| Chemical Name | 3-Chloroperoxybenzoic Acid |
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| CAS Number | 937-14-4 |
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| Synonym |
3-Chloroperbenzoic Acid (Technical Grade, wet with water)
{} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {SNA} meta-Chloroperbenzoic acid
{} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {JNK} m-Chloroperbenzoic acid |
| EC Number | 213-322-3 |
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| Beilstein Registry Number | 9(4)972 |
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| MDL Number | MFCD00002127 |
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| PubChem Substance ID | 87565489 |
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| Reaxys-RN | 608317 |
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| Chemical Name Translation | 3-氯过氧化苯甲酸 |
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| Wiswesser Line Notation | QOVR CG |
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| LabNetwork Molecule ID | LN00195328 |
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| InChI | InChI=1S/C7H5ClO3/c8-6-3-1-2-5(4-6)7(9)11-10/h1-4,10H |
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| Signal word |
|
GHS Symbol
| WGK Germany | 3 |
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| Safety Statements | |
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- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
- S17 Keep away from combustible material 远离可燃物料；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
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| Risk Statements | |
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- R8 Contact with combustible material may cause fire 遇到易燃物会导致起火
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R5 Heating may cause an explosion 加热会引起爆炸
- R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
- R34 Causes burns 会导致灼伤
- R7 May cause fire 会导致起火
- R22 Harmful if swallowed 吞咽有害
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| Precautionary statements | |
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- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P220 Keep/Store away from clothing/…/combustible materials. 保持远离/贮存远离服装/....../可燃材料。
- P234 Keep only in original container. 只保留在原来的容器中。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P312+P330
- P302+P352+P312+P362+P364
- P304+P340+P312
- P305+P351+P338
- P305+P351+P338+P337+P313
- P332+P313
- P410 Protect from sunlight. 防止阳光照射。
- P411+P235
- P412 Do not expose to temperatures exceeding 50 oC/ 122 oF. 不要暴露在超过50 oC / 122 oF的温度。
- P420 Store away from other materials. 远离其他材料。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
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| Hazard statements | |
|---|
- H242 Heating may cause a fire 加热可能会引起火灾
- H315 Causes skin irritation 会刺激皮肤
- H317 May cause an allergic skin reaction 可能导致皮肤过敏
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
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| Personal Protective Equipment |
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
| RTECS | SD9470000 |
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| Packing Group | II |
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| UN Number |
2755/3106 |
| Hazard Codes |
O,Xi,C |
| Storage condition |
0-10
0-10°C
2-8°C
4
储存温度2-8°C |
| Hazard Class | 5.2 |
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| Warnings |
危化品目录(2015) |
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 21 gm/kg/52W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Skin and Appendages - tumors
Tumorigenic - tumors at site of application
REFERENCE :
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60,
1940-78. For publisher information, see JJIND8. Volume(issue)/page/year:
55,1359,1975
| Restrict |
危险品 |
它广泛用于环化反应，如碳-碳双键发生立体反应；Baeyer-Villiger氧化反应，如羰基化合物与过氧酸反应生成酯等；N-氧化反应，如胞嘧啶，胞啶用它反应可分别得到收率21.4%和41%的N-氧化物.它也可作为合成医药，农药等精细化工产品的 氧 化剂使用；另外有时也用作漂白剂。
{ALF} Sulfides can be oxidized selectively either to sulfoxides or sulfones: Tetrahedron, 22, 1235 (1966); J. Chem. Soc. (C), 2720 (1969); J. Org. Chem., 35, 2106 (1970).
{ALF} Reagent for epoxidation of alkenes: J. Org. Chem., 29, 1976 (1964). Dichloromethane has been recommended as solvent for these reactions, since the peracid is soluble, but the by-product, 3-chlorobenzoic acid, is almost insoluble. For high-yield, stereospecific epoxidation in a two-phase, almost neutral system, see: J. Org. Chem., 44, 1351 (1979). For regioselective epoxidation of the more substituted double bond of a diene, see: Org. Synth. Coll., 5, 467 (1973). For epoxidation in aqueous solution followed by in situ hydrolysis to the trans-diol by 10% sulfuric acid, see: Synth. Commun., 19, 1939 (1989).
{ALD} Beilstein:9(4)972
{ALF} Primary aliphatic amines are oxidized to nitro-compounds: J. Org. Chem., 31, 524 (1966). Good yields are obtained in 1,2-dichloroethane solution: J. Org. Chem., 44, 659 (1979); 54, 2869 (1989).
{ALF} For the stereospecific oxidation of imines to oxaziridines under phase-transfer conditions, see: Org. Synth. Coll., 8, 546 (1993):
{ALF} Perfluorooxaziridines have been prepared using acetonitrile as solvent: J. Org. Chem., 58, 4754 (1993).
{ALF} For a brief feature on uses of this reagent in Organic synthesis, see: Synlett, 664 (2007).
{ALF} WARNING: The reagent has been reported to react exothermically with DMF: Org. Process Res. Dev., 6, 159 (2004).
{ALF} Carbonyl compounds undergo the Baeyer-Villiger reaction to give esters or lactones: J. Org. Chem., 29, 2914 (1964). For an extensive review of the Baeyer-Villiger reaction, see: Org. React., 43, 251 (1993).
