Polyethylene-polypropylene glycol 聚醚

规格: F127,average Mn ~10000-12000
CAS: 9003-11-6
产品编号: H50796
MDL: MFCD00082049
品牌: INFI
MDL NumberMFCD00082049
PubChem Substance ID24751
CAS Number9003-11-6
Synonym L Lμtrol® micro 68 Poloxamer 188, micronized PEG-PPG-PEG PEG-PPG-PEG Pluronic® F-108 PEG-PPG-PEG Pluronic® F-68 PEG-PPG-PEG Pluronic® L-31 Pluronic® L31 PEG-PPG-PEG Pluronic® L-35 PEG-PPG-PEG Pluronic® L-61 PEG-PPG-PEG Pluronic® P-123 PPG-PEG-PPG PPG-PEG-PPG Pluronic® 17R4 PPG-PEG-PPG Pluronic® 31R1 Pluronic F68 Pluronic L62 Pluronic® 10R5 Pluronic® F-108 Pluronic® F-68 solution Pluronic® F-68 溶液 Pluronic® F-68 Pluronic® P-123, Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) Poloxamer Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) 聚(丙二醇)-嵌段-聚(乙二醇)-嵌段-聚(丙二醇) 聚(乙二醇)-嵌-聚(丙二醇)-嵌-聚(乙二醇) 聚(乙二醇)-嵌-聚(丙二醇)-嵌-聚(乙二醇) 聚丙二醇-聚乙二醇
Chemical NameThylene Oxide-Propylene Oxide Copolymer
Chemical Name Translation乙二醇丙二醇嵌段共聚物
LabNetwork Molecule IDLN00195839
InChIInChI=1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1830 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 34(Suppl),533,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,797,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1140 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 34(Suppl),533,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >30300 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YAKUD5 Gekkan Yakuji.  Pharmaceuticals Monthly.  (Yakugyo Jihosha, Inaoka
   Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan)  V.1-   1959-
   Volume(issue)/page/year: 23,2291,1981

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous

GHS Symbol
WGK Germany1
RTECSMD0911050
Personal Protective Equipment Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US) Eyeshields, Gloves Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
    Precautionary statements
    • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
    • 非离子表面活性剂,软硬表面清洁剂、涂料和水处理中的消泡剂。金属加工润滑剂，线性和交联聚酯及聚氨酯的消泡助剂和增量剂。
      • 9003-11-6 H50796 Polyethylene-polypropylene glycol 聚醚

      化学属性

      Density1.075
      Boiling Point>200 °C(lit.)
      Refractive indexn20/D 1.461
      Mol. FormulaN/A
      Mol. Weight102.13
      Vapor Density>;1 (vs air)
      Vapor Pressure<;0.3 mmHg ( 20 °C)
      Melting Point56 - 62 °C
      Flash Point>230 °F

      *以上化合物性质及应用等信息仅供参考