1-Octanol 1-辛醇

规格: 99%, SpcDry, with molecular sieves, Water≤50 ppm (by K.F.), SpcSeal
CAS: 111-87-5
产品编号: H53750
MDL: MFCD00002988
品牌: INFI
Chemical Name1-Octanol
Synonym 1-Octanol {LY} 1-Octanol n-Octyl Alcohol {} {LY} 1-Octanol {} {} {LY} 1-Octanol {} {} {} {LY} 1-Octanol {} {} {} {} {LY} 1-Octanol {} {} {} {} {} {LY} 1-Octanol {} {} {} {} {} {} {LY} 1-Octanol {} {} {} {} {} {} {} {LY} 1-Octanol {} {} {} {} {} {} {} {} {LY} 1-Octanol {} {} {} {} {} {} {} {} {} {LY} 1-Octanol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Octanol {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Octanol {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Octanol {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Octanol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Octanol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Octanol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Octanol {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1-Octanol {} {} {} {} {} {} {} {}
CAS Number111-87-5
EC Number203-917-6
Beilstein Registry Number1697461
MDL NumberMFCD00002988
Reaxys-RN1697461
PubChem Substance ID957
Merck Number6751
Chemical Name Translation1-辛醇
Wiswesser Line NotationQ8
LabNetwork Molecule IDLN00162854
Canonical SMILESOCCCCCCCC
InChIInChI=1S/C8H18O/c1-2-3-4-5-6-7-8-9/h9H,2-8H2,1H3
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >3200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 11,95,1973

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 1240 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 50,296,1935

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 69 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 135,330,1962

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1790 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HYSAAV Hygiene and Sanitation (USSR).  English translation of GISAAA.
   (Springfield, VA)  1964-71.

TYPE OF TEST            : LCLo - Lowest published lethal concen

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 800 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 182,135,1987

WGK Germany1
Hazard Codes Xi
Hazard statements
  • H227 Combustible liquid 可燃液体
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
    Personal Protective Equipment Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
    RTECSRH6550000
    Precautionary statements
    • P201 Obtain special instructions before use. 使用前获取专门指示。
    • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
    • P203
    • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
    • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P264+P265
    • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
    • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
    • P273 Avoid release to the environment. 避免释放到环境中。
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
    • P301+P310
    • P301+P312
    • P301+P316
    • P301+P317
    • P302+P352
    • P304+P340
    • P305+P351+P338
    • P307+P311
    • P308+P313
    • P308+P316
    • P309+P311
    • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
    • P317
    • P318
    • P319
    • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
    • P322 Specific measures (see …on this label). 具体治疗（见本标签上的）。
    • P330 Rinse mouth. 漱口
    • P331 Do NOT induce vomiting.. 不要催吐。
    • P332+P313
    • P332+P317
    • P337+P313
    • P337+P317
    • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
    • P362+P364
    • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
    • P370+P378
    • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
    • P403 Store in a well-ventilated place. 储存在通风良好的地方。
    • P403+P233
    • P403+P235
    • P405 Store locked up. 上锁保管。
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
      Signal word Warning
      Safety Statements
      • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
      • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
        Risk Statements
        • R36 Irritating to eyes 刺激眼睛
        • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
        • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
          Packing GroupIII
          Hazard Class9
          Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
          UN Number 3082
        • 溶剂, 增香剂, 消泡剂, 有机合成，代替戊醇还原酮类, 制造香料, 气相色谱分析标准。
        • {MCE} [2]. Akhtar MK, et al. Microbial production of 1-octanol: A naturally excreted biofuel with diesel-like properties. Metab Eng Commun. 2014 Nov 13;2:1-5.
        • {ALD} Merck:14,6751
        • {uni_hamburg} Short: II/27B
        • {uni_hamburg} Short: II/5
        • {uni_hamburg} Short: III/38A
        • {MCE} [1]. Joksovic PM, et al. Mechanisms of inhibition of T-type calcium current in the reticular thalamic neurons by 1-octanol: implication of the protein kinase C pathway. Mol Pharmacol. 2010 Jan;77(1):87-94.
        • {MCE} [1]. Joksovic PM, et al. Mechanisms of inhibition of T-type calcium current in the reticular thalamic neurons by 1-octanol: implication of the protein kinase C pathway. Mol Pharmacol. 2010 Jan;77(1):87-94.
        • {MCE} [2]. Akhtar MK, et al. Microbial production of 1-octanol: A naturally excreted biofuel with diesel-like properties. Metab Eng Commun. 2014 Nov 13;2:1-5.
          • 111-87-5 H53750 1-Octanol 1-辛醇

          化学属性

          Mol. FormulaC8H18O
          Mol. Weight130.23
          Density0.827
          Refractive index1.4280 to 1.4310
          Boiling Point196 °C at 760 mmHg
          Melting Point-15 °C
          Flash Point81.11°C
          TSCAYes
          Autoignition Point523 °F
          Vapor Density4.5 (vs air)
          Vapor Pressure0.14 mmHg ( 25 °C)
          Solubility不溶于水，溶于乙醇、乙醚、氯仿。
          Stability对湿度敏感
          Appearance liquid

          *以上化合物性质及应用等信息仅供参考