1,2-Dichloropropane 1,2-二氯丙烷

规格: 98%
CAS: 78-87-5
产品编号: H27652
MDL: MFCD00000868
品牌: INFI
Chemical Name1,2-Dichloropropane
Synonym CH3CON(CH3)2 Pr bichloruredepropylene n,n-dimethylacetamides { 1,2-二氯丙烷;氯化丙烯 (±)-1,2-dichloro-propane {Chemica 1,2-二氯丙烷 {Chemi 1,2-Dichlorpropan {Chemicalb SK 7176 PROPYLENE DICHLORIDE 乙酰二甲胺 Chlorinated C3 hydrocarbons bichloruredepropylene(french) 1,2-Dichloropropane Acetic acid dimethylacetamide NSC 3138 Bichlorure de propylene B 二氯丙烷 α,β-Dichloropropane nsc3138 N-乙酰二甲胺 {C N,N-二甲基乙酰胺, HPLC GRADE, 99.5+% 氯化丙烯 D-d Mixture alpha,beta-Propylene dichloride dichloro-1,2-propane NCI-C55141 1,2-二氯丙烷, 98%
MDL NumberMFCD00000868
CAS Number78-87-5
PubChem Substance ID87567081
EC Number201-152-2
Beilstein Registry Number1(4)195
Merck Number7854
Reaxys-RN1718880
Chemical Name Translation1,2-二氯丙烷
Wiswesser Line NotationGY1&1G
LabNetwork Molecule IDLN00223891
GHS Symbol
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 130 gm/kg/2Y-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-263,1986

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Behavioral - sleep
   Liver - other changes
REFERENCE :
   AJHYA2 American Journal of Hygiene.  (Baltimore, MD)  V.1-80, 1921-64.  For
   publisher information, see AJEPAS.  Volume(issue)/page/year: 16,325,1932

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 960 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - ulceration or bleeding from stomach
   Gastrointestinal - ulceration or bleeding from small intestine
REFERENCE :
   ESKGA2 Eisei Kagaku.  Hygienic Chemistry.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  V.1-    1953-
   Volume(issue)/page/year: 28,P31,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rod

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FMCHA2 Farm Chemicals Handbook.  (Meister Pub., 37841 Euclid Ave.,
   Willoughy, OH 44094)  Volume(issue)/page/year: -,C253,1991

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 860 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,98,1986

TYPE OF TEST            : LCLo - Lowest

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 ug/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 5(Suppl
   1),3,1983

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 11600 ug/L
REFERENCE :
   SCIEAS Science.  (American Assoc. for the Advancement of Science, 1333 H
   St., NW, Washington, DC 20005)  V.1-    1895-  Volume(issue)/page/year:
   236,933,1987

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 660 mg/L
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-263,1986

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 3300 umol/L
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 9,401,1987

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 113 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   10(Suppl 10),1,1987

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 1950 mg/kg
SEX/DURATION            : female 7-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - other effects
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   28,18,1995

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1250 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - other effects
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   28,18,1995

WGK Germany3
Hazard statements
  • H332 Harmful if inhaled 吸入有害
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H302 Harmful if swallowed 吞食有害
  • H302+H332
    Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
    RTECSTX9625000
    Precautionary statements
    • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P305+P351+P338
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
    • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
    • P301+P312+P330
    • P337+P313
    • P403+P233
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P303+P361+P353
    • P201 Obtain special instructions before use. 使用前获取专门指示。
    • P302+P352+P333+P313+P362+P364
    • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
    • P233 Keep container tightly closed. ?保持容器密闭。
    • P304+P340+P312
    • P273 Avoid release to the environment. 避免释放到环境中。
    • P305+P351+P338+P337+P313
    • P308+P311
      Signal word
      Packing GroupII
      UN Number 1279
      Risk Statements
      • R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
      • R11 Highly flammable 非常易燃
      • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
      • R23/25 Toxic by inhalation and if swallowed 吸入及吞食都有毒
      • R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性:吸入,皮肤接触和吞食都会产生十分严重的不可逆危险
      • R61 May cause harm to the unborn child 可能对未出生的婴儿导致伤害
      • R20/21 Harmful by inhalation and in contact with skin 吸入及与皮肤接触有害
        Safety Statements
        • S24 Avoid contact with skin 避免皮肤接触;
        • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
        • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
        • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
        • S2 Keep out of the reach of children 避免儿童触及;
          Hazard Codes F,Xn,T
          Storage condition 0-6°C Refrigerator 储存温度2-8℃ 密封阴凉保存。 0-10°C 0-10
          Hazard Class3
          Warnings 危化品目录(2015) 危险化学品
        • 油类和脂肪的溶剂。干洗剂。脱脂剂。杀虫熏蒸混合剂。
        • {uni_hamburg} Short: II/25C
        • {uni_hamburg} Short: III/20a
        • {uni_hamburg} Short: II/5
        • {ALD} Merck: 14,7854
        • 78-87-5 H27652 1,2-Dichloropropane
1,2-二氯丙烷

          化学属性

          Mol. FormulaC3H6Cl2
          Mol. Weight113
          Autoignition Point1035 °F
          Refractive index1.4380 to 1.4400
          Vapor Density3.89 (vs air)
          Boiling Point97°C
          Vapor Pressure40 mmHg ( 19.4 °C)
          Density1.156
          Melting Point-100°C
          Flash Point14°C(lit.)
          TSCAYes
          Solubility3 G/L (20 ºC)
          Appearance 无色透明液体,可燃。能与水、醇、醚、酯、苯、三氯甲烷和芳香化合物等有机溶剂任意混合。冰点-20℃,沸点166℃,96℃(10.7kPa),85-87℃(4.4kPa),74-74.5℃(3.47kPa),66-67℃(2.0kPa),62-63℃(1.6kPa),相对密度0.9366(25/4℃),0.9599(0/4℃),折射率1.4380。闪点(开杯)70℃。

          *以上化合物性质及应用等信息仅供参考