4-Nitrobenzyl Alcohol 对硝基苯甲醇

规格: 97%
CAS: 619-73-8
产品编号: H22407
MDL: MFCD00007376
品牌: INFI
Chemical Name4-Nitrobenzyl Alcohol
CAS Number619-73-8
Alfabeta NameNITROBENZYLALCOHOL 4-
MDL NumberMFCD00007376
Beilstein Registry Number1424026
PubChem Substance ID69275
EC Number210-611-6
Reaxys-RN1424026
Synonym 1-Hydroxymethyl-4-nitrobenaene 4-NITROBENZYL ALCOHOL 4-nitrobenzenemethanol Benzyl alcohol, p-nitro- p-(Hydroxymethyl)nitrobenzene p-Nitrobenzyl alcohol 對硝苄醇
Chemical Name Translation对硝基苯甲醇
LabNetwork Molecule IDLN00173641
InChIInChI=1S/C7H7NO3/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4,9H,5H2
GHS Symbol
TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - hamster Embryo
DOSE/DURATION           : 200 umol/L
REFERENCE :
   CALEDQ Cancer Letters (Shannon, Ireland).  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1975- Volume(issue)/page/year:
   52,203,1990

Warnings IRRITANT
Signal word Warning {} {} {} {} {} {} {} {TCI}
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H302 Harmful if swallowed 吞食有害
    WGK Germany3
    RTECSDP0657100
    Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
    Safety Statements
    • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
    • S37 Wear suitable gloves 戴适当手套；
    • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
    • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
    • S22 Do not breathe dust 不要吸入粉尘；
      Risk Statements
      • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      • R22 Harmful if swallowed 吞咽有害
        Precautionary statements
        • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
        • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
        • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
        • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
        • P305+P351+P338
        • P332+P313
        • P305+P351+P338+P337+P313
        • P302+P350
        • P337+P313
        • P302+P352+P332+P313+P362+P364
          Hazard Codes Xi Xn
          Storage condition Store at RT.
        • 有机合成中间体。
        • {uni_hamburg} Short: III/35D2
        • {ALF} Protection of alcohols as their 4-nitrobenzyl ethers has been carried out, e.g. in the presence of trifluoroacetic anhydride and 2,6-lutidine: Tetrahedron Lett., 31, 389 (1990).
        • {ALD} Beilstein:6,450
        • {ALF} Selective deprotection at room temperature can be accomplished by sodium dithionite in aqueous acetonitrile: Synth. Commun., 12, 219 (1982). Photolytic cleavage has been employed in the carbohydrate series: J. Org. Chem., 37, 2281, 2285 (1972). For reviews of photoremovable protecting groups, see: Synthesis, 1 (1980); Org. Photochem., 9, 225 (1987). Reduction to the aniline, followed by chemical or electrolytic oxidation has also been reported: Tetrahedron Lett., 31, 389 (1990).
        • {ALF} Has also found use to protect carboxylic acids as their 4-nitrobenzyl esters, particularly in the penicillin and peptide fields. See also 4-Nitrobenzyl­ bromide, A15236, and 4-Nitrobenzyl­ chloride, A15749.
          • 619-73-8 H22407 4-Nitrobenzyl Alcohol 对硝基苯甲醇

          化学属性

          Mol. FormulaO2NC6H4CH2OH
          Mol. Weight153
          Boiling Point185
          Melting Point92-94
          Density1.422
          Flash Point180°(356°F)
          TSCAYes
          Appearance 淡黄色晶体。熔点92-93℃，沸点185℃（1.6kPa），闪点180℃。易溶于乙醇、乙醚，微溶于水。

          *以上化合物性质及应用等信息仅供参考