Ethyl Lactate 乳酸乙酯

规格: 98%
CAS: 97-64-3
产品编号: H15514
MDL: MFCD00065359
品牌: INFI
Chemical NameEthyl Lactate
CAS Number97-64-3
Alfabeta NameETHYLHYDROXYPROPANOATE 2-
MDL NumberMFCD00065359
Synonym (±)-Ethyl lactate (±)-Lactic acid ethyl ester (±)-Milchsäureethylester 1-hydroxyethanecarboxylicacid,ethylester 2-Hydroxypropanoic acid ethyl ester 2-Hydroxypropionic acid ethyl ester, Lactic acid ethyl ester 2-hydroxy-propanoic acid ethyl ester Acytol DL-Ethyllactat ETHYL 2-HYDROXYPROPIONATE Ethyl rac-lactate Ethyl alpha-hydroxypropionate Ethyl ester of lactic acid Ethyl lactate 98+ Ethyl-2-hydroxypropanat Ethyl-2-hydroxypropanoat L-Lactic acid ethyl ester Lactic acid ethyl ester; 2-Hydroxy-propanoic acid ethyl ester Lactic acid-ethyl ester {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
EC Number202-598-0
Merck Number3817
Beilstein Registry Number3(4)643
PubChem Substance ID7344
Reaxys-RN1209448
Chemical Name Translation乳酸乙酯
Wiswesser Line NotationQVY1&O2
LabNetwork Molecule IDLN00193556
InChIInChI=1S/C5H10O3/c1-3-8-5(7)4(2)6/h4,6H,3H2,1-2H3
Canonical SMILESCC(O)C(OCC)=O
GHS Symbol
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - cyanosis
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 11,150,1959

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 65,89,1939

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 2605 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 76,189,1942

TYPE OF TEST

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year

Warnings 危化品目录(2015) IRRITANT
RTECSOD5075000
UN Number
Risk Statements
    Safety Statements
    • S39 Wear eye/face protection 戴眼睛/面孔保护装置；
    • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
    • S24 Avoid contact with skin 避免皮肤接触；
      Packing GroupIII
      Hazard Codes
      WGK Germany1
      Hazard statements
      • H226 Flammable liquid and vapour 易燃液体和蒸气
      • H318 Causes serious eye damage 严重伤害眼睛
      • H335 May cause respiratory irritation 可能导致呼吸道刺激
        Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
        Precautionary statements
        • P304+P340+P312
        • P501 Dispose of contents/container to..… 处理内容物/容器.....
        • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
        • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
        • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
        • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
        • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
        • P304+P340
        • P303+P361+P353
        • P403+P233
          Signal word
          Hazard Class3
          Restrict 危险品
          Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature
        • {ALF}
        • {uni_hamburg} Short: III/47
        • {uni_hamburg} Short: III/38B
        • {ALF} Silylation followed by reaction with MeLi gives a useful chiral synthon. For preparation and discussion of reactivity, see: Org. Synth. Coll., 9, 139 (1998):
        • {ALF} For reaction with Diphenyl­phosphonic azide, A12124, in the prepartaion, with inversion, of ethyl (R)-2-azidopropionate, see: Org. Synth., 75, 31 (1997).
        • {ALF} Ethyl (or isobutyl) L-lactate adds to aryl methyl ketenes to give esters of 2-arylpropionic acids in which the chirality is transferred to the new chiral center to a surprising degree: J. Am. Chem. Soc., 111, 7650 (1989):
          • 97-64-3 H15514 Ethyl Lactate 乳酸乙酯

          化学属性

          Mol. FormulaC5H10O3
          Mol. Weight118.13
          Density1.011
          Refractive index1.4110 to 1.4140
          Flash Point46 °C - 闭杯
          TSCAYes
          Boiling Point154 °C - lit
          Melting Point-26 °C
          Appearance 14 为-10°。易溶于乙醇、丙酮、乙醚、酯类等有机溶剂，与水混溶时有部分水解。小白鼠经口LD 2.5g/kg，ADI 无需特殊规定（FAO/WHO，1994）。 d 50 无色至微黄色透明液体，具有朗姆酒、水果和奶油的香气。凝固点-25℃，沸点154℃，比旋光度[a]

          *以上化合物性质及应用等信息仅供参考