研峰科技 Infinity Scientific

L-GlutamineL-谷氨酰胺

规格:

CAS: 56-85-9

产品编号: Bellen10013981

MDL: MFCD00008044

品牌: Bellen

Chemical Name	L-Glutamine
CAS Number	56-85-9
Synonym	L-Glutamine {LY} L-Glutamine {} {LY} L-Glutamine {} {} {LY} L-Glutamine {} {} {} {LY} L-Glutamine {} {} {} {} {LY} L-Glutamine {} {} {} {} {} {LY} L-Glutamine {} {} {} {} {} {} {LY} L-Glutamine {} {} {} {} {} {} {} {LY} L-Glutamine {} {} {} {} {} {} {} {} {LY} L-Glutamine {} {} {} {} {} {} {} {} {} {LY} L-Glutamine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Glutamine {} {} {} {} {} {} {} {} {} {} {} {LY} L-Glutamine {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Glutamine {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Glutamine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Glutamine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Glutamine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Glutamine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} L-Glutamine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
MDL Number	MFCD00008044
EC Number	200-292-1
Beilstein Registry Number	1723797
PubChem Substance ID	87570277
Merck Number	4471
Reaxys-RN	1723797
Chemical Name Translation	L-谷氨酰胺
Wiswesser Line Notation	ZV2YZVQ
LabNetwork Molecule ID	LN00196058
InChI	InChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
Canonical SMILES	N[C@@H](CCC(N)=O)C(O)=O

GHS Symbol

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 27 mg/kg/1W-I
TOXIC EFFECTS :
   Behavioral - euphoria
REFERENCE :
   AJPSAO American Journal of Psychiatry.  (American Psychiatric Assoc.,
   Circulation Dept., 1400 K St., NW, Washington, DC 20005)  V.78-    1921-
   Volume(issue)/page/year: 141,1302,1984

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 21700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,228,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 7500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,228,1982

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 10 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 372,75,1996

Signal word	Warning
WGK Germany	1
Safety Statements
S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触； S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
Risk Statements
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性 R36 Irritating to eyes 刺激眼睛
Precautionary statements
P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
RTECS	MA2275100
Personal Protective Equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage condition	2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Hazard Codes	Xi

生化研究，细菌培养基。

{MCE} [2]. Mary Corless , et al. Glutamine Regulates Expression of Key Transcription Factor, Signal Transduction, Metabolic Gene, and Protein Expression in a Clonal Pancreatic Beta-Cell Line. J Endocrinol. 2006 Sep;190(3):719-27.

{ALD} Merck:14,4471

Beilstein:4,491

{TRC} Rivett, A., et al.: J. Biol. Chem., 260, 300 (1985),

{uni_hamburg} Short: EINECS

{uni_hamburg} Short: III/20a

{uni_hamburg} Short: III/5a

{MCE} [1]. Newsholme P, et al. Glutamine and glutamate as vital metabolites. Braz J Med Biol Res. 2003 Feb;36(2):153-63. Epub 2003 Jan 29.

56-85-9 Bellen10013981 L-GlutamineL-谷氨酰胺

化学属性

Mol. Formula	C5H10N2O3
Mol. Weight	146.14
Density	1.321
Melting Point	185°C
TSCA	Yes
Flash Point	223.3±27.3 °C
Appearance	D 20 +32°(0.5-2 mg/ml，1 mol/L盐酸中)。 +6.1°(0.5-2 mg/ml，水中)，[α] 无色针状结晶物；无臭无味；溶于水(25℃水中溶解度为3.6%)，微溶于乙醇，不溶于乙醚、甲醇、苯、丙酮、氯仿、乙酸乙酯和冰乙酸；遇热、酸、碱不稳定，易水解为L-谷氨酸；pI5.65，分解点为185-186℃；比旋光度[α] solution 23
Refractive index	6.8 ° (C=4, H2O)
Solubility	Soluble in water (35 mg/ml at 20 °C), DMSO (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C). Insoluble in methanol, and ether.
Boiling Point	445.6°C at 760mmHg

*以上化合物性质及应用等信息仅供参考