Ethylene Glycol 乙二醇

规格: 99%
CAS: 107-21-1
产品编号: H38789
MDL: MFCD00002885
品牌: INFI
Chemical NameEthylene glycol
MDL NumberMFCD00002885
CAS Number107-21-1
EC Number203-473-3
Beilstein Registry Number505945
Reaxys-RN505945
PubChem Substance ID174
Merck Number3798
Synonym Ethylene glycol,98% {LY} Ethylene glycol,98% {} {LY} Ethylene glycol,98% {} {} {LY} Ethylene glycol,98% {} {} {} {LY} Ethylene glycol,98% {} {} {} {} {LY} Ethylene glycol,98% {} {} {} {} {} {LY} Ethylene glycol,98% {} {} {} {} {} {} {LY} Ethylene glycol,98% {} {} {} {} {} {} {} {LY} Ethylene glycol,98% {} {} {} {} {} {} {} {} {LY} Ethylene glycol,98% {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Ethylene glycol,98% {} {} {} {} {} {} {} {} {} {} {LY} Ethylene glycol,98% {} {} {} {} {} {} {} {} {} {} {} {LY} Ethylene glycol,98% {} {} {} {} {} {} {} {} {} {} {} {} {LY} Ethylene glycol,98% {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Ethylene glycol,98% {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Ethylene glycol,98% {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Ethylene glycol,98% {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {}
Chemical Name Translation乙二醇
InChIKeyLYCAIKOWRPUZTN-UHFFFAOYSA-N
Wiswesser Line NotationQ2Q
LabNetwork Molecule IDLN00163543
InChIInChI=1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
Canonical SMILESOCCO
GHS Symbol
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 1637 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85DCAI "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M.,
   Springfield, IL, C.C. Thomas, 1970  Volume(issue)/page/year: 2,73,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 1195 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - sensory change involving peripheral nerve
   Kidney, Ureter, Bladder - renal function tests depressed
REFERENCE :
   AEMED3 Annals of Emergency Medicine.  (American College of Emergency
   Physicians, 1125 Executive Circle, Irving, TX 75038)
   Volume(issue)/page/year: 20,208,1991

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 15 gm/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - sensory change involving peripheral nerve
   Gastrointestinal - ulceration or bleeding from small intestine
   Kidney, Ureter, Bladder - renal functio

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 65,89,1939

TYPE OF TEST

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 320 mmol/L
REFERENCE :
   PNASA6 Proceedings of the National Academy of Sciences of the United States
   of America.  (National Academy of Sciences, Printing & Pub. Office, 2101
   Constitution Ave., Washington, DC 20418) V.1-    1915-
   Volume(issue)/page/year: 79,1171,1982

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 1200 mg/kg
REFERENCE :
   TGANAK Tsitologiya i Genetika.  Cytology and Genetics.  For English
   translation, see CYGEDX. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-    1967-  Volume(issue)/page/year: 19,436,1985

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 100 mmol/L
REFERENCE :
   PAACA3 Proceedings of the American Association for Cancer Research. (Waverly
   Press, 428 E. Preston St., Baltimore, MD 21202)  V.1-    1954-
   Volume(issue)/page/year: 21,74,1980

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 25 gm/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - uterus, cervix, vagina
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB85-104594

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 7500 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   81,113,1985

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 84 gm/kg
SEX/DURATION            : female 1-21 day(s) after conception
                          lactating female 21 day(s) post-birth
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - live birth index (measured after birth)
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
   Reproductive - Effects on Newborn - delayed effects
REFERENCE :
   TOXID9 Toxicologist.  (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway,

Signal word Warning
WGK Germany1
Safety Statements
  • S2 Keep out of the reach of children 避免儿童触及;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
    Risk Statements
    • R22 Harmful if swallowed 吞咽有害
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      Precautionary statements
      • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P301+P310
      • P305+P351+P338+P337+P313
      • P308+P311
      • P308+P313
      • P332+P313
      • P405 Store locked up. 上锁保管。
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
        RTECSKW2975000
        Hazard statements
        • H302 Harmful if swallowed 吞食有害
        • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
        • H303 May be harmfully swallowed 吞食可能有害
          Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
          Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
          Hazard Codes Xn Xn,Xi
        • 气相色谱固定液(最高使用温度50℃,溶剂为氯仿),分离分析低沸点含氧化合物、胺类化合物、氮或氧杂环化合物。测定水泥中的氧化钙, 溶剂, 抗冻剂, 制造聚酯树脂、增塑剂、化妆品、炸药、耐寒润滑油、表面活性剂、清漆、染料、油墨等, 有机合成。
        • {ALF} In combination with TMS chloride, ɑß-enones are converted to ß-chloro acetals in one step: Tetrahedron Lett., 25, 3805 (1984).
        • {ALF} For examples of use in acetal (1,3-dioxolane) formation, catalyzed by tosic acid with azeotropic water removal, see: Org. Synth. Coll., 6, 567 (1988); 7, 241, 271 (1990). A mild dehydrating agent, e.g. triethyl orthoformate may be used as an alternative: J. Org. Chem., 48, 2122 (1983). PPTS (Pyridinium p-toluenesulfonate, A15708) has been recommended as a catalyst for the formation and cleavage of ethylene acetals, being less likely to cause acid-catalyzed rearrangements than tosic acid itself: Synthesis, 724 (1979). For acetalization of ɑß-enals, tartaric acid in the presence of anhydrous MgSO4 gives good results: J. Org. Chem., 60, 2931 (1995). Review of the preparation of acetals: Synthesis, 501 (1981). See also 2,2-Dimethyl-1,3-dioxolane, L00482.
        • {ALD} Merck:14,3798
        • {ALD} Merck:14,3798
        • Beilstein:1,465
        • 107-21-1 H38789 Ethylene Glycol
乙二醇

          化学属性

          Mol. FormulaC2H6O2
          Mol. Weight62.07
          Density1.093
          Refractive index1.4300 to 1.4330
          Flash Point231.8 °F
          TSCAYes
          Boiling Point196 - 198 °C(lit.)
          Melting Point-13 °C
          Autoignition Point752 °F
          Vapor Density2.1 (vs air)
          Vapor Pressure0.08 mmHg ( 20 °C)
          Solubility与水混溶,可混溶于乙醇、醚等。
          Stability对湿度敏感
          pH:A

          *以上化合物性质及应用等信息仅供参考