Bromotripyrrolidinophosphonium hexafluorophosphate 三吡咯烷基溴化鏻六氟磷酸盐

规格: 97%
CAS: 132705-51-2
产品编号: H39515
MDL: MFCD00077412
品牌: INFI
Chemical NameBromotripyrrolidinophosphonium hexafluorophosphate
CAS Number132705-51-2
Alfabeta NameBROMOTRIPYRROLIDINYLPHOSPHONIUMHEXAFLUOROPHOSPHATE V1(())--
MDL NumberMFCD00077412
Synonym BROMO-TRIS-PYRROLIDINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE PyBroP\(rg BROMO-TRIS-PYRROLIDINO-PHOSPHONIUM HEXFLUOROPHOSPHATE PyBroP PYBROP(TM) Bromo-tris-pyrrolidino-phosphonium hexafluorophosphat Bromotri(1-pyrrolidinyl)phosphonium hexafluorophosphate, 97% Pybrop(Bromo-Tris-PyrrolidinophosphoniumHexafluorophosphate) 溴-三吡咯烷基磷代六氟磷酸酯 PYBROP(R) Bromotri(pyrrolidin-1-yl)phosphoniumhexafluorophosphate PYBROP 三吡咯烷基溴化六氟磷酸盐 BROMOTRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE PyBroP® Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate ,97% Pyrrolidine phosphorus complex 三吡咯烷基溴化鏻六氟磷酸盐
PubChem Substance ID160871368
Beilstein Registry Number6842340
EC Number000-000-0
Chemical Name Translation三吡咯烷基溴化鏻六氟磷酸盐
Reaxys-RN6842340
GHS Symbol
Warnings IRRITANT
WGK Germany3
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P302+P352+P332+P313+P362+P364
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P332+P313
  • P305+P351+P338+P337+P313
  • P302+P350
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P337+P313
    Hazard statements
    • H315 Causes skin irritation 会刺激皮肤
    • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
      Hazard Codes C Xi
      Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
      Signal word Danger Warning
      Safety Statements
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
      • S37 Wear suitable gloves 戴适当手套；
      • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
      • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
      • S27 Take off immediately all contaminated clothing 立即脱掉全部污染的衣服；
      • S36 Wear suitable protective clothing 穿戴适当的防护服；
        Risk Statements
        • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
        • R34 Causes burns 会导致灼伤
          Storage condition Moisture Sensitive -20°C <0°C 储存温度 -20°C
        • 多肽缩合剂，适宜于烃基双取代的氨基酸，用于Depsipeptide的合成。
        • {SA}
        • 1. Vassiliki Theodorou, et al Tetrahedron 67 , 5630-5634, (2011)
        • {SA}
        • 2. Fu-An Kang, et al Chem. Commun. 46 , 1347-1349, (2010)
        • {SA}
        • 3. Fu-An Kang, et al J. Am. Chem. Soc. 130 , 1130-11302, (2008)
        • {SA}
        • 4. Jordi Alsina, et al Lett. Pept. Sci. 6 , 243-245, (1999)
        • {SA}
        • 5. J. Coste et al. J. Org. Chem. 59 , 2437, (1994)
        • {SA}
        • 6. T. Kurome et al. Tetrahedron 52 , 4327, (1996)
        • {ALF} Efficient peptide coupling agent for N-methylated amino esters for which coupling with a number of conventional reagents has proved ineffective or slow, and giving superior results to 1H-Benzotriazol-1-yl&#x00AD;oxytri(1-pyrrolidinyl)&#x00AD;phosphonium hexafluorophosphate, B25251, in this type of reaction: J. Org. Chem., 59, 2437 (1994). See Appendix 6.
        • {ALF} Can also be used to activate formamides, e.g. reaction of DMF with primary amines to yield formamidines: Tetrahedron Lett., 40, 5487 (1999).
          • 132705-51-2 H39515 Bromotripyrrolidinophosphonium hexafluorophosphate 三吡咯烷基溴化鏻六氟磷酸盐

          化学属性

          Mol. FormulaC12H24BrF6N3P2
          Mol. Weight466
          TSCANo
          Density1.422
          Melting Point>100°C
          SolubilityDMF: 0.4 g/mL, clear
          Stability对湿度敏感

          *以上化合物性质及应用等信息仅供参考