研峰科技 Infinity Scientific

Glycerol 甘油

规格: 99%

CAS: 56-81-5

产品编号: H73654

MDL: MFCD00004722

品牌: INFI

Chemical Name	Glycerol
CAS Number	56-81-5
Synonym	Glycerol {LY} Glycerol {} {LY} Glycerol {} {} {LY} Glycerol {} {} {} {LY} Glycerol {} {} {} {} {LY} Glycerol {} {} {} {} {} {LY} Glycerol {} {} {} {} {} {} {LY} Glycerol {} {} {} {} {} {} {} {LY} Glycerol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Glycerol {} {} {} {} {} {} {} {} {} {LY} Glycerol {} {} {} {} {} {} {} {} {} {} {LY} Glycerol {} {} {} {} {} {} {} {} {} {} {} {LY} Glycerol {} {} {} {} {} {} {} {} {} {} {} {} {LY} Glycerol {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Glycerol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Glycerol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Glycerol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Glycerol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Glycerol {} {} {} {} {} {} {} {} {} {} {} {} {
PubChem Substance ID	87575884
EC Number	200-289-5
Beilstein Registry Number	635685
MDL Number	MFCD00004722
Merck Number	4484
Chemical Name Translation	甘油
Reaxys-RN	635685
Wiswesser Line Notation	Q1YQ1Q
LabNetwork Molecule ID	LN00196493
Canonical SMILES	OCC(O)CO

GHS Symbol

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >570 mg/m3/1H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets.  (1810
   Frontage Rd., Northbrook, IL 60062)  Volume(issue)/page/year: 9-4/1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets.  (1810
   Frontage Rd., Northbrook, IL 60062)  Volume(issue)/page/year: 9-4/1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4090 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRZKAP Farmatsevtichnii Zhurnal (Kiev).  (V/O Mezhdunarodnaya Kniga, 113095
   Moscow, USSR) V.3-    1930-  Volume(issue)/page/year: (6),56,1977

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 7750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JIHTAB Journal of Industrial Hygiene and Toxicology.  (Cambridge, MA)
   V.18-31, 1936-49.  For publisher information, see AEHLAU.
   Volume(issue)/page/year: 23,259,1941

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DUR

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 200 mmol/L
REFERENCE :
   PNASA6 Proceedings of the National Academy of Sciences of the United States
   of America.  (National Academy of Sciences, Printing & Pub. Office, 2101
   Constitution Ave., Washington, DC 20418) V.1-    1915-
   Volume(issue)/page/year: 79,1171,1982

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 1 gm/kg
REFERENCE :
   TGANAK Tsitologiya i Genetika.  Cytology and Genetics.  For English
   translation, see CYGEDX. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-    1967-  Volume(issue)/page/year: 19,436,1985

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intratesticular
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 280 mg/kg
SEX/DURATION            : male 2 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   CCPTAY Contraception.  (Geron-X, Inc., POB 1108, Los Altos, CA 94022)  V.1-
   1970-  Volume(issue)/page/year: 29,291,1984

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intratesticular
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1600 mg/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - male fertility index (e.g. # males impregnating
   females per # males exposed to fertile nonpregnant females)
REFERENCE :
   CCPTAY Contraception.  (Geron-X, Inc., POB 1108, Los Altos, CA 94022)  V.1-
   1970-  Volume(issue)/page/year: 29,291,1984

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 100 mg/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   TGANAK Tsitologiya i Genetika.  Cytology and Genetics.  For English
   translation, see CYGEDX. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-    1967-  Volume(issue)/page/year: 19,436,1985

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intratesticular
SPECIES OBSERVED        : Primate - monkey
DOSE                    : 119 mg/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOX

WGK Germany	1
Personal Protective Equipment	Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US) Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) Eyeshields, Gloves
RTECS	MA8050000
Signal word	Danger Warning
Safety Statements
S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
Risk Statements
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性 R36 Irritating to eyes 刺激眼睛
Precautionary statements
P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。 P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。 P332+P313
Storage condition	2-8°C {LY} 2-8°C Hygroscopic {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
Hazard statements
H316 Causes mild skin irritation 会轻微的刺激皮肤 H332 Harmful if inhaled 吸入有害 H225 Highly flammable liquid and vapour 高度易燃液体和蒸气 H312 Harmful in contact with skin 皮肤接触有害 H302 Harmful if swallowed 吞食有害
Hazard Codes	F,Xn

气相色谱固定液(最高使用温度75℃，溶剂为甲醇)，分离分析低沸点含氧化物、胺类化合物、氮或氧杂环化合物，能完全分离3-甲基吡啶(沸点144.14℃)和4-甲基吡啶(沸点145.36℃)。适用于水溶液的分析。溶剂。

电泳级甘油用于样品制备和聚丙烯酰胺凝胶电泳凝胶的形成, 甘油（5-10％）增加了样品的密度，以至于使样品沉在在凝胶样品孔的底层。甘油也可以用来制备梯度凝胶,并可作为蛋白稳定剂和缓冲液组分。

{MCE} [2]. Yazdani SS, et al. Anaerobic fermentation of glycerol: a path to economic viability for the biofuelsindustry. Curr Opin Biotechnol. 2007 Jun;18(3):213-9.

{MCE} [3]. Huang ZH, et al. Expression and function of P-glycoprotein in rats with glycerol-induced acute renal failure. Eur J Pharmacol. 2000 Oct 20;406(3):453-60.

{TRC} Bartsch, W., et al.: Arzeim.-Forsch., 26, 1581 (1976),

{ALD} Merck:14,4484

Beilstein: 1,IV,2751

{uni_hamburg} Short: II/2

{uni_hamburg} Short: II/27B

{MCE} [1]. Pennings S, et al. Effect of glycerol on the separation of nucleosomes and bent DNA in low ionic strengthpolyacrylamide gel electrophoresis. Nucleic Acids Res. 1992 Dec 25;20(24):6667-72.

{MCE} [2]. Yazdani SS, et al. Anaerobic fermentation of glycerol: a path to

化学属性

Mol. Formula	C3H8O3
Mol. Weight	92.09
Refractive index	1.4700 to 1.4750
Boiling Point	290 °C at 760 mmHg
Density	1.25
Melting Point	20 °C
Flash Point	177°C(lit.)
TSCA	Yes
Autoignition Point	698 °F
Vapor Density	3.1 (vs air)
Vapor Pressure	<;1 mmHg ( 20 °C)
Solubility	可混溶于醇，与水混溶，不溶于氯仿、醚、油类。
Stability	易吸潮

*以上化合物性质及应用等信息仅供参考