2-Methylindole-3-carboxaldehyde 2-甲基吲哚-3-甲醛

规格: 98%
CAS: 5416-80-8
产品编号: H65003
MDL: MFCD00012077
品牌: INFI
Chemical Name3-Formyl-2-Methylindole
CAS Number5416-80-8
Alfabeta NameMETHYLINDOLECARBALDEHYDE H213-----
MDL NumberMFCD00012077
Synonym 2-Methyl-1H-indole-3-carbaldehyde {LY} 2-Methyl-1H-indole-3-carbaldehyde {} {LY} 2-Methyl-1H-indole-3-carbaldehyde {} {} {LY} 2-Methyl-1H-indole-3-carbaldehyde {} {} {} {LY} 2-Methyl-1H-indole-3-carbaldehyde {} {} {} {} {LY} 2-Methyl-1H-indole-3-carbaldehyde {} {} {} {} {} {LY} 2-Methyl-1H-indole-3-carbaldehyde {} {} {} {} {} {} {LY} 2-Methyl-1H-indole-3-carbaldehyde {} {} {} {} {} {} {} {LY} 2-Methyl-1H-indole-3-carbaldehyde {} {} {} {} {} {} {} {} {LY} 2-Methyl-1H-indole-3-carbaldehyde {} {} {} {} {} {} {} {} {} {LY} 2-Methyl-1H-indole-3-carbaldehyde {} {} {} {} {} {} {} {} {} {} {LY} 2-Methyl-1H-indole-3-carbaldehyde {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Methyl-1H-indole-3-carbaldehyde {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Methyl-1H-indole-3-carbaldehyde {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Methyl-1H-indole-3-carbaldehyde {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-Methyl-1H-indole-3-carbaldehyde {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
PubChem Substance ID73166
EC Number226-512-6
Beilstein Registry Number21(5)8,306
Reaxys-RN121180
Chemical Name Translation2-甲基吲哚-3-甲醛
InChIKeyCYZIVXOEJNAIBS-UHFFFAOYSA-N
LabNetwork Molecule IDLN00003977
Canonical SMILESC1=CC=CC2=C1C(=C(C)[NH]2)C=O
InChIInChI=1S/C10H9NO/c1-7-9(6-12)8-4-2-3-5-10(8)11-7/h2-6,11H,1H3
GHS Symbol
Warnings IRRITANT
WGK Germany3
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
    Risk Statements
    • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
      Precautionary statements
      • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
      • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
      • P264+P265
      • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
      • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
      • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
      • P301+P312
      • P301+P317
      • P302+P352
      • P302+P352+P332+P313+P362+P364
      • P304+P340
      • P305+P351+P338
      • P305+P351+P338+P337+P313
      • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
      • P319
      • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
      • P330 Rinse mouth. 漱口
      • P332+P313
      • P332+P317
      • P337+P313
      • P337+P317
      • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
      • P362+P364
      • P403+P233
      • P405 Store locked up. 上锁保管。
      • P501 Dispose of contents/container to..… 处理内容物/容器.....
        Hazard statements
        • H302 Harmful if swallowed 吞食有害
        • H315 Causes skin irritation 会刺激皮肤
        • H319 Causes serious eye irritation 严重刺激眼睛
        • H335 May cause respiratory irritation 可能导致呼吸道刺激
          Hazard Codes Xn Xi
          Storage condition 2-8°C, stored under nitrogen {LY} 2-8°C, stored under nitrogen {} {LY} 2-8°C, stored under nitrogen {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, stored under nitro
        • Reactant for preparation of:
        • 1.Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators.
        • 2.Fluorescent sensors (BODIPY).
        • 3.Antimicrobial agents against methicillin-resistant Staphylococcus aureus.
        • 4.G protein-coupled receptor CRTh2 antagonists.
        • 5.Inhibitors of PI3 kinase-α.
        • 6.Antitubercular agents.
        • 7.Anti-inflammatory agents.
        • 8.Mycobacterium tuberculosis protein tyrosine phosphatase B.
        • 9.Glucocorticoid receptor ligands.
        • 10.Agents stimulating neurite outgrowth.
        • {SA}
        • 2. Lee, J.-S.; et al., Accelerating fluorescent sensor discovery: unbiased screening of a diversity-oriented BODIPY library Chem. Commun. 47 , 2339, (2011)
        • {SA}
        • 3. Al-Qawasmeh, R. A.; et al., Potent antimicrobial activity of 3-(4,5-diaryl-1H-imidazol-2-yl)-1H-indole derivatives against methicillin-resistant Staphylococcus aureus Bioorg. Med. Chem. Lett. 20 , 3518, (2010)
        • {SA}
        • 4. Tumey, L. N.; et al., 3-Indolyl sultams as selective CRTh2 antagonists Bioorg. Med. Chem. Lett. 20 , 3287, (2010) 摘要
        • {SA}
        • {SA} 5. Bursavich, M. G.; et al., Novel benzofuran-3-one indole inhibitors of PI3 kinase-a and the mammalian target of rapamycin: hit to lead studies Bioorg. Med. Chem. Lett. 20 , 2586, (2010)
        • {SA}
        • 6. Sonar, V. N.; Crooks, P. A., Synthesis and antitubercular activity of a series of hydrazone and nitrovinyl analogs derived from heterocyclic aldehydes J. Enzyme Inhib. Med. Chem. 24 , 117, (2009) 摘要
        • {SA}
        • {SA} 7. Singh, N.; et al., Thiazolyl/oxazolyl formazanyl indoles as potent anti-inflammatory agent Eur. J. Med. Chem. 43 , 2597, (2008) 摘要
        • {SA}
        • {SA} 9. Marshall, D. R.; et al., α-Methyltryptamine sulfonamide derivatives as novel glucocorticoid receptor ligands Bioorg. Med. Chem. Lett. 17 , 315, (2007) 摘要
        • {SA}
        • {SA} 10. Beck, B.; et al., Discovery of pyrroloimidazoles as agents stimulating neurite outgrowth QSAR Comb. Sci. 25 , 527, (2006)
        • {SA}
        • Dolusic, E.; et al., Tryptophan 2,3-Dioxygenase (TDO) Inhibitors. 3-(2-(Pyridyl)ethenyl)indoles as Potential Anticancer Immunomodulators J. Med. Chem. 54 , 5320, (2011) 摘要
        • {SA}
        • {SA} Noeren-Mueller, A.; et al., Discovery of a new class of inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B by biology-oriented synthesis Angew. Chem. Int. Ed. Engl. 47 , 5973, (2008) 摘要
        • {SA}
        • {SA} Beil. 21 ,316
        • {
        • 5416-80-8 H65003 2-Methylindole-3-carboxaldehyde	2-甲基吲哚-3-甲醛

          化学属性

          Mol. FormulaC10H9NO
          Mol. Weight159.19
          Melting Point200-201°C
          Density1.422
          Boiling Point344.3°C at 760 mmHg

          *以上化合物性质及应用等信息仅供参考