Sodium bis(2-methoxyethoxy)aluminum hydrid 双(2-甲氧基乙氧基)氢化铝钠

规格: 70% w/w in toluene, SpcSeal
CAS: 22722-98-1
产品编号: H65682
MDL: MFCD00011631
品牌: INFI
Chemical NameSodium Bis(2-Methoxyethoxy)Aluminiumhydride
Synonym SODIUM BIS(2-METHOXYETHOXY)ALUMINIUM HYDRIDE Red-Al® 双(2-甲氧乙氧基)氢化铝钠 溶液 Sodium dihydro-bis-(2-methoxyethoxy)aluminate; RED-AL; SBAH SODIUM ALUMINUM HYDRIDE BIS(METHOXY-ETHOXIDE) SODIUM BIS(2-METHOXYETHOXY)ALUMINUM HYDRIDE SODIUM BIS(2-METHOXYETHOXY)ALUMINUM DIHYDRIDE Sodium dihydrobis(2-methoxyethoxy)aluminate sodium bis(2-methoxyethoxy)aluminum hydride solution sodium dihydrurobis(2-methoxyethoxy)aluminate VITRIDE(TM) 双(2-甲氧基乙氧基)氯酸钠, 70% W/W IN TOLUENE 双(2-甲氧基乙氧基)氢化铝钠(俗名红铝甲苯溶液) Sodium dihydro-bis-(2-methoxyethoxy)aluminate in toluene 双(2-甲氧基乙氧基)氯酸钠 RED-AL sodium dihydridobis(2-methoxyethanolato)aluminate(III)
MDL NumberMFCD00011631
PubChem Substance ID87575946
EC Number245-178-2
CAS Number22722-98-1
Merck Number8564
Chemical Name Translation二氢双(2-甲氧乙氧基)铝酸钠
Reaxys-RN6162081
LabNetwork Molecule IDLN00856564
GHS Symbol
WGK Germany2
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S43 In case of fire use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add -?Never use water) 着火时使用（指明具体的消防器材种类，如果用水增加危险，注明“禁止用水”
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S9 Keep container in a well-ventilated place 保持容器在通风良好的场所；
  • S30 Never add water to this product 切勿将水加入该产品中；
  • S20 When using do not eat or drink 使用时，不得进食，饮水；
  • S7/8 Keep container tightly closed and dry 保存在严格密闭容器中，保持干燥；
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾；
  • S33 Take precautionary measures against static discharges 对静电采取预防措施；
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
  • S4 Keep away from living quarters 远离生活区；
  • S46 If swallowed, seek medical advice immediately and show this container or label 食入时，立即求医并出示容器/标签；
  • S62 If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label where possible 吞食后不要催吐：立即求医并出示该容器或标签；
    Packing GroupI
    UN Number 3399
    Risk Statements
    • R11 Highly flammable 非常易燃
    • R14/15 Reacts violently with water, liberating extremely flammable gases 遇水剧烈反应，释放出高度可燃气体
    • R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
    • R48/20
    • R67 Vapours may cause drowsiness and dizziness 蒸汽可能导致嗜睡和昏厥
    • R65 Harmful: may cause lung damage if swallowed 若吞咽可能伤害肺部器官
    • R34 Causes burns 会导致灼伤
    • R20 Harmful by inhalation 吸入有害
    • R14 Reacts violently with water 遇水会猛烈反应
    • R17 Spontaneously flammable in air 在空气中能够自燃
      Storage condition Moisture Sensitive Flammables area Air & Moisture Sensitive 充氩保存
      Precautionary statements
      • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
      • P223 Keep away from any possible contact with water, because of violent reaction and possible flash fire. 远离任何与水接触的可能，因为会剧烈反应可能产生闪火。
      • P370+P378
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P422 Store contents under… 存储目录在…之下。
      • P231+P232
      • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
      • P403+P233
      • P305+P351+P338+P310
      • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
      • P301+P330+P331
      • P308+P313
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P305+P351+P338
      • P335+P334
