7-Hydroxycoumarin 7-羟基香豆素

规格: 98%
CAS: 93-35-6
产品编号: H14472
MDL: MFCD00006878
品牌: INFI
Chemical Name7-Hydroxycoumarin
CAS Number93-35-6
Alfabeta NameHYDROXYCOUMARINE 7-
MDL NumberMFCD00006878
EC Number202-240-3
Beilstein Registry Number18,27
Synonym 伞形酮 7-羟基-2H-1-苯并吡喃-2-酮 7-羟基香豆素 7-Hydroxycoumarin
PubChem Substance ID5281426
Merck Number9847
Chemical Name Translation7-羟基香豆素
Reaxys-RN127683
Wiswesser Line NotationT66 BOVJ IQ
LabNetwork Molecule IDLN00174498
InChIInChI=1S/C9H6O3/c10-7-3-1-6-2-4-9(11)12-8(6)5-7/h1-5,10H
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 18,1330,1968

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Klebsiella pneumoniae
DOSE/DURATION           : 800 mg/L
REFERENCE :
   JIMMBG Journal of Immunological Methods.  (Elsevier Science Pub. Co., Inc.,
   52 Vanderbilt Ave., New York, NY 10017)  V.1-    1971-
   Volume(issue)/page/year: 36,55,1980

Warnings IRRITANT
Signal word
WGK Germany3
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
  • S37 Wear suitable gloves 戴适当手套；
    Risk Statements
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      Precautionary statements
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P305+P351+P338
      • P302+P352+P332+P313+P362+P364
      • P305+P351+P338+P337+P313
        Hazard statements
        • H315 Causes skin irritation 会刺激皮肤
        • H319 Causes serious eye irritation 严重刺激眼睛
        • H335 May cause respiratory irritation 可能导致呼吸道刺激
          RTECSGN6820000
          Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
          Hazard Codes Xi
        • An intracellular pH sensitive fluorescent indicator & bloodbrain barrier probe
        • {ALF} Fluorescent indicator.
        • {ALD} Merck: 14,9847
        • {ALD} Merck: 14,9847
        • Beilstein:18,27
        • {MCE} [1]. Yu SM, et al. Umbelliferone exhibits anticancer activity via the induction of apoptosis and cell cycle arrest in HepG2 hepatocellular carcinoma cells. Mol Med Rep. 2015 Sep;12(3):3869-3873.
          • 93-35-6 H14472 7-Hydroxycoumarin 7-羟基香豆素

          化学属性

          Mol. FormulaC9H6O3
          Mol. Weight162
          Density1.403
          Melting Point230
          TSCANo
          SolubilitySoluble in water (slightly at 20 °C), 95% ethanol (50 mg/ml), chloroform, acetone, and methanol.

          *以上化合物性质及应用等信息仅供参考