1,2-Dimethoxyethane 乙二醇二甲醚

规格: 99%, SpcDry, Water≤50 ppm (by K.F.), SpcSeal
CAS: 110-71-4
产品编号: H35570
MDL: MFCD00008502
品牌: INFI
Chemical Name1,2-Dimethoxyethane
Synonym 2,5-Dioxahexane {LY} 2,5-Dioxahexane 2,5-dioxahexane Ansol E-121 CH3OCH2CH2OCH3 DME DME (glycol ether) DMEEthylene glycol dimethyl ether Dimethyl Dimethyl Cellosolve, Methyl Glycol Dimethyl Cellosolve, methyl Glycol Dimethyl cellosolve, Methyl glycol Dimethylglykol ETHYLENE GLYCOL DIMETHYL ETHER Egdme Ethane, 1,2-dimethoxy- Ethane-1,2-diol dimethyl ether Ethylene glycol dimethylether Glyme alpha,beta-Dimethoxyethane ethylene glycol dimethyl ether {} {LY} 2,5-Dioxahexane {} {} {LY} 2,5-Dioxahexane {} {} {} {LY} 2,5-Dioxahexane {} {} {} {} {LY} 2,5-Dioxahexane {} {} {} {} {} {LY} 2,5-Dioxahexane {} {} {} {} {} {} {LY} 2,5-Dioxahexane {} {} {} {} {} {} {} {LY} 2,5-Dioxahexane {} {} {} {} {} {} {} {} {LY} 2,5-Dioxahexane {} {} {
CAS Number110-71-4
PubChem Substance ID87567280
EC Number203-794-9
Beilstein Registry Number1209237
MDL NumberMFCD00008502
Reaxys-RN1209237
Merck Number3224
Chemical Name Translation乙二醇二甲醚
Wiswesser Line Notation1O2O1
LabNetwork Molecule IDLN00164056
InChIInChI=1S/C4H10O2/c1-5-3-4-6-2/h3-4H2,1-2H3
Canonical SMILESCOCCOC
GHS Symbol
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0539769

TYPE OF TEST            : LD50 - Let

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0539769

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0571323

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0571323

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TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 660 mg/kg
SEX/DURATION            : female 8-18 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   REPTED Reproductive Toxicology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1987-  Volume(issue)/page/year:
   5,157,1991

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1400 mg/kg
SEX/DURATION            : female 7-10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - Central Nervous System
REFERENCE :
   NISFAY Nippon Sanka Fujinka Gakkai Zasshi.  Journal of the Japan Society of
   Obstetrics and Gynecology.  (Nippon Sanka Fujinka Gakkai Zasshi, Hoken
   Kaikan Bekkan, 1-1 Sadohara-cho, Ichigaya, Shijuku-ku, Tokyo 162, Japan)
   V.1-    1949-  Volume(issue)/page/year: 32,113,1980

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 660 mg/kg
SEX/DURATION            : female 8-18 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - stillbirth
   Reproductive - Effects on Newborn - live birth index (measured after birth)
   Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4
   per # born alive)
REFERENCE :
   REPTED Reproductive Toxicology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1987-  Volume(issue)/page/year:
   5,157,1991

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Ro

WGK Germany1
Hazard Codes 3 F,T F;T
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
  • H332 Harmful if inhaled 吸入有害
    Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
    RTECSKI1451000
    Precautionary statements
    • P201 Obtain special instructions before use. 使用前获取专门指示。
    • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
    • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
    • P233 Keep container tightly closed. ?保持容器密闭。
    • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
    • P241+P242+P243
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P301+P312+P330
    • P303+P361+P353
    • P308+P313
    • P314 Get medical advice/attention if you feel unwell. 获取医疗咨询/就医，如果你觉得不舒服
    • P370+P378
    • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
    • P403+P235
    • P405 Store locked up. 上锁保管。
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Danger
      Safety Statements
      • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
      • S53 Avoid exposure - obtain special instructions before use 避免接触，使用前获得特别指示说明；
        Risk Statements
        • R11 Highly flammable 非常易燃
        • R19 May form explosive peroxides 可能生成易爆的过氧化物质
        • R20 Harmful by inhalation 吸入有害
        • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
        • R38 Irritating to skin 刺激皮肤
        • R60 May impair fertility 可能降低生殖能力
        • R61 May cause harm to the unborn child 可能对未出生的婴儿导致伤害
          UN Number 2252 UN2252
          Packing GroupII
          Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
          Hazard Class3
          Warnings 危化品目录(2015)
          Restrict 危险品
        • 用作溶剂和有机合成中间体。
        • {uni_hamburg} Short: II/25C
        • {ALD} Merck:14,3224
        • {ALFA} Solvent for lithiations and metal hydride reductions.
        • {ALD} Merck:14,3224
        • Beilstein:1,467
        • {ALFA} Recommended solvent for the Schmidt reaction of ketones with hydrazoic acid, avoiding potential hazards reported with the more usual chlorinated solvents, particularly chloroform. The hydrazoic acid is generated in situ from NaN3 and methanesulfonic acid: Tetrahedron, 52, 1609 (1996).
          • 110-71-4 H35570 1,2-Dimethoxyethane 乙二醇二甲醚

          化学属性

          Mol. FormulaC4H10O2
          Mol. Weight90.12
          Refractive index1.3790 to 1.3810
          Boiling Point85
          Density0.867
          Melting Point-58
          Flash Point0°C
          TSCAYes
          Autoignition Point396 °F
          Vapor Density3.1 (20 °C, vs air)
          Vapor Pressure48 mmHg ( 20 °C)
          Solubility溶于水、烃类。
          Stability对湿度敏感
          Danger-Level甲类

          *以上化合物性质及应用等信息仅供参考