Triphenylphosphine oxide 三苯基氧膦

规格: 99%
CAS: 791-28-6
产品编号: H42991
MDL: MFCD00002080
品牌: INFI
Chemical NameTriphenylphosphine Oxide
Synonym Triphenylphosphine oxide {LY} Triphenylphosphine oxide {} {LY} Triphenylphosphine oxide {} {} {LY} Triphenylphosphine oxide {} {} {} {LY} Triphenylphosphine oxide {} {} {} {} {LY} Triphenylphosphine oxide {} {} {} {} {} {LY} Triphenylphosphine oxide {} {} {} {} {} {} {LY} Triphenylphosphine oxide {} {} {} {} {} {} {} {LY} Triphenylphosphine oxide {} {} {} {} {} {} {} {} {LY} Triphenylphosphine oxide {} {} {} {} {} {} {} {} {} {LY} Triphenylphosphine oxide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Triphenylphosphine oxide {} {} {} {} {} {} {} {} {} {} {} {LY} Triphenylphosphine oxide {} {} {} {} {} {} {} {} {} {} {} {} {LY} Triphenylphosphine oxide {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Triphenylphosphine oxide {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Triphenylphosphine oxide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Triphenylphosph
PubChem Substance ID13097
EC Number212-338-8
Beilstein Registry Number745854
Reaxys-RN745854
Chemical Name Translation三苯基氧化磷
LabNetwork Molecule IDLN00188054
InChIInChI=1S/C18H15OP/c19-20(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H
MDL NumberMFCD00002080
CAS Number791-28-6
Canonical SMILESO=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3
GHS Symbol
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - aggression
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0570648

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1380 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   KHFZAN Khimiko-Farmatsevticheskii Zhurnal.  Chemical Pharmaceutical Journal.
    For English translation, see PCJOAU.  (V/O Mezhdunarodnaya Kniga, 113095
   Moscow, USSR)  V.1-    1967-  Volume(issue)/page/year: 24(4),22,1990

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - chicken
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0570648

WGK Germany2
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
    Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
    RTECSSZ1676000
    Precautionary statements
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P305+P351+P338
    • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Warning
      Safety Statements
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
      • S36 Wear suitable protective clothing 穿戴适当的防护服；
      • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
      • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
        Risk Statements
        • R22 Harmful if swallowed 吞咽有害
        • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
        • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
        • R50/53
        • R52/53
          Hazard Codes Xn,N,Xi Xn
          UN Number UN 3077 9/PG 3 3077
          Packing GroupIII
          Hazard Class9
          Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
        • A phosphine ligand used for coupling reactions, epoxidations, and Michael reactions
        • {ALD} Beilstein:16,783
        • {uni_hamburg} Short: III/10b
        • {uni_hamburg} Short: III/35D2
        • {ALF} The reagent prepared from a 2:1 molar ratio of the phosphine oxide and triflic anhydride is a useful dehydrating agent, e.g. for preparation of nitriles from amides or oximes, or of amides from acids and amines: J. Org. Chem., 52, 4137 (1987). In combination with triethylamine, the reagent also dehydrates activated ketones to alkynes: Synthesis, 217 (1989).
        • {uni_hamburg} Short: III/20a
          • 791-28-6 H42991 Triphenylphosphine oxide 三苯基氧膦

          化学属性

          TSCAYes
          Boiling Point360 °C at 760 mmHg
          Solubility略溶于水
          Refractive indexn20/D 1.59(lit.)
          Mol. FormulaC18H15OP
          Mol. Weight278.28
          Density1.212
          Flash Point180°C
          Appearance white xtl.
          Melting Point150-157°C

          *以上化合物性质及应用等信息仅供参考