Chemical Name | Lepidine |
CAS Number | 491-35-0 |
Alfabeta Name | LEPIDINE |
MDL Number | MFCD00006784 |
Synonym |
4-Methylquinoline
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EC Number | 207-734-2 |
Beilstein Registry Number | 110926 |
PubChem Substance ID | 87571993 |
Merck Number | 5441 |
Chemical Name Translation | 4-甲基喹啉 |
Reaxys-RN | 110926 |
Wiswesser Line Notation | T66 BNJ E1 |
LabNetwork Molecule ID | LN00171532 |
InChI | InChI=1S/C10H9N/c1-8-6-7-11-10-5-3-2-4-9(8)10/h2-7H,1H3 |
Canonical SMILES | Cc1ccnc2ccccc12 |
Warnings |
危化品目录(2015)
IRRITANT |
Signal word |
Warning |
GHS Symbol
WGK Germany | 3 |
Safety Statements | |
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36 Wear suitable protective clothing 穿戴适当的防护服;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
|
Risk Statements | |
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
|
Precautionary statements | |
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P302+P352+P332+P313+P362+P364
- P305+P351+P338
- P305+P351+P338+P337+P313
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
|
Hazard statements | |
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
|
Personal Protective Equipment |
Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
RTECS | OH0316000 |
Storage condition |
+4°C
+4℃
4
4℃
Store at room temperature
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Hazard Codes |
Xn
Xi
Xi,Xn |
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 1 umol/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 42,335,1977
TYPE OF TEST : Unscheduled DNA synthesis
TEST SYSTEM : Rodent - rat Liver
DOSE/DURATION : 1 mmol/L
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
Volume(issue)/page/year: 12,217,1991
Restrict |
危险品 |
用作染料、医药、感光材料的中间体。
{uni_hamburg} Short: II/27B
{ALF} Lepidine and similar compounds can be alkylated at the 2-position by free radicals generated by the action of t-butyl hydroperoxide and a salt of Fe(II) on a primary or secondary alkyl iodide: Acta Chem. Scand., 43, 995 (1989). Similarly, 2-formylation can be achieved in high yield using 1,3,5-trioxane in the presence of TFA, t-BuOOH and FeSO4 in acetonitrile: J. Org. Chem., 51, 536 (1986).
{ALD} Merck: 14,5441
Beilstein:20,395
{uni_hamburg} Short: III/35B
{ALD} Merck: 14,5441