n-Hexane 正己烷

规格: 97%
CAS: 110-54-3
产品编号: H36348
MDL: MFCD00009520
品牌: INFI
Chemical NameHexane
MDL NumberMFCD00009520
CAS Number110-54-3
EC Number203-777-6
Beilstein Registry Number1730733
Reaxys-RN1730733
Merck Number4694
PubChem Substance ID8058
Synonym Esani Gettysolve-B Heksan Hexane Hexanen Hexyl hydride NCI-C60571 n-Hexane 己烷 己烷,二丙基 己烷;二丙基 正己烷 正己烷, 99%
Chemical Name Translation正己烷
InChIKeyVLKZOEOYAKHREP-UHFFFAOYSA-N
Wiswesser Line Notation6H
LabNetwork Molecule IDLN00163099
InChIInChI=1S/C6H14/c1-3-5-6-4-2/h3-6H2,1-2H3
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 28710 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   19,699,1971

TYPE OF TEST            : LC50 - L

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 831 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
REFERENCE :
   APTOA6 Acta Pharmacologica et Toxicologica.  (Copenhagen, Denmark)  V.1-59,
   1945-86.  For publisher information, see PHTOEH  Volume(issue)/page/year:
   37,56,1975

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Human
DOSE/DURATION           : 190 ppm/8W
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - structural change in nerve or sheath
REFERENCE :
   AJIMD8 American Journal of Industrial Medicine.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.1-    1980-  Volume(issue)/page/year:
   10,111,1986

TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 120 gm/m3
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Lungs, Thorax, or Respiration - respiratory depression
   Cardiac - other changes
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 143,

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 132 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 341,83,1994

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Fibroblast
DOSE/DURATION           : 500 mg/L
REFERENCE :
   FCTOD7 Food and Chemical Toxicology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.20-    1982- Volume(issue)/page/year:
   22,623,1984

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 238 gm/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   DCTODJ Drug and Chemical Toxicology.  (Marcel Dekker, 270 Madison Ave., New
   York, NY 10016) V.1-    1977/78-  Volume(issue)/page/year: 3,393,1980

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 10000 ppm/7H
SEX/DURATION            : female 15 day(s) pre-mating
                          female 1-18 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - behavioral
REFERENCE :
   TOXID9 Toxicologist.  (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway,
   Akron, OH 44311) V.1-    1981-  Volume(issue)/page/year: 1,152,1981

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1000 ppm/6H
SEX/DURATION            : female 8-16 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 19,22A,1979

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 5000 ppm/20H
SEX/DURATION            : female 6-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicit

Signal word Danger
WGK Germany2
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S29 Do not empty into drains 不要排入下水道;
  • S30 Never add water to this product 切勿将水加入该产品中;
  • S33 Take precautionary measures against static discharges 对静电采取预防措施;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S43 In case of fire use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add -?Never use water) 着火时使用(指明具体的消防器材种类,如果用水增加危险,注明“禁止用水”
  • S57 Use appropriate containment to avoid environmental contamination 使用适当容器避免环境污染;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S62 If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label where possible 吞食后不要催吐:立即求医并出示该容器或标签;
  • S8 Keep container dry 保持容器干燥;
  • S9 Keep container in a well-ventilated place 保持容器在通风良好的场所;
    Risk Statements
    • R11 Highly flammable 非常易燃
    • R38 Irritating to skin 刺激皮肤
    • R48/20
    • R51/53
    • R62 Possible risk of impaired fertility 有削弱生殖能力的危险
    • R65 Harmful: may cause lung damage if swallowed 若吞咽可能伤害肺部器官
    • R67 Vapours may cause drowsiness and dizziness 蒸汽可能导致嗜睡和昏厥
      Precautionary statements
      • P201 Obtain special instructions before use. 使用前获取专门指示。
      • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
      • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
      • P273 Avoid release to the environment. 避免释放到环境中。
      • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
      • P301+P310
      • P303+P361+P353
      • P304+P340
      • P304+P340+P312
      • P305+P351+P338
      • P308+P313
      • P331 Do NOT induce vomiting.. 不要催吐。
      • P332+P313
      • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
      • P370+P378
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
        RTECSMN9275000
        UN Number 1208
        Hazard statements
        • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
        • H315 Causes skin irritation 会刺激皮肤
        • H304 May be fatal if swallowed and enters airways 吞食和进入呼吸道可能致命
        • H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
        • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
        • H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
        • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
          Hazard Codes 3
          Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
          Packing GroupII
          Storage condition 密封保存。
          Hazard Class3
          Warnings 危化品目录(2015)
          Restrict -
        • 溶剂。甲醇中水分测定。紫外光谱分析。农药残留分析。高效液相色谱。气相色谱分析标准。生化研究,蛋白质顺序分析。测定矿物折光率。有机合成。温度计中代替汞。
        • {ALD} Merck:14,4694
        • Beilstein: 1,IV,338
        • {ALD} Merck:14,4694
        • 化学属性

          Refractive indexn20/D 1.375(lit.)
          Flash Point-22°C(lit.)
          TSCAYes
          Melting Point-95
          Boiling Point69
          Autoignition Point453 °F
          Vapor Density~3 (vs air)
          Vapor Pressure256 mmHg ( 37.7 °C)
          Solubility不溶于水,溶于乙醇、乙醚等多数有机溶剂。
          Stability对湿度敏感
          Density0.639
          Mol. FormulaC6H14
          Mol. Weight86.00
          Danger-Level甲类
          pH-:-
          Redox-

          *以上化合物性质及应用等信息仅供参考