | |
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P302+P352+P332+P313+P362+P364
- P305+P351+P338
- P305+P351+P338+P337+P313
- P332+P313
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
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RTECS | DA3525000 |
Storage condition |
2-8°C, protect from light
{LY} 2-8°C, protect from light
Light Sensitive
{} {LY} 2-8°C, protect from light
{} {} {LY} 2-8°C, protect from light
{} {} {} {LY} 2-8°C, protect from light
{} {} {} {} {LY} 2-8°C, protect from light
{} {} {} {} {} {LY} 2-8°C, protect from light
{} {} {} {} {} {} {LY} 2-8°C, protect from light
{} {} {} {} {} {} {} {LY} 2-8°C, protect from light
{} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light
{} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light
{} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light
{} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light
{} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light
{} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light
{} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light
{} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light
{} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect fro |
Personal Protective Equipment |
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
Hazard Codes |
Xi |
Hazard statements | |
- H315 Causes skin irritation 会刺激皮肤
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Packing Group | III |
Hazard Class | 6.1(b) |
UN Number |
1479 |
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
Volume(issue)/page/year: NX#02976
铑催化烯烃氮杂环丙烷磺酸酯氧化剂。
在常温下使用钯催化吲哚的2 - 芳基化
各种各样的杂环化合物合成的有用的试剂。
{ALF} For use in the Pd(II)-catalyzed functionalization of sp2 and sp3 C-H bonds, see: J. Am. Chem. Soc., 126, 2300 (2004).
{ALF} For a review of the ɑ-functionalization of carbonyl compounds by hypervalent iodine reagents, see: Contemp. Org. Synth., 2, 121 (1995).
{ALF} In the presence of triethyl orthoformate, aryl ethyl ketones undergo a rearrangement to ɑ-methyl arylacetates: Synthesis, 231 (1984):
{ALF} In combination with iodine, forms the acyl hypoiodite, which adds to alkenes: Bull. Chem. Soc. Jpn., 41, 1476 (1968), iodinates alkylbenzenes: J. Am. Chem. Soc., 90, 6187 (1968), and effects the decarboxylative iodination of aromatic carboxylic acids: Synth. Commun., 18, 1327 (1988).
{ALD} Beilstein: 5,IV,693
{ALF} For a brief feature on uses of the reagent in synthesis, see: Synlett, 657 (2006). For reviews of the use of polyvalent iodine compounds in organic synthesis, see: Synthesis, 709 (1984); Acc. Chem. Res., 19, 244 (1986); Chem. Rev., 96, 1123 (1996). For a monograph, see: A Varvoglis, The Organic Chemistry of Polycoordinated Iodine, VCH, N.Y. (1992).
{ALF} Versatile oxidizing and acetoxylating agent.
{ALF} Similarly, in the presence of an orthoformate and sulfuric acid, flavanones undergo a 1,2-aryl shift to give 2-aryl-2,3-dihydrobenzofuran-3-carboxylates: Bull. Chem. Soc. Jpn., 68, 1168 (1995). However, iodosobenzene diacetate alone oxidizes flavanones to flavones: J. Chem. Res. (Synop.), 213 (1995). For a review of the use of the reagent in heterocyclic synthesis, see: Synlett, 221 (1994).
{ALF} Treatment with aqueous NaOH gives the useful selective oxidant iodosobenzene (iodosylbenzene): Org. Synth. Coll., 5, 658 (1973).
{ALF} Converts primary aliphatic amides to amines, by Hofmann degradation: J. Org. Chem., 44, 1746 (1979); Synthesis, 266 (1981); 31 (1983). For use in the s
{ALF} Useful reagent for mild, rapid cleavage of 1,3-dithianes to the parent carbonyl compounds: Syn. Commun., 30, 4081 (2000).
{ALF} For a brief feature on uses of