Propiolic acid 丙炔酸

规格: 95%
CAS: 471-25-0
产品编号: H62369
MDL: MFCD00004360
品牌: INFI
Chemical NamePropiolic acid
Synonym 乙炔甲酸 Propiolic acidd Propargylic acid Acetylencarbonsäure (Z)-2-Propynoic Acid HCequivCCOOH Acetylenecarboxylic acid 2-PROPYNOIC ACID Acetylenecarboxylic acid~Propargylic acid~Propynoic acid Propiolic acid, 98+% propiolic Propynoic acid Carboxyacetylene
MDL NumberMFCD00004360
CAS Number471-25-0
EC Number207-437-8
Beilstein Registry Number2,477
Merck Number7821
PubChem Substance ID10110
Reaxys-RN878176
Chemical Name Translation丙炔酸
LabNetwork Molecule IDLN00221630
InChIInChI=1S/C3H2O2/c1-2-3(4)5/h1H,(H,4,5)
GHS Symbol
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton,
   G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82.
   Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985.
   Volume(issue)/page/year: 2C,4953,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton,
   G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82.
   Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985.
   Volume(issue)/page/year: 2C,4953,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton,
   G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82.
   Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985.
   Volume(issue)/page/year: 2C,4953,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   38MKAJ "Patty

Signal word
WGK Germany3
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
    Risk Statements
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      Precautionary statements
      • P305+P351+P338
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
      • P302+P350
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P305+P351+P338+P310
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P301+P330+P331+P310
      • P303+P361+P353
      • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
      • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
      • P304+P340+P310
      • P403+P235
      • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
      • P241+P242+P243
      • P303+P361+P353+P310+P363
      • P405 Store locked up. 上锁保管。
      • P233 Keep container tightly closed. ?保持容器密闭。
        RTECSUD9300000
        Packing GroupII
        UN Number 2920
        Hazard statements
        • H226 Flammable liquid and vapour 易燃液体和蒸气
        • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
        • H310 Fatal in contact with skin 皮肤接触致命
        • H301 Toxic if swallowed 吞食有毒
          Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
          Hazard Codes T
          Storage condition 储存温度2-8℃ 2-8°C
          Hazard Class8/3
          Warnings 危化品目录(2015)
        • 用于有机合成。
        • Short: II/19b
        • Short: II/14a
        • Merck: 14,7821 Beilstein:2,477
        • Merck: 14,7821
        • Alkylation of the dilithio-derivative leads to higher 2-alkynoic acids. Reaction with epoxides, partial reduction (Lindlar) of the triple bond and cyclization has been used in the synthesis of unsaturated lactones: Tetrahedron Lett., 2615 (1974); J. Org. Chem., 40, 1610 (1975).
        • Short: II/22a
        • Propiolic acid
丙炔酸

          化学属性

          Mol. FormulaC3H2O2
          Mol. Weight70.05
          Density1.138
          Refractive index1.4290 to 1.4350
          Flash Point58°C(lit.)
          TSCAYes
          Boiling Point58°C/12mmHg(lit.)
          Melting Point16-18
          SolubilityMISCIBLE