4-Bromofluorobenzene 对氟溴苯

规格: 98%
CAS: 460-00-4
产品编号: H55232
MDL: MFCD00000342
品牌: INFI
Chemical Name4-Bromofluorobenzene
CAS Number460-00-4
MDL NumberMFCD00000342
PubChem Substance ID9993
EC Number207-300-2
Beilstein Registry Number5,209
Synonym 4-Fluorobromobenzene P-BROMOFLUOROBENZENE 4-Fluorophenyl bromide 1-bromo-4-fluoro-benzen 1-Bromo-4-fluorobenzene 对氟溴苯;4-溴氟苯;1-溴-4-氟苯 p-fluorophenylbromide p-Fluorbrombenzol 1-Fluoro-4-bromobenzene 1-氟-4-溴苯 nsc10268 4-bromofluorobenzene 4-FLUOROBROMOBENZENE 4-Bromo-1-fluorobenzene Benzene, 1-bromo-4-fluoro- 1-溴-4-氟苯 1-Bromo-4-fluorobenzene; p-Bromofluorobenzene Benzene,1-bromo-4-fluoro- 4-fluorophenylbromide 4-Bromofluorobenzene
Chemical Name Translation对氟溴苯
LabNetwork Molecule IDLN00176996
GHS Symbol
WGK Germany3
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H332 Harmful if inhaled 吸入有害
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
    Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
    Hazard Codes Xn
    Precautionary statements
    • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
    • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
    • P305+P351+P338
    • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
    • P332+P313
    • P501 Dispose of contents/container to..… 处理内容物/容器.....
    • P337+P313
    • P305+P351+P338+P337+P313
    • P303+P361+P353
    • P201 Obtain special instructions before use. 使用前获取专门指示。
    • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
    • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
    • P403+P235
    • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
    • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
    • P241+P242+P243
    • P233 Keep container tightly closed. ?保持容器密闭。
      Signal word
      Safety Statements
      • S36 Wear suitable protective clothing 穿戴适当的防护服;
      • S7 Keep container tightly closed 保存在严格密闭容器中;
      • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
      • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
      • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
      • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
      • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
      • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
        Risk Statements
        • R10 Flammable 易燃
        • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
          Storage condition <;0 <0°C 储存温度2-8℃ 0-6°C
          UN Number 1993
          Packing GroupIII
          Hazard Class3
        • 有机合成中间体。
        • Short: III/20b
        • Short: III/31b
        • The Br undergoes selective displacement with Na alkoxides in NMP, in the presence of CuBr: Tetrahedron, 48, 3633 (1992).
        • Lithiation with LDA at -75o results mainly in deprotonation ortho to F; subsequent reaction with CO2 gives 5-bromo-2-fluorobenzoic acid: Tetrahedron Lett., 33, 7495 (1992). Improved yields are obtained by the use of Li 2,2,6,6-tetramethylpiperidide (LTMP) as base: Tetrahedron Lett., 37, 6551 (1996).
        • Beilstein: 5,IV,678
        • 460-00-4 H55232 4-Bromofluorobenzene


          Mol. FormulaC6H4BrF
          Mol. Weight175.00
          Refractive index1.5260 to 1.5290
          Boiling Point153°C(lit.)
          Melting Point-16
          Flash Point56°C(lit.)
          Appearance 1.5270,相对密度 1.593,不溶于水,溶于苯、甲苯、醚等有机溶剂。 1-溴-4-氟苯是无色液体,m.p.-16℃,b.p.150℃,n 20