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P301+P330+P331+P310
      • P201 Obtain special instructions before use. 使用前获取专门指示。
      • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
      • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
      • P304+P340+P310
      • P233 Keep container tightly closed. ?保持容器密闭。
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
      • P273 Avoid release to the environment. 避免释放到环境中。
      • P308+P311
      • P241+P242+P243
      • P303+P361+P353+P310+P363
        Signal word
        Hazard statements
        • H315 Causes skin irritation 会刺激皮肤
        • H304 May be fatal if swallowed and enters airways 吞食和进入呼吸道可能致命
        • H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
        • H311 Toxic in contact with skin 皮肤接触中毒
        • H301 Toxic if swallowed 吞食有毒
        • H318 Causes serious eye damage 严重伤害眼睛
        • H260 In contact with water releases flammable gases which may ignite spontaneously 与水接触时释放可燃气体，可自燃。
        • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
        • H361d Suspected of damaging the unborn child 怀疑对未出生婴儿造成伤害
        • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
        • H301+H311
          Hazard Codes F,C
          Hazard Class4.3/3
          Restrict -
        • 用于N-Boc氨基酸第二位胺的还原反应，生成手性胺。 是常用的还原试剂。Vitride 溶液的主要工业用途有：酯、酸、胺的还原，格林钠反应当活化和聚合的催化。＊应用：
        • Vitride红铝溶液是一个在有机化学体系中具有独特活性的溶剂溶解的还原剂。就大多数应用而言，Vitride红铝溶液都可以与氢化铝锂互换使用，并且Vitride红铝溶液易于处置，且具有高还原力，故在广泛系列的合成应用中得到大量使用。Vitride红铝溶液的主要工业用途有：有机官能团的还原，格林钠反应当活化和聚合的催化。我们就此以及其它用途可提供更详细的资料。
        • ＊典型反应：
        • ——羰基化合物
        • 可以容易地把醛类还原为相应的醇类。
        • 选择性地将α,β-不饱和醛类还原为不饱和醛类。
        • 　　选择性地还原α,β-不饱和酮类中的羰基。
        • 　　羧酸完全地还原为相应的醇类，还可在苯或甲苯中将酰胺类还原为醛类或胺类。酸酐类可被还原为相应的醇类。
        • 　　环酐类转化为二醇类。
        • 　　酯类进行局部还原可得相应的醛类，或进行完全还原成为醇类。
        • ——碳-氮化合物类
        • 　　芳香和杂芳香有机金属化合物的胺化可通过Vitride红铝溶液继还原而形成的叠氮化物而实现。
        • 　　Vitride 红铝溶液可以催化一系列的聚合物过程，包括
        • {ALF} The reducing properties can be modified by addition of one mole of ethanol, which gives a reagent for the reduction of lactones to lactols, or one mole of N-methylpiperazine or morpholine, which gives a reagent for the high-yield reduction of esters to aldehydes: Synthesis, 526 (1976).
        • {ALF} Convenient alternative to lithium aluminum hydride for many reductions: Coll. Czech. Chem. Commun., 34, 118 (1969). The reagent is more readily and safely handled, is more stable to air and can be used at high temperatures. For use in the stereospecific reduction of 2-yn-1-ols to (E)-allylic alcohols, and reviews, see: Org. Synth. Coll., 7, 524 (1990):
        • {ALD} Merck:14,8564
        • {ALF} For use as a superior activator/initiator for the formation of Grignard reagents, see: Coll. Czech. Chem. Commun., 38, 1614 (1973).
          • 22722-98-1 H65682 Sodium bis(2-methoxyethoxy)aluminum hydrid 双(2-甲氧基乙氧基)氢化铝钠

          化学属性

          Mol. FormulaC6H16AlNaO4
          Mol. Weight202.16
          Density1.036
          Flash Point4°C(lit.)
          TSCAYes
          Vapor Pressure21 mmHg ( 20 °C)
          Boiling Point110
          Solubility起反应
          Stability对光及湿度敏感
          RedoxReduction
          Danger-Level-
          pH-:-

          *以上化合物性质及应用等信息仅供参考