Tributylphosphine 三丁基膦

规格: 98%，SpcSeal
CAS: 998-40-3
产品编号: H88825
MDL: MFCD00009462
品牌: INFI
Chemical NameTri-n-Butylphosphine
Synonym (n-C4H9)3P CYTOP(R) 340 P(n-Bu)3, TBP, Tris(trimethylsilyl)phosphane P(n-Bu)3, Tris(trimethylsilyl)phosphane PHOSPHINE, TRIBUTYL PHOSPHORUS TRI-N-BUTYL TBP TBUP TRI-N-BUTYLPHOSPHINE TRIBUTYL PHOSPHINE (CYTOP 340) CYTEC QUALITY TRIBUTYLPHOSPHINE Tri-n-butylphosphine Tri-n-butylphosphine,95% Tri-n-butylphosphine,99% Tri-n-butylphosphine,99%(10wt%inhexane) Tri-n-butylphosphine,min.93% Tributylfosfin Tributylphosphine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Beilstein Registry Number4(2)971
PubChem Substance ID13831
EC Number213-651-2
Chemical Name Translation三正丁基膦
Reaxys-RN1738261
LabNetwork Molecule IDLN00225102
InChIInChI=1S/C12H27P/c1-4-7-10-13(11-8-5-2)12-9-6-3/h4-12H2,1-3H3
MDL NumberMFCD00009462
CAS Number998-40-3
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academic Press, Inc., 1969  Volume(issue)/page/year: -,600,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academic Press, Inc., 1969  Volume(issue)/page/year: -,600,1969

WGK Germany3
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H250 Catches fire spontaneously if exposed to air 暴露于空气自发着火
  • H251 Self-heating: may catch fire 自我放热：可能着火
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H318 Causes serious eye damage 严重伤害眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
  • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
    Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
    RTECSSZ3270000
    Precautionary statements
    • P201 Obtain special instructions before use. 使用前获取专门指示。
    • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
    • P222 Do not allow contact with air. 不要与空气接触。
    • P231 Handle under inert gas. 在惰性气体中操作。
    • P233 Keep container tightly closed. ?保持容器密闭。
    • P235 Keep cool. 保持凉爽。
    • P235+P410
    • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
    • P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
    • P242 Use only non-sparking tools. 只能使用无火花工具。
    • P243 Take precautionary measures against static discharge. 采取预防措施，防止静电放电。
    • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P264+P265
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
    • P273 Avoid release to the environment. 避免释放到环境中。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P301+P312
    • P301+P317
    • P301+P330+P331
    • P301+P330+P331+P310
    • P302+P334
    • P302+P335+P334
    • P302+P352
    • P302+P361+P354
    • P303+P361+P353
    • P304+P340
    • P304+P340+P310
    • P305+P351+P338
    • P305+P351+P338+P310
    • P305+P354+P338
    • P308+P313
    • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
    • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
    • P316
    • P317
    • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
    • P322 Specific measures (see …on this label). 具体治疗（见本标签上的）。
    • P330 Rinse mouth. 漱口
    • P362+P364
    • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
    • P370+P378
    • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
    • P403+P235
    • P405 Store locked up. 上锁保管。
    • P407 Maintain air gap between stacks/pallets. 在堆叠/货板间保持气隙。
    • P410 Protect from sunlight. 防止阳光照射。
    • P413 Store bulk masses greater than … kg/…lbs at temperatures not exceeding … oC/…oF. 商店散装超过…kg/…lbs 时温度不应超过…oC/…oF.
    • P420 Store away from other materials. 远离其他材料。
    • P422 Store contents under… 存储目录在…之下。
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word
      Packing GroupI
      UN Number UN3254 3254
      Risk Statements
      • R51/53
      • R22 Harmful if swallowed 吞咽有害
      • R17 Spontaneously flammable in air 在空气中能够自燃
      • R34 Causes burns 会导致灼伤
      • R61 May cause harm to the unborn child 可能对未出生的婴儿导致伤害
      • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      • R21/22 Harmful in contact with skin and if swallowed 皮肤接触和不慎吞咽有害
      • R11 Highly flammable 非常易燃
      • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
        Safety Statements
        • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
        • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
        • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
        • S17 Keep away from combustible material 远离可燃物料；
        • S7 Keep container tightly closed 保存在严格密闭容器中；
        • S43 In case of fire use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add -?Never use water) 着火时使用（指明具体的消防器材种类，如果用水增加危险，注明“禁止用水”
          Storage condition 干燥，密封。 Air & Moisture Sensitive 充氩保存 2-8°C
          Hazard Codes T F,C Xi,F,C
          Hazard Class4.2
        • Usually used as catalyst for Domino reactions of activated conjugated dienes with β,γ?unsaturated-α-ketoesters, [3+2]-Cycloadditions,Umpolung addition reactions,Reductive carbonylation, Allylation reactions.
        • {ALF} A useful alternative to Triphenyl­phosphine, L02502 in many applications. Advantages include its greater reactivity and the water-solubility of the by-product phosphine oxide, simplifying its removal.
        • {ALF} Can behave as a hypernucleophilic catalyst in acylation reactions, with similar results to 4-(Dimethyl­amino)­pyridine, A13016: J. Am. Chem. Soc., 115, 3358 (1993).
        • {ALF} In combination with phenyl isocyanate and a Pd catalyst, converts cinnamyl alcohol directly to a phosphorane, which reacts with aldehydes to give conjugated dienes: Chem. Lett., 1449 (1988):
        • {ALF} Effective catalyst for the Baylis-Hillman reaction with less tendency than the usual DABCO (1,4-Diazabicyclo[2.2.2]octane, A14003) to promote aldol type side reactions: J. Org. Chem., 62, 1521 (1997).
        • {ALF} For example of its use in Mitsunobu-type reactions, see Diisopropyl­ azodicarboxyl­ate, L10386.
        • {ALD} Beilstein:4(2)971
          • 998-40-3 H88825 Tributylphosphine 三丁基膦

          化学属性

          Refractive index1.4590 to 1.4640
          Autoignition Point392 °F
          Vapor Density9 (vs air)
          SolubilityInsoluble in water. Miscible with ether, methanol, ethanol and benzene
          TSCAYes
          Melting Point-65
          Mol. FormulaC12H27P
          Mol. Weight202.32 g/mol
          Density0.817
          Flash Point99°F
          Appearance colorless liq. colorless to light yellow liq.
          Boiling Point110-115°C/10-12 mm
          Stabilityair sensitive
          Danger-Level乙类

          *以上化合物性质及应用等信息仅供参考