Purine 嘌呤碱

规格: 98%
CAS: 120-73-0
产品编号: H64480
MDL: MFCD00079221
品牌: INFI
Chemical NamePurine
CAS Number120-73-0
Alfabeta NamePURINE
MDL NumberMFCD00079221
Synonym 1H-Purine 1H-Purine (9CI) 3,5,7-Triazaindole 3H-imidazo[4,5-d]pyrimidine 6H-Imidazo[4,5-d]pyrimidine 7(9)H-purine 7H-IMIDAZO[4,5-D]PYRIMIDINE 7H-Imidazo(4,5-d)pyrimidin 7H-Imidazo(4,5-d)pyrimidine 7H-Imidazo[4,5-d]pyrimidine 7H-Purine 7H-咪唑[4,5-d]嘧啶 9H-Purine 9H-PURINE 9H-Purine 9H-Purine; 7H-Imidazo[4,5-d]pyrimidine Imidazo(4,5-d)pyrimidine Isopurine NSC 753 PURINE Purine N(7)H Purine N(9)H Purine free base Purine,>98% TIMTEC-BB SBB004288 X 128 beta-Purine imidazolopyrimidine β-Purine 咪唑并嘧啶 嘌呤 嘌呤(试剂)
EC Number204-421-2
Beilstein Registry Number3200
PubChem Substance ID24898673
Merck Number7942
Reaxys-RN606899
Chemical Name Translation嘌呤碱
Wiswesser Line NotationT56 BM DN FN HNJ
LabNetwork Molecule IDLN00174569
GHS Symbol
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 156 mg/kg/8W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   38,2229,1978

TYPE OF TEST            : LD10 - Lethal Dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Blood - changes in bone marrow (not otherwise specified)
REFERENCE :
   PMDCAY Progress in Medical Chemistry.  (Elsevier Science Pub. Co., Inc., 52
   Vanderbilt Ave., New York, NY 10017)  V.1-    1961- Volume(issue)/page/year:
   7,69,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ADTEAS Advances in Teratology.  (New York, NY)  V.1-5, 1966-72.
   Discontinued.  Volume(issue)/page/year: 3,181,1968

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Mammal - species unspecified Lymphocyte
DOSE/DURATION           : 50 mmol/L
REFERENCE :
   PNASA6 Proceedings of the National Academy of Sciences of the United States
   of America.  (National Academy of Sciences, Printing & Pub. Office, 2101
   Constitution Ave., Washington, DC 20418) V.1-    1915-
   Volume(issue)/page/year: 48,686,1962

TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 1 gm/L
REFERENCE :
   ZAPOAK Zeitschrift fuer Allgemeine Mikrobiologie.  (Akademie-Verlag GmbH,
   Postfach 1233, Berlin DDR-1086 Ger. Dem. Rep.)  V.1-    1960-
   Volume(issue)/page/year: 12,583,1972

Warnings IRRITANT
Signal word Warning
WGK Germany3
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘；
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
    Risk Statements
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      Precautionary statements
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
        RTECSUO7450000
        Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
        Storage condition 2-8°C
        UN Number
        Hazard Codes
        Packing Group
      • {uni_hamburg} Short: II/25D
      • Title: Structure Data of Free Polyatomic Molecules: Molecules Containing Five or More Carbon Atoms
      • Author: Graner, G.; Hirota, E.; Iijima, T.; Kuchitsu, K.; Ramsay, D.A.; Vogt, J.; Vogt, N.
      • Editor: Kuchitsu, K.
      • Source: Landolt-Börnstein, New Series
      • Volume: II/25D
      • Year: 2003
      • Keyword: Free Polyatomic Molecules; Carbon Atoms; Molecules
      • ISBN: 3-540-42860-7
      • ISBN: 978-3-540-42860-2
      • Internet Resource: DOI:10.1007/b75952
      • RefComment: VIII, 569 pages. Hardcover
      • RefComment: Written for scientists and researchers in the fields of chemistry and physics
      • Abstract: This fourth subvolume presents data on the geometric parameters (internuclear distances, bond angles, dihedral angles of internal rotation etc) of free polyatomic molecules including free radicals and molecular ions. The survey on structure data consists of four subvolumes, each containing the geometric parameters determined in the gas phase either by an analysis of the rotational constants (and sometimes the vibrational constants) obtained from microwave, infrared, Raman, electronic and photoelectron spectroscopy or by an analysis of electron diffraction intensities. Most of the structures listed in the tables are for molecules in the electronic ground state, but structures for electronically excited states have also been included as far as they are available. In this fourth subvolume, the structure of molecules containing five to sixty carbon atoms is listed.
      • {uni_hamburg} Short: III/35B
      • Title: Nuclear Magnetic Resonance (NMR) Data: Chemical Shifts and Coupling Constants for Fluorine-19 and Nitrogen-15
      • Author: Balasubramanian, M.; Gupta, R.R.; Jain, M.; Perumal, S.
      • Editor: Gupta, R.R.; Lechner, M.D.
      • Source: Landolt-Börnstein, New Series
      • Volume: III/35B
      • Year: 1998
      • ISBN: 3-540-63275-1
      • ISBN: 978-3-540-63275-7
      • Internet Resource: DOI:10.1007/b55685
      • RefComment: VII, 242 pages. With CD-ROM. Hardcover
      • Abstract: This volume provides a comprehensive and evaluated compilation of nuclear magnetic res
        • 120-73-0 H64480 Purine 嘌呤碱

        化学属性

        Mol. FormulaC5H4N4
        Mol. Weight120
        Density1.422
        Melting Point214-217 °C(lit.)
        Solubility400 G/L (20 ºC)
        TSCANo
        Boiling Point

        *以上化合物性质及应用等信息仅供参考