L-Glutamine L-谷氨酰胺

规格: 99%
CAS: 56-85-9
产品编号: H35534
MDL: MFCD00008044
品牌: INFI
Chemical NameL-Glutamine
CAS Number56-85-9
Synonym L-谷氨酸酰胺 {uni_hamburg} L-G L-麸氨酰胺 H-GLN-OH Glumin Levoglutamide Glutamic acid 5-amide L-2-Aminoglutaramidic Acid Pentanoic acid, 2,5-diamino-5-oxo-, (S)- L-(+)-Glutaminsäure-5-amid L-Glutamid L 谷氨酸 Cebrogen H-Gln-OH γ-Glutamine (S)-(+)-GLUTAMINE L-Glutaminsäure-5-a { L-Glutamide L-谷氨酰胺, 99% (S)-(+)-Glutamin L-GLUTAMINE L-谷氨酸AJI88,USP23,FCCIII,CP2000 L-谷氨酰胺溶液 200mM 氨羰基丁氨酸 L-GLN (S)-2,5-DIAMINO-5-OXOPENTANOIC ACID 2-AMINOGLU {C (S)-2,5-Diamino-5-oxopentanoic acid levoglut Glutamic acid amide
MDL NumberMFCD00008044
EC Number200-292-1
Beilstein Registry Number4,491
PubChem Substance ID87570277
Merck Number4471
Reaxys-RN1723797
Chemical Name TranslationL-GlutamineL-谷氨酰胺
Wiswesser Line NotationZV2YZVQ
LabNetwork Molecule IDLN00196058
InChIInChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
GHS Symbol
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 27 mg/kg/1W-I
TOXIC EFFECTS :
   Behavioral - euphoria
REFERENCE :
   AJPSAO American Journal of Psychiatry.  (American Psychiatric Assoc.,
   Circulation Dept., 1400 K St., NW, Washington, DC 20005)  V.78-    1921-
   Volume(issue)/page/year: 141,1302,1984

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 21700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,228,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 7500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,228,1982

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 10 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 372,75,1996

Signal word Warning
WGK Germany1
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
    Risk Statements
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
    • R36 Irritating to eyes 刺激眼睛
      Precautionary statements
        RTECSMA2275100
        Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
        Storage condition 室温保存 -20°C
        Hazard Codes Xi
      • 生化研究,细菌培养基。
      • {uni_hamburg} Short: III/20a
      • {ALD} Merck:14,4471
      • Beilstein:4,491
      • {uni_hamburg} Short: EINECS
      • {TRC} Rivett, A., et al.: J. Biol. Chem., 260, 300 (1985),
      • {ALD} Merck:14,4471
      • {uni_hamburg} Short: III/5a
      • 56-85-9 H35534 L-Glutamine	L-谷氨酰胺

        化学属性

        Mol. FormulaC5H10N2O3
        Mol. Weight146.15
        Density1.321
        Melting Point185
        TSCAYes
        Flash Point185°C
        Appearance D 20 +32°(0.5-2 mg/ml,1 mol/L盐酸中)。 +6.1°(0.5-2 mg/ml,水中),[α] 无色针状结晶物;无臭无味;溶于水(25℃水中溶解度为3.6%),微溶于乙醇,不溶于乙醚、甲醇、苯、丙酮、氯仿、乙酸乙酯和冰乙酸;遇热、酸、碱不稳定,易水解为L-谷氨酸;pI5.65,分解点为185-186℃;比旋光度[α] solution 23
        Refractive index6.8 ° (C=4, H2O)
        SolubilitySoluble in water (35 mg/ml at 20 °C), DMSO (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C). Insoluble in methanol, and ether.