研峰科技 Infinity Scientific

Phenothiazine 吩噻嗪

规格: 99%

CAS: 92-84-2

产品编号: H39458

MDL: MFCD00005015

品牌: INFI

Chemical Name	Phenothiazine
CAS Number	92-84-2
Synonym	Phenothiazine {LY} Phenothiazine {} {LY} Phenothiazine {} {} {LY} Phenothiazine {} {} {} {LY} Phenothiazine {} {} {} {} {LY} Phenothiazine {} {} {} {} {} {LY} Phenothiazine {} {} {} {} {} {} {LY} Phenothiazine {} {} {} {} {} {} {} {LY} Phenothiazine {} {} {} {} {} {} {} {} {LY} Phenothiazine {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {LY} Phenothiazine {} {} {} {} {} {} {} {} {} {} {LY} Phenothiazine {} {} {} {} {} {} {} {} {} {} {} {LY} Phenothiazine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenothiazine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenothiazine {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenothiazine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenothiazine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Phenothiazine {} {} {} {} {} {} {} {} {} {} {}
EC Number	202-196-5
Beilstein Registry Number	143237
MDL Number	MFCD00005015
Merck Number	7252
PubChem Substance ID	87574363
Reaxys-RN	143237
Chemical Name Translation	吩噻嗪
Wiswesser Line Notation	T C666 BM ISJ
LabNetwork Molecule ID	LN00195462
Canonical SMILES	C12=CC=CC=C1NC3=C(C=CC=C3)S2

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 4 gm/kg
TOXIC EFFECTS :

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Bird - wild bird species
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JACSAT Journal of the American Chemical Society.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
   20037)  V.1-    1879-  Volume(issue)/page/year: 66,888,1944

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - cattle
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,1104,1986

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - child
DOSE/DURATION           : 425 mg/kg/5D
TOXIC EFFECTS :
   Behavioral - headache
   Liver - jaundice, other or unclassified
   Blood - normocytic anemia
REFERENCE :
   LANCAO Lancet.  (7 Adam St., London WC2N 6AD, UK)  V.1-    1823-
   Volume(issue)/page/year: 242,86,1942

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Behavioral - antipsychotic
REFERENCE :
   DNEUD5 Developments in Neuroscience (Amsterdam).  (Elsevier Science Pub.
   Co., Inc., 52 Vanderbilt Ave., New York, NY 10017)  V.1-    1977-
   Volu

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1250 mg/kg
SEX/DURATION            : female 1-22 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   AJANA2 American Journal of Anatomy.  (Alan R. Liss, Inc., 41 E. 11th St.,
   New York, NY 10003) V.1-192, 1901-91.  Volume(issue)/page/year: 110,29,1962

Signal word
WGK Germany	3
Safety Statements
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套； S24 Avoid contact with skin 避免皮肤接触； S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书； S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见； S37 Wear suitable gloves 戴适当手套； S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护； S36 Wear suitable protective clothing 穿戴适当的防护服； S29 Do not empty into drains 不要排入下水道；
Risk Statements
R52/53 R48/22 R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应 R22 Harmful if swallowed 吞咽有害
Precautionary statements
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。 P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。 P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。 P305+P351+P338 P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。 P403+P233 P501 Dispose of contents/container to..… 处理内容物/容器..... P273 Avoid release to the environment. 避免释放到环境中。 P307+P311 P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。 P302+P350 P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。 P302+P352+P333+P313+P362+P364 P337+P313
RTECS	SN5075000
Storage condition	2-8°C {LY} 2-8°C Light Sensitive {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Hazard statements
H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。 H317 May cause an allergic skin reaction 可能导致皮肤过敏 H302 Harmful if swallowed 吞食有害 H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官 H303 May be harmfully swallowed 吞食可能有害
Personal Protective Equipment	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes	Xn Xi;N Xi Xi,N

A rigid, tricyclic thiazine useful as an electron donor.

{ALD} Merck: 14,7252

Beilstein:27,63

{ALF} Lithiation in THF gives orange crystals of (phenothiazin-10-yl)lithium.3THF. Carboxylation and the orientation of a second lithiation have been studied: Angew. Chem. Int. Ed., 34, 921 (1995).

{uni_hamburg} Short: II/27B

{TRC} ########

{uni_hamburg} Short: III/20a

{ALD} Merck: 14,7252

化学属性

Mol. Formula	C12H9NS
Mol. Weight	199.278
Density	1.362
TSCA	Yes
Boiling Point	371.003 °C at 760 mmHg
Melting Point	184 °C
Refractive index	1.6353
Solubility	Soluble in water (0.13 mg/ml at 23 °C), ethanol, acetone (very), and ether (freely). Insoluble in chloroform.
Stability	对光线、空气敏感
Flash Point	202°C

*以上化合物性质及应用等信息仅供参考